Phytopharmacognostic Study Development And Assessment Of Datura Stramonium

Year : 2025 | Volume : 12 | Issue : 02 | Page : 33 39
    By

    Mohd. Wasiullah,

  • Piyush Yadav,

  • Aratee Patel,

  1. Principal, Dept. of Pharmacy, Prasad Institute of Technology, Jaunpur, Uttar Pradesh, India
  2. Academic Head, Dept. of Pharmacy, Prasad Institute of Technology, Jaunpur, Uttar Pradesh, India
  3. Scholar, Dept. of Pharmacy Prasad Institute of Technology, Jaunpur, Uttar Pradesh, India

Abstract

Daturastrontium, a member of the Solanaceae family, is widely known for its medicinal and toxicological significance. Native to Asia and the Americas, it has been utilized for both spiritual rituals and traditional medicine due to its potent psychoactive and narcotic properties. Historically, it has been employed to treat conditions such as asthma, rheumatism, and inflammation, but its misuse, especially in religious contexts and recreationally, often leads to toxic effects like hallucinations, confusion, and memory loss. The plant contains tropane alkaloids, including atropine, scopolamine, and hyoscyamine, which act on the central nervous system, making it both a valuable medicinal herb and a dangerous toxicant. Despite some therapeutic benefits, such as antispasmodic and bronchodilating effects, its toxic potential overshadows its medicinal uses. Extreme caution is required when handling or using Datura stramonium due to the risk of poisoning, particularly from ingestion.

Keywords: Datura stramonium, Phytochemistry, Ethnopharmacology, Ethanomedical uses, hallucinations.

[This article belongs to Research & Reviews: A Journal of Pharmacognosy ]

How to cite this article:
Mohd. Wasiullah, Piyush Yadav, Aratee Patel. Phytopharmacognostic Study Development And Assessment Of Datura Stramonium. Research & Reviews: A Journal of Pharmacognosy. 2025; 12(02):33-39.
How to cite this URL:
Mohd. Wasiullah, Piyush Yadav, Aratee Patel. Phytopharmacognostic Study Development And Assessment Of Datura Stramonium. Research & Reviews: A Journal of Pharmacognosy. 2025; 12(02):33-39. Available from: https://journals.stmjournals.com/rrjopc/article=2025/view=208445


References

  1. Fornoi J, Nunez-Farfan Evolutionary ecology of Daturastramonium: genetic variation and costs for tolerance to defoliation. Evolution. 2000; 54(3): 789-797 https://doi.org/10.1111/j.0014-3820.2000.tb00080.x .
  2. Luna-Cavazos M, Bye Phytogeographic analysis of the genus Datura (Solanaceae) in continental Mexico. Rev MexBiodivers. 2011; 82:(3) 977-988.
  1. Berkov S, Zayed R, Doncheva Alkaloid patterns in some varieties of Datura Stramonium. Fitoterapia. 2006; 77(3): 179-182 https://doi.org/10.1016/j.fitote.2006.01.002
  2. Ajungla L, Patil PP, Barmukh RB, Nikam Influence of biotic and abiotic elicitors on accumulation of hyoscyamine and scopolamine in root cultures of Daturametel L.Indian J Biotechnol. 2009; 8(3): 317-322.
  1. Dessanges JF. A history of nebulization. J Aerosol Med. 2001 Spring;14(1):65-71. doi: 10.1089/08942680152007918.
  1. Diker D, Markovitz D, Rothman M, Sendovski U. Coma as a presenting sign of Datura Stramonium seed tea Eur J Intern Med. 2007; 18(4); 336-338 https://doi.org/10.1016/j.ejim.2006.09.035 .
  2. Norton S. Toxic effects of plants. Casarett and Doull’s Toxicology: the basic Science of poisons. 2001:965-76.
  3. Kririkar KR, Basu Indian medicinal plants. 2nd ed. Volume III. Dehradun: International Book Distributors. 1999: 1783-1787.
  4. Gaire BP . Monograph on DaturaStramonium. Kaski, Nepal: Pokhara University 2008: 1-114
  5. Khare Indian medicinal plants. Delhi: Rajkamal Electric Press. 2007: 203 Preissel U, Preissel HG. Brugmansia and Datura: Angel’s Trumpets and Thorn Apples. New York: Firefly Books. 2002: 106-129.
  6. Das S, Kumar P, Basu Review article on phytoconstituents and therapeutic potentials of DaturaStramonium Linn. J Drug DelivTher. 2012; 2(3): 4-7.
  7. Joshi Medicinal plants. New Delhi: Oxford and IBH Publishing Co. Pvt. Ltd. 2000: 370-371.
  8. Rajbhandari Ethnobotany of Nepal. Kathmandu: Kishor Offset Press Private Limited. 2001: 142-143
  1. Egharevba RKA, Ikhatua MI. Ethno-medical uses of plants in the treatment of various skin diseases in Ovia North Eat, Edo State, Res J ArgicBiol Sci. 2008; 4(1): 58- 64.
  2. Gorsi MS, Shahzad Medicinal uses of plants with particular reference to the people of Dhirkot, Azad Jammu and Kashmir. Asian J Plant Sci. 2002; 1(3): 222-223.
  1. Hussain F, Badshsh L, Dastagir Folk medicinal uses of some plants of South Waziristan, Pakistan. Pak J Plant Sci. 2006; 12: 27-39.
  2. Jakabova S, Vincze L, Farkas A, Kilar F, Boros B, Felinger Determination of tropane alkaloids atropine and scopolamine by liquid chromatography-mass spectrometry in plant organs of Datura species. J Chromatogr A. 2012; 1232: 295-301.
  3. Berkov S, Pavlov A, Kovatcheva P, Stanimirova P, Philipov Alkaloid spectrum in diploid and tetraploid hairy root cultures of Daturastramonium. Z Naturforsch C. 2003; 58(1-2): 42-46.
  4. Iranbakhsh A, Oshaghi MA, Majd Distribution of atropine and scopolamine in different organs and stages of development in Daturastramonium L. (Solanaceae). Structure and ultrastructure of biosynthesizing cells. ActaBiolCracSer Bot. 2006; 48(1): 13-18.
  5. Li J, Lin B, Wang G, Gao H, Qin Chemical constituents of Daturastramonium seeds. ZhongguoZhong Yao ZaZhi. 2012; 37(3): 319-322. Chinese with abstract in English.
  1. Charpin D, Orehek J, Velardocchio Bronchodilator effects of antiasthmatic cigarette smoke (Daturastramonium). Thorax. 1979; 34(2): 259-261.
  2. Pretorius E, Marx Daturastramonium in asthma treatment and possible effects on prenatal development. Environ ToxicolPharmacol. 2006; 21(3): 331-337.
  1. Kurzbaum A, Simsolo C, Kvasha L, Blum Toxic delirium due to Daturastramonium. Isr Med Assoc J. 2001; 3(7): 538-539.
  2. Hirschmann GS, De Arias A survey of medicinal plants of minas gerais, Brazil. J Ethnopharmacol. 1990; 29(2): 159-172.

Regular Issue Subscription Review Article
Volume 12
Issue 02
Received 14/12/2024
Accepted 07/01/2025
Published 15/04/2025
Publication Time 122 Days


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