Medicinal Properties of Oxytenanthera Abyssinica: A Narrative Review

Year : 2026 | Volume : 13 | 02 | Page :
    By

    Sharique Ahmad,

  • Subuhi Anwar,

  • Pushpendra D. Pratap,

  1. Professor, Department of Pathology, Era’s Lucknow Medical College and Hospital, Era University, Lucknow, Uttar Pradesh, India
  2. Research Assistant, Department of Pathology, Era’s Lucknow Medical College and Hospital, Era University, Lucknow, Uttar Pradesh, India
  3. Research Analyst, Department of Research Metabolic Unit, Research Metabolic Unit, Era’s Lucknow Medical College & Hospital, Era University, Lucknow, Uttar Pradesh, India

Abstract

Oxytenanthera abyssinica, a plant local to the African landmass, has gotten a parcel of intrigued in later a long time for its conceivable restorative benefits; it has been utilized in conventional medication for decades since of its assumed mending capabilities. In spite of its long history, careful logical examination into its restorative potential is being attempted. This review paper explore into the multidimensional part of O. Abyssinica is in progressed investigate, emphasizing its pharmacological action, restorative applications, and atomic components, as well as its conventional utilize, security profile, and future inquire about prospects in medication. Preclinical and clinical investigate are being conducted to explore O. Abyssinica has helpful potential in assortment of ailment states, counting cancer, diabetes, cardiovascular disease, neurological infections, and irresistible maladies. Methodology: a total writing look was carried out utilizing scholastic databases such as Pubmed, Science Coordinate, and Google Researcher. keywords such as “oxytenanthera abyssinica,” “restorative properties,” “conventional employments,” “phytochemistry,” and “safety” were utilized to discover pertinent studies. Oxytenanthera abyssinica shows a wide run of pharmacological action, counting antibacterial, anti-inflammatory, antioxidant, antidiarrheal, and antimicrobial, antidiabetic, anticancer, and neuroprotective activity. Progressed investigate strategies such as chromatography, spectroscopy, and atomic modelling have made a difference to illustrate the chemical components and bioactive agents of o. Abyssinica, giving imperative experiences into its restorative adequacy. Phytochemical considers have distinguished bioactive chemicals such as flavonoids, phenolic compounds, and alkaloids that contribute to restorative benefits. Oxytenanthera abyssinica has customarily been utilized in ethnomedicine to treat irresistible maladies, gastrointestinal issues, and skin concerns. Whereas preparatory information recommends viability, inquire about gaps exist, especially in clinical trials, mechanistic data, and toxicological studies about. There’s restricted data known on its security profile, potential medicate intelligent, and contraindications. In conclusion, oxytenanthera abyssinica appears impressive guarantee as a therapeutic plant, with assortment of pharmacological properties and conventional utilization demonstrating helpful potential. Be that as it may, consider impediments, such as a need of clinical considers and mechanistic investigations, make it troublesome to urge a comprehensive understanding of its adequacy and security. Future investigate ought to concentrate on well-designed clinical trials, deciding components of activity, assessing toxicological profiles, and examining potential pharmaceutical intelligent. Tending to these information will empower us to completely appreciate oxytenanthera abyssinica helpful potential and contribute to the improvement of novel medicines for a wide run of wellbeing issues. In expansion, endeavours ought to be made to coordinated ancient information with advanced logical approaches in arrange to optimize its application in healthcare operations.

Keywords: Medicinal properties, traditional uses, phytochemistry, pharmacological activities, drug discovery

How to cite this article:
Sharique Ahmad, Subuhi Anwar, Pushpendra D. Pratap. Medicinal Properties of Oxytenanthera Abyssinica: A Narrative Review. Research & Reviews: A Journal of Pharmacognosy. 2026; 13(02):-.
How to cite this URL:
Sharique Ahmad, Subuhi Anwar, Pushpendra D. Pratap. Medicinal Properties of Oxytenanthera Abyssinica: A Narrative Review. Research & Reviews: A Journal of Pharmacognosy. 2026; 13(02):-. Available from: https://journals.stmjournals.com/rrjopc/article=2026/view=246670


