A Detailed Analysis: Liposomes Innovative Role as a Drug Delivery System

Year : 2024 | Volume :11 | Issue : 02 | Page : 25-33
By

Satbir Singh

Kehar Singh

Hemant Rana

Jaikaushik

Yakshita Saini

  1. Associate Professor Department of Pharmaceutics, Pt. LR College of Pharmacy, Faridabad Haryana India
  2. Associate Professor Department of Pharmaceutics, Pt. LR College of Pharmacy, Faridabad Haryana India
  3. Assistant Professor Department of Pharmaceutics, Pt. LR College of Pharmacy, Faridabad Haryana India
  4. Under Graduate Pt. LR College of Pharmacy, Faridabad Haryana India
  5. Under Graduate Pt. LR College of Pharmacy, Faridabad Haryana India

Abstract

The first nanomedicine to be approved for use in clinical settings was liposomes. These are the spherical vesicles with a bilayer of phospholipids enclosing a middle empty aqueous region. Because of their extraordinary potential to stop medication deterioration and lessen unwanted effects, liposomes are being utilized more and more for targeted drug distribution. For targeted drug delivery, the pharmaceuticals can be integrated into the liposomes’ aqueous space or phospholipid bilayer. In order to target a medication or substance to the active site at a predetermined rate and time range without impacting other body parts in the process, liposomes are available in a range of sizes to treat different sorts of diseases. Vesicular systems, as they are often called, are colloidal spheres composed of cholesterol, sphingolipids, glycolipids, long-chain unsaturated fats, layer proteins, and active atoms. They are also constituted of non-poisonous surfactants. Liposomes are one of the most often utilized methods in biological, pharmaceutical, medical, and nutritional research for the encapsulation and transport of a wide range of different compounds, including bioactive substances., benefits and drawbacks, as well as different approaches to preparation, assessment etc.. This paper examines the liposomal vesicles’ classification, manufacturing and encapsulating techniques, and uses in the food, cosmetics, and pharmaceutical industries. Furthermore, this section presents the primary analytical techniques utilized to investigate the properties of liposomes, including their size, stability, fluidity, lamellarity, surface charge, and encapsulation efficiency.

Keywords: Liposome, Evaluation, Drug delivery system, Vesicles, MLV, SUV.

[This article belongs to Trends in Drug Delivery(tdd)]

How to cite this article: Satbir Singh, Kehar Singh, Hemant Rana, Jaikaushik, Yakshita Saini. A Detailed Analysis: Liposomes Innovative Role as a Drug Delivery System. Trends in Drug Delivery. 2024; 11(02):25-33.
How to cite this URL: Satbir Singh, Kehar Singh, Hemant Rana, Jaikaushik, Yakshita Saini. A Detailed Analysis: Liposomes Innovative Role as a Drug Delivery System. Trends in Drug Delivery. 2024; 11(02):25-33. Available from: https://journals.stmjournals.com/tdd/article=2024/view=147278





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Regular Issue Subscription Review Article
Volume 11
Issue 02
Received May 3, 2024
Accepted May 13, 2024
Published May 22, 2024