Garcinia cambogia Use of Weight Loss and Hepatotoxicity: A Review

Year : 2025 | Volume : 12 | Issue : 02 | Page : 08 14
    By

    Arun kumar Pal,

  • Swarnima pandey,

  1. Professor, Apex College of Pharmacy, Bilaspur, Rampur, Uttar Pradesh, India
  2. Principal, Apex College of Pharmacy, Bilaspur, Rampur, Uttar Pradesh, India

Abstract

A complex disorder of hunger control and energy metabolism driven by certain biological variables is obesity. This study aims to evaluate the applications of Garcinia cambogia products for appetite suppression and fat burning. This little fruit, which looks a lot like a pumpkin, is marketed and used most frequently these days as a weight-loss supplement. Research has demonstrated that the fruit rind’s main organic acid component, (−)-hydroxycitric acid (HCA), and the extracts both have anti-obesity properties that reduce food intake and body fat gain by controlling satiety-related serotonin levels, increasing fat oxidation, and lowering de novo lipogenesis. HCA significantly inhibits adenosine triphosphate-citrate lyase, a catalyst that transforms citrate into acetyl-coenzyme A, which is necessary for the creation of fatty acids, cholesterol, and triglycerides.

Keywords: Weight loss, HCA, Anti-obesity, Anticancer activity, Garcinia cambogia.

[This article belongs to Research & Reviews: A Journal of Pharmacognosy ]

How to cite this article:
Arun kumar Pal, Swarnima pandey. Garcinia cambogia Use of Weight Loss and Hepatotoxicity: A Review. Research & Reviews: A Journal of Pharmacognosy. 2025; 12(02):08-14.
How to cite this URL:
Arun kumar Pal, Swarnima pandey. Garcinia cambogia Use of Weight Loss and Hepatotoxicity: A Review. Research & Reviews: A Journal of Pharmacognosy. 2025; 12(02):08-14. Available from: https://journals.stmjournals.com/rrjopc/article=2025/view=208656


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Regular Issue Subscription Review Article
Volume 12
Issue 02
Received 25/03/2025
Accepted 15/04/2025
Published 24/04/2025
Publication Time 30 Days
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