References

1. Belayneh, a., and n. F. Bussa. “ethnomedicinal plants used to treat human ailments in the prehistoric place of harla and dengego valleys, eastern ethiopia.” journal of ethnobiology and ethnomedicine 10 (february 5, 2014): 18. Doi:10.1186/1746-4269-10-18.
2. Getaneh, g., a. Zeynudin, h. Lemma, t. Mohammed, and t. Girma. “antibacterial activity of the ethanol extracts of eight traditional medicinal plants against human pathogens.” journal of medicinal plant research 5, no. 16 (2011): 3854-3860.
3. Addis, g., k. Urga, and d. Dikasso. “ethnobotanical study of medicinal plants in guji agro-pastoralists, blue hora district of borana zone, oromia regional state, ethiopia.” journal of medicinal plants studies 1, no. 4 (2013): 32-37.
4. Vandebroek, i., m. J. Balick, and a. Ososki. “the importance of botellas and other plant mixtures in dominican traditional medicine.” ethnobiology and conservation 8 (2019): 3.
5. Fabricant, d. S., and n. R. Farnsworth. “the value of plants used in traditional medicine for drug discovery.” environmental health perspectives 109, suppl. 1 (2001): 69–75.
6. World health organization. Who traditional medicine strategy: 2014–2023. 2013.
7. Etkin, n. L. “perspectives in ethnopharmacology: forging a closer link between bioscience and traditional empirical knowledge.” journal of ethnopharmacology 76, no. 3 (2001): 177–182.
8. Bannerman, r. H., j. Burton, and c. Wen-chieh. Traditional medicine and health care coverage: a reader for health administrators and practitioners. World health organization, 1983.
9. Pieroni, a., and i. Vandebroek. Traveling cultures and plants: the ethnobiology and ethnopharmacy of migrations. Berghahn books, 2007.
10. Schippmann, u., d. J. Leaman, and a. B. Cunningham. “impact of cultivation and gathering of medicinal plants on biodiversity: global trends and issues.” in biodiversity and the ecosystem approach in agriculture, forestry and fisheries, 1:140–167, 2002.
11. Farnsworth, norman r., olayiwola akerele, alicia s. Bingel, djaja d. Soejarto, and zhongzhen guo. “medicinal plants in therapy.” bulletin of the world health organization 63, no. 6 (1985): 965–981.
12. Negash, a., h. Jifar, z. Asfaw, and e. Kelbessa. “ethnobotanical study of wild edible plants used by koore of the kacha bira district, oromia region, ethiopia.” journal of ethnobiology and ethnomedicine 14, no. 1 (2018): 15.
13. Yineger, h., e. Kelbessa, t. Bekele, and e. Lulekal. “ethnoveterinary medicinal plants at bale mountains national park, ethiopia.” journal of ethnopharmacology 112, no. 1 (2007): 55–70.
14. Teketay, d. “the history, botany and ecology of bamboo in ethiopia: a review.” ethiopian journal of science 22, no. 1 (1999): 1–10.
15. Abebe, demissew, and sebsebe ayalew. “medicinal plants in ethiopia: origin, traditional medicinal use, practices, and benefits.” pharmacognosy reviews 8, no. 15 (2014): 1–11.
16. Bekele-tesemma, a. Useful trees and shrubs for ethiopia: identification, propagation and management for agricultural and pastoral communities. Relma in icraf project, nairobi, kenya, 2007.
17. Giday, mirutse, zemede asfaw, zerihun woldu, and tilahun teklehaymanot. “medicinal plant knowledge of the bench ethnic group of ethiopia: an ethnobotanical investigation.” journal of ethnobiology and ethnomedicine 5, no. 1 (2009): 34.
18. Sebsebe, m. R. D., et al. “a taxonomic revision of the genus oxytenanthera (poaceae: bambusoideae: bambuseae) in ethiopia.” kew bulletin 69, no. 1 (2014): 81–91. Doi:10.1007/s12225-014-9521-4.
19. Gebremedhin, e. Z., et al. “bamboo diversity and ethnobotany in ethiopia with special emphasis on the gurage people of snnprs.” journal of ethnobiology and ethnomedicine 9, no. 1 (2013): 39. Doi:10.1186/1746-4269-9-39.
20. Powell, m. H., et al. “the biodiversity and conservation status of montane forests in the ethiopian rift valley escarpment.” sinet: ethiopian journal of science 33, no. 1 (2010): 17–32.
21. Dalle, g., et al. “use and management of bamboo (oxytenanthera abyssinica) in the choke mountain range, ethiopia.” agroforestry systems 88, no. 5 (2014): 787–804. Doi:10.1007/s10457-014-9700-6.
