Application of Metabolomics in Pharmacognosy

Year : 2025 | Volume : 12 | Issue : 03 | Page : 01 07
    By

    V. Basil Hans,

  1. Research Professor, Research Professor, Srinivas University, Mangalore, Karnataka, India

Abstract

In the field of pharmacognosy, the identification, quality control, and bioactivity evaluation of medicinal plants and natural products have become significantly more effective thanks to the development of a strong tool known as metabolomics, which is the complete study of small-molecule metabolites in biological systems. Metabolomics offers more in-depth insights into phytochemical composition, plant metabolism, and the mechanisms that underlie medicinal benefits. It does this by enabling high-throughput analysis and thorough metabolic profiling. The utilization of this methodology facilitates the identification of novel bioactive components, contributes to the standardization of herbal medicines, and improves the comprehension of the interactions between plants and their environments. Its application in contemporary pharmacognostic research is further strengthened by the incorporation of other omics technologies and chemometric methods. This article provides an overview of the most recent developments, techniques, and potential future applications of metabolomics within the context of the ever-changing field of pharmacognosy.

Keywords: Pharmaceutical research, pharmacognostic research, biological system, methodological techniques, efficacy of herbal remedies.

[This article belongs to Research & Reviews: A Journal of Pharmacognosy ]

How to cite this article:
V. Basil Hans. Application of Metabolomics in Pharmacognosy. Research & Reviews: A Journal of Pharmacognosy. 2025; 12(03):01-07.
How to cite this URL:
V. Basil Hans. Application of Metabolomics in Pharmacognosy. Research & Reviews: A Journal of Pharmacognosy. 2025; 12(03):01-07. Available from: https://journals.stmjournals.com/rrjopc/article=2025/view=225143


References

  1. F. Gomez-Casati, D., I. Zanor, M., & V. Busi, M., 2013. Metabolomics in Plants and Humans: Applications in the Prevention and Diagnosis of Diseases. ncbi.nlm.nih.gov
  2. Puri, S., Sahal, D., & Sharma, U., 2021. A conversation between hyphenated spectroscopic techniques and phytometabolites from medicinal plants. ncbi.nlm.nih.gov
  3. Lin, C., Tian, Q., Guo, S., Xie, D., Cai, Y., Wang, Z., Chu, H., Qiu, S., Tang, S., & Zhang, A., 2024. Metabolomics for Clinical Biomarker Discovery and Therapeutic Target Identification. ncbi.nlm.nih.gov
  4. Hu S, Liu C, Liu X. Innovative application of metabolomics on bioactive ingredients of foods. Foods. 2022 Sep 23;11(19):2974.
  5. Marchev AS, Vasileva LV, Amirova KM, Savova MS, Balcheva-Sivenova ZP, Georgiev MI. Metabolomics and health: from nutritional crops and plant-based pharmaceuticals to profiling of human biofluids. Cellular and Molecular Life Sciences. 2021 Oct;78(19-20):6487-503.
  6. Bujak R, Struck-Lewicka W, Markuszewski MJ, Kaliszan R. Metabolomics for laboratory diagnostics. Journal of pharmaceutical and biomedical analysis. 2015 Sep 10;113:108-20.
  7. Rangel-Huerta OD, Gil A. Nutrimetabolomics: an update on analytical approaches to investigate the role of plant-based foods and their bioactive compounds in non-communicable chronic diseases. International journal of molecular sciences. 2016 Dec 9;17(12):2072.
  8. Putri SP, Yamamoto S, Tsugawa H, Fukusaki E. Current metabolomics: technological advances. Journal of bioscience and bioengineering. 2013 Jul 1;116(1):9-16.
  9. Zhang J, Sun M, Elmaidomy AH, Youssif KA, Zaki AM, Kamal HH, Sayed AM, Abdelmohsen UR. Emerging trends and applications of metabolomics in food science and nutrition. Food & function. 2023;14(20):9050-82.
  10. Fraga-Corral M, Carpena M, Garcia-Oliveira P, Pereira AG, Prieto MA, Simal-Gandara J. Analytical metabolomics and applications in health, environmental and food science. Critical Reviews in Analytical Chemistry. 2022 May 19;52(4):712-34.

Regular Issue Subscription Review Article
Volume 12
Issue 03
Received 15/08/2025
Accepted 28/08/2025
Published 29/08/2025
Publication Time 14 Days


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