A Review on: Oral Thin Films: A New Approach to Effective and Easy Drug Delivery


Year : 2024 | Volume : 11 | Issue : 03 | Page : 22-41
    By

    P. N. Vaishnavi,

  • Vedant Patel,

  • Himanshu Solanki,

  1. Associate Professor, Department of Pharmaceutics, SSR College of Pharmacy, Union Territory of Dadra Nagar Haveli and Daman Diu, India
  2. Associate Professor, Department of Pharmaceutics, SSR College of Pharmacy, Union Territory of Dadra Nagar Haveli and Daman Diu, India
  3. Associate Professor, Department of Pharmaceutics, SSR College of Pharmacy, Union Territory of Dadra Nagar Haveli and Daman Diu, India

Abstract

Oral Thin Film (OTF) is an advance drug delivery system in which drug is incorporated into dissolvable strip and place in oral cavity for rapid absorption. OTF is useful for patient such as pediatric and geriatric who have difficulty swallowing pills. It provides rapid action, precise dosage and improved bioavailability. OTFs consist of fast-dissolving films, extended-release films, and mucoadhesive films for various therapeutic applications. The manufacturing processes of OTFs such as solvent casting, hot melt extrusion and semi-solid casting are specific to a particular formulation of the drug. OTFs can be used in many areas such as pain relief, antiemetics, allergy treatment, nutritional products and many others. However, despite these advantages, problems such as moisture sensitivity, low drug loading capacity, and stability issues remain that need to be addressed for wider application. Recent advances in nanotechnology and personalized medicine promise to broaden the scope and effectiveness of OTFs in the future.

Keywords: Mouth dissolving film, Solvent casting, Hot melt extrusion, Advantages, Challenges of OTF.

[This article belongs to Trends in Drug Delivery (tdd)]

How to cite this article:
P. N. Vaishnavi, Vedant Patel, Himanshu Solanki. A Review on: Oral Thin Films: A New Approach to Effective and Easy Drug Delivery. Trends in Drug Delivery. 2024; 11(03):22-41.
How to cite this URL:
P. N. Vaishnavi, Vedant Patel, Himanshu Solanki. A Review on: Oral Thin Films: A New Approach to Effective and Easy Drug Delivery. Trends in Drug Delivery. 2024; 11(03):22-41. Available from: https://journals.stmjournals.com/tdd/article=2024/view=180401


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Regular Issue Subscription Review Article
Volume 11
Issue 03
Received 03/10/2024
Accepted 15/10/2024
Published 28/10/2024
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