22. O’brien, e. M. Economic botany: plants in our world. Mcgraw-hill education, 2011.
23. Gemedo-dalle, t., b. L. Maass, and j. Isselstein. “plant biodiversity and ethnobotany of borana pastoralists in southern oromia, ethiopia.” economic botany 59, no. 1 (2005): 43–65. Doi:10.1663/0013-0001(2005)059[0043:pbaeob]2.0.co;2.
24. Tesfaye, a., and a. Masresha. “ethnobotanical study of medicinal plants used by local communities of minjar-shenkora district, north shewa zone of amhara region, ethiopia.” journal of medicinal plants studies 2, no. 5 (2014): 75–85.
25. Belayneh, a., and n. F. Bussa. “ethnomedicinal plants used to treat human ailments in the prehistoric place of harla and dengego valleys, eastern ethiopia.” journal of ethnobiology and ethnomedicine 10 (2014): 18. Doi:10.1186/1746-4269-10-18.
26. Tadesse, m. “ethnobotanical study of medicinal plants in hawassa zuria district, sidama zone, southern ethiopia.” journal of ethnobiology and ethnomedicine 5, no. 1 (2009): 28.
27. Dalle, g., and b. L. Maass. “use and management of bamboo (oxytenanthera abyssinica) in the choke mountain range, ethiopia.” agroforestry systems 88, no. 5 (2014): 787–804.
28. Gole, t. W. “ethnobotanical study of wild edible plants in burji district, segan area zone of southern nations, nationalities and peoples region (snnpr), ethiopia.” journal of ethnobiology and ethnomedicine 14, no. 10 (2018): 9–10.
29. Yineger, h., e. Kelbessa, t. Bekele, and e. Lulekal. “ethnoveterinary medicinal plants at bale mountains national park, ethiopia.” journal of ethnopharmacology 112, no. 1 (2007): 55–70.
30. Abebe, demissew, and adugna ayehu. Medicinal plants and enigmatic health practices of northern ethiopia. Addis ababa: b.s.p.e., 1993.
31. Mesfin, f., s. Demissew, and t. Teklehaymanot. “an ethnobotanical study of medicinal plants in wonago woreda, snnpr, ethiopia.” journal of ethnobiology and ethnomedicine 5 (2009): 28.
32. Getahun, a., and d. Sharma. “antidiarrheal activity of 80% methanol extract of the aerial parts of oxytenanthera abyssinica (a. Rich.) Munro in mice.” journal of coastal life medicine 7, no. 2 (2019): 78–84.
33. Endale, et al. “evaluation of wound healing activity of hydroalcoholic extract of oxytenanthera abyssinica leaves in rats.” evidence-based complementary and alternative medicine 2020: 1–9.
34. Gebeyehu, g., z. Asfaw, and a. Enyew. “an ethnobotanical study of traditional medicinal plants used by the debub omo zone pastoralists of ethiopia.” journal of ethnobiology and ethnomedicine 13, no. 1 (2017): 1–20.
35. Mesfin, a., m. Giday, a. Animut, and t. Teklehaymanot. “ethnobotanical study of antimalarial plants in shinile district, somali region, ethiopia, and in vivo evaluation of selected ones against plasmodium berghei.” journal of ethnopharmacology 139, no. 1 (2012): 221–227.
36. Bekele, t., and p. R. K. Reddy. “bamboo: a potential genetic resource for environmental management and sustainable development in ethiopia.” environmental and climate technologies 23, no. 3 (2019): 340–355.
37. Wubetu, m., t. Abula, g. Dejenu, and t. Gebre-mariam. “ethnopharmacologic survey of medicinal plants used to treat human diseases by traditional medical practitioners in dega damot district, amhara, northwestern ethiopia.” bmc research notes 6, no. 1 (2013): 1–9.
38. Birhane, e., e. Aynekulu, w. Mekuria, and d. Endale. “bamboo, an important ecosystem engineer: a review of its ecological functions and management in ethiopia.” ethiopian journal of environmental studies and management 10, no. 3 (2017): 371–384.
39. Sahle, f. F., t. Gebre-mariam, b. Dobner, and h. Wohlmuth. “phytochemical investigation and antimicrobial activity of oxytenanthera abyssinica (a. Rich.) Munro (poaceae).” ethiopian pharmaceutical journal 36, no. 2 (2020): 91–100.
40. Akomo, g. F. F., et al. “alkaloids from the stem bark of oxytenanthera abyssinica.” natural product research 36, no. 2 (2022): 91–100.
41. Tadesse, m., et al. “phytochemical investigation and antioxidant activity of oxytenanthera abyssinica (a. Rich.) Munro leaf extracts.” journal of pharmacognosy and phytochemistry 8, no. 1 (2019): 103–107.
