Reinventing Drug Delivery Through Cutting-Edge Nanotechnology

Year : 2025 | Volume : 12 | Issue : 03 | Page : 44 61
    By

    Maya Sharma,

  • Jayesh Kumar,

  • Ranu Sharma,

  • Ankit Paliwal,

  • Dileep Kumar,

  • Hemlata Salvi,

  1. Associate Professor, Pacific College of Pharmacy, Pacific Academy of Higher Education and Research University, Udaipur, Rajasthan, India
  2. Student, Pacific College of Pharmacy, Pacific Academy of Higher Education and Research University, Udaipur, Rajasthan, India
  3. Student, Pacific College of Pharmacy, Pacific Academy of Higher Education and Research University, Udaipur, Rajasthan, India
  4. Student, Pacific College of Pharmacy, Pacific Academy of Higher Education and Research University, Udaipur, Rajasthan, India
  5. Student, Pacific College of Pharmacy, Pacific Academy of Higher Education and Research University, Udaipur, Rajasthan, India
  6. Student, Pacific College of Pharmacy, Pacific Academy of Higher Education and Research University, Udaipur, Rajasthan, India

Abstract

Nanotechnology has emerged as a revolutionary platform in the field of drug delivery, offering novel strategies for the precise, efficient, and controlled delivery of therapeutic agents. The integration of nanocarriers, such as liposomes, polymeric nanoparticles, dendrimers, micelles, and inorganic nanoparticles, has significantly enhanced drug solubility, stability, bioavailability, and targeted delivery to specific tissues or cells. Targeted drug delivery systems based on nanotechnology minimize off-target effects, reduce systemic toxicity, and improve therapeutic outcomes, especially in the treatment of complex diseases like cancer, neurological disorders, cardiovascular diseases, and infectious diseases. This review highlights the fundamental principles of nanotechnology in drug delivery, discusses various types of nanocarriers and their functionalization strategies, and evaluates their role in achieving site-specific and stimuli-responsive drug release. Furthermore, we examine recent advancements, clinical applications, challenges, and future perspectives in the development of nanotechnology-based targeted drug delivery systems to achieve personalized and precision medicine.

Keywords: Nanotechnology, Targeted drug delivery, Nanocarriers, Controlled release, Cancer therapy, Precision medicine, Bioavailability, Stimuli-responsive systems.

[This article belongs to Trends in Drug Delivery ]

How to cite this article:
Maya Sharma, Jayesh Kumar, Ranu Sharma, Ankit Paliwal, Dileep Kumar, Hemlata Salvi. Reinventing Drug Delivery Through Cutting-Edge Nanotechnology. Trends in Drug Delivery. 2025; 12(03):44-61.
How to cite this URL:
Maya Sharma, Jayesh Kumar, Ranu Sharma, Ankit Paliwal, Dileep Kumar, Hemlata Salvi. Reinventing Drug Delivery Through Cutting-Edge Nanotechnology. Trends in Drug Delivery. 2025; 12(03):44-61. Available from: https://journals.stmjournals.com/tdd/article=2025/view=225241


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Regular Issue Subscription Review Article
Volume 12
Issue 03
Received 20/08/2025
Accepted 28/08/2025
Published 30/08/2025
Publication Time 10 Days
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