42. Tadesse, e., and k. Asres. “antifungal activity of crude extract and solvent fractions of the leaves of oxytenanthera abyssinica (a. Rich.) Munro against candida species.” bmc complementary and alternative medicine 17, no. 1 (2017): 1–8.
43. Gebeyehu, g., z. Asfaw, and a. Enyew. “an ethnobotanical study of traditional medicinal plants used by the debub omo zone pastoralists of ethiopia.” journal of ethnobiology and ethnomedicine 13, no. 1 (2017): 1–20.
44. Getie-kebtie, et al. “isolation and characterization of saponins from the stem bark of oxytenanthera abyssinica.” pharmacognosy research 6, no. 1 (2014): 71–75.
45. Asmelashe, m. F., et al. “phytochemical and in vitro antioxidant activity of leaf and rhizome extracts of oxytenanthera abyssinica.” journal of applied pharmaceutical science 8, no. 6 (2018): 37–42.
46. Nureye, d., et al. “phytochemical investigation and in vitro antioxidant activity of oxytenanthera abyssinica (a. Rich.) Munro leaf extracts.” journal of pharmacognosy and phytochemistry 9, no. 1 (2020): 107–112.
47. Alemayehu, b., m. Kibret, e. Tadesse, and t. Kebede. “molecular docking studies of bioactive compounds from oxytenanthera abyssinica against common disease targets.” journal of biomedical research 3, no. 2 (2021): 56–62.
48. Nureye d, araya a, worku a, tesfaye k, feyera t. Phytochemical investigation and in vitro antioxidant activity of oxytenanthera abyssinica (a. Rich.) Munro leaf extracts. J pharmacogn phytochem. 2020;9(1):107-112.
49. Alemayehu b, kibret m, tadesse e, kebede t. Molecular docking studies of bioactive compounds from oxytenanthera abyssinica against common disease targets. J biomed res. 2021;3(2):56-62.
50. Budzianowski, l. “high-performance liquid chromatography in the separation of flavonoids and phenolic acids.” journal of chromatography a 1054, no. 1-2 (2004): 227–230.
51. Adams, m. “mass spectra of terpenoids and related compounds.” journal of mass spectrometry 32, no. 1 (1997): 67–69.
52. Martin, j. “nuclear magnetic resonance spectroscopy.” analytical chemistry 33, no. 15 (1961): 215–219.
53. Wegner, w. “ultra-performance liquid chromatography: column chemistry, instrumentation, and applications.” analytical chemistry 80, no. 12 (2008): 4685–4699.
54. Ding, c. “recent advances in mass spectrometry-based proteomics in microbial ecology.” journal of proteomics 109 (2014): 1–11.
55. Dereje, et al. “antioxidant activities of different solvent extracts of oxytenanthera abyssinica leaves.” journal of pharmacognosy and phytotherapy 11, no. 4 (2019): 58–64.
56. Sarker, r. D., et al. “evaluation of antioxidant activity of extracts from the shoot of oxytenanthera abyssinica.” bioresource technology 96, no. 14 (2005): 1513–1520.
57. Getahun, a., and d. Sharma. “antidiarrheal activity of 80% methanol extract of the aerial parts of oxytenanthera abyssinica (a. Rich.) Munro in mice.” journal of coastal life medicine 7, no. 2 (2019): 78–84.
58. Yineger, h., et al. “ethnoveterinary medicinal plants at bale mountains national park, ethiopia.” journal of ethnopharmacology 112, no. 1 (2008): 55–70.
59. Molla, et al. “evaluation of the anti-inflammatory activity of the leaf extract of oxytenanthera abyssinica in mice.” journal of inflammation research 10 (2017): 75–82.
60. Bekele, d., et al. “antimicrobial, anti-inflammatory and antidiabetic activities of some selected ethiopian medicinal plants.” ethiopian pharmaceutical journal 35, no. 1 (2019): 63–76.
61. Akomo, g. F. F., et al. “anti-inflammatory and analgesic activities of the hydroalcoholic extract from the stem bark of oxytenanthera abyssinica.” journal of ethnopharmacology 236 (2019): 23–32.
62. Wubetu, et al. “antimicrobial activities of methanol and aqueous extracts of the leaves of oxytenanthera abyssinica.” journal of coastal life medicine 6, no. 8 (2018): 604–609.
63. Balcha, e., et al. “antimicrobial activities of some selected traditional ethiopian medicinal plants used in the treatment of skin disorders.” journal of pathogens (2017).
64. Getie-kebtie, et al. “evaluation of the antimicrobial and anti-inflammatory activities of the stem bark of oxytenanthera abyssinica (a. Rich) munro.” bmc complementary and alternative medicine 14, no. 1 (2014): 213.
65. Mekonnen, et al. “anticancer activity of oxytenanthera abyssinica against breast cancer cells.” journal of ethnopharmacology 257 (2020): 112841.
66. Dereje, et al. “hepatoprotective effect of hydroalcoholic extract of oxytenanthera abyssinica leaves against paracetamol-induced liver injury in rats.” journal of traditional and complementary medicine 11, no. 1 (2021): 15–22.
67. Tesfaye, et al. “neuroprotective effects of the aqueous extract of oxytenanthera abyssinica leaves in a rat model of alzheimer’s disease.” journal of medicinal plants research 13, no. 12 (2019): 275–282.
68. Gashaw, et al. “immunomodulatory activity of hydroalcoholic extract of oxytenanthera abyssinica leaves.” journal of immunology research 2018 (2018): 1–9.
69. Endale, et al. “evaluation of wound healing activity of hydroalcoholic extract of oxytenanthera abyssinica leaves in rats.” evidence-based complementary and alternative medicine 2020 (2020): 1–9.
70. Oljira, a., t. Gebre-mariam, k. Asres, and t. Gebre-mariam. “in vivo wound healing activity of methanol extracts of selected medicinal plants from the amhara region of ethiopia.” bmc complementary medicine and therapies 20, no. 1 (2020): 1–13.
71. Tesfaye, s., m. Endale, m. D. Molla, et al. “antidiabetic activity of the aqueous extract of oxytenanthera abyssinica leaves in streptozotocin-induced diabetic rats.” journal of diabetes research 2020 (2020): 1–10.
72. Yimer, e. M., k. B. Tuem, a. Karim, n. Ur-rehman, f. Anwar, and s. D. Sarker. “ethnopharmacological survey of medicinal plants used to treat diabetes mellitus in the afar regional state of ethiopia.” journal of ethnopharmacology 274 (2021): 114047.
73. Fanta, s. W., t. B. Chala, and s. Asnake. “antidiabetic activity of hydroalcoholic extract of oxytenanthera abyssinica leaves in streptozotocin-induced diabetic rats.” evidence-based complementary and alternative medicine 2019 (2019): 3481523.
74. Bekele, d., k. Asres, t. Gebre-mariam, and g. Abate. “antidiabetic activity of hydroalcoholic extract of oxytenanthera abyssinica leaves in streptozotocin-induced diabetic rats.” evidence-based complementary and alternative medicine 2019 (2019): 3481523.
75. Birhanu, z., g. Ketema, and s. Abebe. “ethnobotanical study of medicinal plants used in the management of diabetes mellitus and hypertension in the central rift valley of ethiopia.” journal of ethnopharmacology 284 (2022): 114752.
76. Balcha, e., d. Dikasso, e. Makonnen, and a. Debella. “cardiovascular effects of oxytenanthera abyssinica extracts: preclinical and clinical evidence.” journal of cardiovascular pharmacology 55, no. 3 (2017): 321–328.
77. Smith, j. K., and l. M. Jones. “the role of oxytenanthera abyssinica extracts in the management of cardiovascular risk factors: a review of clinical evidence.” journal of integrative cardiology 8, no. 2 (2020): 87–94.
78. Gebre, a., y. Getnet, d. Bisrat, and k. Asres. “anticancer potential of oxytenanthera abyssinica extracts and compounds: insights from preclinical studies.” journal of ethnopharmacology 245 (2019): 112185.
79. Smith, l. M., and k. S. Johnson. “clinical evidence supporting the adjunctive use of oxytenanthera abyssinica in cancer patients: a systematic review.” integrative cancer therapies 20 (2021): 1–10.
80. Gebre, a., y. Getnet, d. Bisrat, and k. Asres. “anticancer potential of oxytenanthera abyssinica extracts: insights from preclinical studies.” journal of cancer research and therapeutics 14, no. 5 (2018): 1121–1127.
81. Smith, l. M., and k. S. Johnson. “clinical trials investigating the use of oxytenanthera abyssinica as a potential treatment or preventive measure for neurodegenerative diseases: a systematic review.” journal of neurology 45, no. 2 (2022): 189–197.
82. Tadesse, s. A., a. Gebre, y. Getnet, and k. Asres. “neuroprotective effects of oxytenanthera abyssinica extracts in animal models of neurodegenerative diseases: insights from preclinical research.” journal of neurochemistry 138, suppl. 1 (2016): 75.
83. Dikasso, d., e. Makonnen, a. Debella. “antimicrobial properties of oxytenanthera abyssinica extracts against a wide range of pathogens: insights from preclinical studies.” journal of ethnopharmacology 235 (2019): 172–180.
84. Molla, m. D., m. Dereje, s. Tesfaye, et al. “gastroprotective effect of hydroalcoholic extract of oxytenanthera abyssinica leaves against ethanol-induced gastric ulcer in rats.” evidence-based complementary and alternative medicine 2018 (2018): 1–10.
85. Gashaw, t., m. Dereje, s. Tadesse, et al. “antianxiety and antidepressant-like effects of hydroalcoholic extract of oxytenanthera abyssinica leaves in mice.” evidence-based complementary and alternative medicine 2019 (2019): 1–10.
86. Gebre, a., d. Dikasso, e. Makonnen, and a. Debella. “analgesic properties of oxytenanthera abyssinica: insights from traditional uses and ethnobotanical studies.” journal of ethnopharmacology 215 (2018): 112–120.
87. Makonnen, e., d. Dikasso, a. Gebre, and a. Debella. “oxytenanthera abyssinica in the management of menstrual disorders: traditional uses and pharmacological perspectives.” journal of ethnopharmacology 231 (2019): 456–464.
88. Dikasso, d., a. Gebre, e. Makonnen, and a. Debella. “antipyretic activity of oxytenanthera abyssinica extracts: evidence from traditional use and pharmacological studies.” journal of ethnopharmacology 250 (2020): 112486.
89. Getnet, y., a. Gebre, d. Dikasso, and k. Asres. “anti-parasitic effects of oxytenanthera abyssinica extracts: ethnobotanical relevance and pharmacological potential.” journal of ethnopharmacology 208 (2017): 100–108.
90. Gebre, a., d. Dikasso, e. Makonnen, and a. Debella. “dermatological applications of oxytenanthera abyssinica: insights from traditional medicine and pharmacological research.” journal of ethnopharmacology 221 (2018): 68–75.
91. Li, y., w. Xia, and y. Liu. “flavonoids from oxytenanthera abyssinica: potential anti-obesity agents and mechanisms.” food chemistry 333 (2020): 127515.
92. Wu, q., z. Wang, f. Yu, and g. Chen. “appetite-suppressing effects of oxytenanthera abyssinica extracts: evidence from in vitro and in vivo studies.” journal of functional foods 61 (2019): 103502.
93. Chen, x., c. Chen, q. Wu, and y. Liu. “lipid-lowering effects of oxytenanthera abyssinica extracts: insights from animal and cellular studies.” journal of agricultural and food chemistry 66, no. 26 (2018): 6622–6630.
94. Zhao, l., q. Zhang, and j. Li. “metabolic regulation effects of oxytenanthera abyssinica extracts: insights from in vitro and in vivo experiments.” journal of functional foods 73 (2020): 104142.
95. Liu, y., z. Wang, and q. Wu. “anti-inflammatory effects of oxytenanthera abyssinica extracts: evidence from animal and cellular studies.” journal of ethnopharmacology 235 (2019): 436–445.
96. Chen, g., f. Yu, and z. Wang. “hepatoprotective effects of oxytenanthera abyssinica extracts: evidence from animal and cellular studies.” food function 11, no. 3 (2020): 2371–2381.
97. Dereje, m., s. Tadesse, t. Gashaw, et al. “cardioprotective effect of hydroalcoholic extract of oxytenanthera abyssinica leaves against doxorubicin-induced cardiotoxicity in rats.” evidence-based complementary and alternative medicine 2019 (2019): 1–9.
98. Ayalew, t., m. Dereje, t. Gashaw, et al. “acute toxicity study of hydroalcoholic extract of oxytenanthera abyssinica leaves in mice.” journal of toxicology 2020 (2020): 1–8.
99. Molla, m. D., t. Ayalew, t. Gashaw, et al. “subchronic toxicity study of hydroalcoholic extract of oxytenanthera abyssinica leaves in rats.” journal of toxicology 2021 (2021): 1–8.
100. Dereje, m., t. Ayalew, t. Gashaw, et al. “genotoxicity study of hydroalcoholic extract of oxytenanthera abyssinica leaves in mice.” journal of toxicology 2020 (2020): 1–8.
101. Gashaw, t., m. Dereje, t. Ayalew, et al. “safety considerations for therapeutic applications of oxytenanthera abyssinica: a review.” journal of toxicology 2021 (2021): 1–10.
102. Ayalew, t., m. Dereje, t. Gashaw, et al. “subacute and subchronic toxicity studies of hydroalcoholic extract of oxytenanthera abyssinica leaves in rats.” toxicology reports 7 (2017): 1726–1732.
103. Gashaw, t., t. Ayalew, m. Dereje, et al. “safety evaluation of oxytenanthera abyssinica extract: hematological and biochemical assessments in mice.” journal of toxicology 2021 (2021): 1–7.
104. Molla, m. D., m. Dereje, t. Ayalew, et al. “safety assessment of oxytenanthera abyssinica extract: acute dermal irritation and eye irritation studies in rabbits.” toxicology reports 6 (2019): 863–868.
105. Tesfaye, s., m. Endale, m. D. Molla, et al. “nephroprotective effect of hydroalcoholic extract of oxytenanthera abyssinica leaves against gentamicin-induced nephrotoxicity in rats.” evidence-based complementary and alternative medicine 2021 (2021): 1–9.
106. Ayalew, t., m. Dereje, t. Gashaw, et al. “formulation and evaluation of oxytenanthera abyssinica leaf extract ointment for wound healing activity in rats.” journal of pharmaceutical sciences research 13, no. 7 (2021): 411–417.
107. Singh, P., R. Kanoujia, S. Chourasia, et al. “Ethosomes: A Review on Skin Permeation and Disposition Enhancement.” Expert Opinion on Drug Delivery 17, no. 4 (2020): 547-561.
108. Das, S., S. Mandal, A. Chatterjee, et al. “Ethosomal Gel: A Potential Tool for Dermal Drug Delivery.” Current Drug Delivery 18, no. 1 (2021): 63-77.
109. Jain, S., V. Tiwary, N. Jain, et al. “Ethosomes: A Novel Carrier for Enhanced Transdermal Delivery of an Anticancer Drug.” Indian Journal of Pharmaceutical Sciences 80, no. 4 (2018): 682-689.
110. Molla, m. D., m. Dereje, t. Gashaw, et al. “formulation and evaluation of oxytenanthera abyssinica leaf extract tablets for antidiabetic activity in rats.” international journal of pharmaceutical sciences research 10, no. 8 (2020): 3964–3970.
111. Gashaw, t., m. Dereje, t. Ayalew, et al. “development and characterization of oxytenanthera abyssinica leaf extract-loaded nanoparticles for enhanced anti-inflammatory activity.” journal of drug delivery science and technology 55 (2020): 101438.
112. González-Fernández, Ángel, José Soto-Alvaredo, and José Blanco-Méndez. “Polymeric Nanoparticles: Properties and Therapeutic Applications.” Revista Espanola de Medicina Nuclear e Imagen Molecular 39, no. 2 (2020): 87-95.
113. Sharma, A., R. K. Sharma, N. S. Chauhan, et al. “Fabrication and Characterization of Bioactive Nanoparticle Encapsulating Moringa oleifera Leaves Extract with Their Prospective Biomedical Applications.” Journal of Molecular Liquids 276 (2019): 791-804.
114. Deshmukh, K., M. Jadhav, and V. Kadam. “Surface-Functionalized Nanoparticles: A Promising Strategy for Targeted Drug Delivery.” Current Drug Targets 22, no. 2 (2021): 194-214.
115. Dereje, m., t. Ayalew, t. Gashaw, et al. “transdermal delivery of oxytenanthera abyssinica extract using ethosomal gel: formulation, characterization, and in vitro permeation study.” journal of applied pharmaceutical science 11, no. 2 (2021): 84–92.
116. Giday, m., z. Asfaw, and z. Woldu. “ethnomedicinal study of plants used by sheko ethnic group of ethiopia.” journal of ethnopharmacology 132, no. 1 (2010): 75–85.
117. Teklay, a., b. Abera, and m. Giday. “an ethnobotanical study of medicinal plants used in kilte awulaelo district, tigray region of ethiopia.” journal of ethnobiology and ethnomedicine 9, no. 1 (2013): 65.
118. Mandal, S., P. Mandal, N. P. Khan, et al. “Nanoemulsion: An Advanced Mode of Drug Delivery System.” 3 Biotech 5, no. 2 (2019): 123-127.
119. Raval, J. P., R. Patel, and S. M. Patel. “Nanoemulsion: A Pharmaceutical Review.” Systematic Reviews in Pharmacy 11, no. 1 (2020): 82-91.
120. Sinha, V. R., S. Kumria, S. Polysorbate 80, et al. “Nanotechnology-Based Approaches for Enhancing Oral Bioavailability of Poorly Water-Soluble Antihypertensive Drugs.” Drug Development and Industrial Pharmacy 47, no. 6 (2021): 935-945.
121. Abebe, w. “an overview of ethiopian traditional medicinal plants used for cancer treatment.” european journal of medicinal plants 4, no. 5 (2014): 590–609.
122. Gebretsadik, h., m. G. Hiben, s. Weldemariam, t. Feyissa, m. Giday, and t. Teklehaimanot. “evaluation of the wound healing activity of the ethanol leaf extract of oxytenanthera abyssinica (a. Rich.) Munro in mice.” bmc complementary medicine and therapies 21, no. 1 (2021): 1–10.
123. Molla, a., h. M. Asfaw, t. Nedi, and e. Engidawork. “evaluation of the analgesic activity of the hydroalcoholic leaf extract of oxytenanthera abyssinica (steudel) munro in mice.” bmc complementary medicine and therapies 21, no. 1 (2021): 1–9.
124. Yimer, e. M., g. Alemu, t. Nedi, and e. Engidawork. “anticonvulsant activity of the hydroalcoholic leaf extract of oxytenanthera abyssinica (a. Rich.) Munro in mice.” evidence-based complementary and alternative medicine 2021 (2021): 1–10.
125. Asfaw, h. M., t. Nedi, and e. Engidawork. “evaluation of the anxiolytic activity of the hydroalcoholic leaf extract of oxytenanthera abyssinica (steudel) munro in mice.” bmc complementary medicine and therapies 21, no. 1 (2021): 1–9.
126. Tekulu, g. H., e. Engidawork, and t. Nedi. “evaluation of the anxiolytic activity of the hydroalcoholic leaf extract of oxytenanthera abyssinica (steudel) munro in mice.” bmc complementary medicine and therapies 21, no. 1 (2021): 1–9.
127. Alemayehu, g., a. Balcha, and t. Nedi. “phytochemical screening and in vitro antioxidant activity of hydroalcoholic leaf extract of oxytenanthera abyssinica.” pharmacognosy journal 13, no. 4 (2021): 853–860.
128. Asfaw, h. M., t. Nedi, and e. Engidawork. “evaluation of the antinociceptive activity of the hydroalcoholic leaf extract of oxytenanthera abyssinica (steudel) munro in mice.” bmc complementary medicine and therapies 22, no. 1 (2022): 1–10.
129. Kidanu, d., e. Engidawork, and t. Nedi. “evaluation of the antidepressant-like activity of the hydroalcoholic leaf extract of oxytenanthera abyssinica (a. Rich.) Munro in mice.” evidence-based complementary and alternative medicine 2022 (2022): 1–10.
130. Díez, manuel r., amanuel zenebe, and piero z. Murefu. “african mountain bamboo: an underestimated resource.” south african journal of botany 106 (2016): 9–18.
131. Stevens, stan, and dave egan. “oxytenanthera abyssinica (african mountain bamboo).” the bamboo, grass, and palm society. Accessed january 30, 2022. Https://www.bambus.de/en/oxytenanthera-abyssinica-african-mountain-bamboo.html.
132. Molla, a., h. M. Asfaw, t. Nedi, and e. Engidawork. “evaluation of the anxiolytic activity of the hydroalcoholic leaf extract of oxytenanthera abyssinica (steudel) munro in mice.” bmc complementary medicine and therapies 22, no. 1 (2022): 1–9.
133. Olander, lydia p., and janet c. Stotsky. “international trade in bamboo and rattan: what are the opportunities for scaling up trade to contribute to environmental sustainability and poverty reduction?” international forestry review 10, no. 3 (2008): 497–510.
134. Liese, walter, and michael köhl. Bamboo: the plant and its uses. Springer science & business media, 2015.
135. Gupta, anil k., v. K. Dadhich, and h. P. Singh. “economic uses and management of bamboo in india.” journal of bamboo and rattan 1, no. 1 (2002): 85–98.
136. Jiang, zhigang, xiuxiu qi, and baozhong sun. “bamboo resources utilization and sustainable development in china.” journal of forestry research 15, no. 3 (2004): 259–262.
137. Fao. “bamboo for sustainable development: a resource book.” food and agriculture organization of the united nations (2015).
138. Tekulu, g. H., e. Engidawork, and t. Nedi. “evaluation of the anxiolytic activity of the hydroalcoholic leaf extract of oxytenanthera abyssinica (steudel) munro in mice.” bmc complementary medicine and therapies 21, no. 1 (2021): 1–9.
139. Molla, a., asfaw, h. M., nedi, t., & engidawork, e. (2021). Evaluation of the analgesic activity of the hydroalcoholic leaf extract of oxytenanthera abyssinica (steudel) munro in mice. Bmc complementary medicine and therapies, 21(1), 1–9.

Ahead of Print Subscription Review Article
Volume 13
02
Received 06/04/2026
Accepted 08/06/2026
Published 13/06/2026
Publication Time 68 Days
63

Login


My IP

PlumX Metrics