Akshata.M. Girase
Bhupendra.M.Mahale
Sulbha.G.Patil
Dr. Sunila. A. Patil
- Research Scholar, Poojya Sane Guruji Vidya Prasarak Mandal’s College of Pharmacy and Research, Maharashtra, India
- Research Scholar, Poojya Sane Guruji Vidya Prasarak Mandal’s College of Pharmacy and Research, Maharashtra, India
- Professor, Poojya Sane Guruji Vidya Prasarak Mandal’s College of Pharmacy and Research, Maharashtra, India
- Professor, Poojya Sane Guruji Vidya Prasarak Mandal’s College of Pharmacy and Research, Maharashtra, India
Abstract
The increasing usage of plant-based medications is mostly due to their lower costs, greater efficacy, and little or nonexistent adverse effects as compared to contemporary medications. To support the claims made about medicinal plants in traditional medicine systems, a great deal of research is being done on them. The Asteraceae family includes the aromatic herb Sphaeranthus indicus. It thrives as a weed in paddy fields and is found throughout India’s lowlands and moist areas. This page summarizes the research that has been done on the pharmacological characteristics of S. indicus by different scientists. The entire plant as well as its anatomical parts have been shown to contain a variety of secondary metabolites, including eudesmanolides, sesquiterpenoids, sesquiterpene lactones, sesquiterpene acids, flavone glycosides, flavonoid C-glycosides, isoflavone glycoside, sterols, sterol glycoside, alkaloids, peptide alkaloids, amino acids, and sugars. The essential oils that were extracted from the flowers and whole plants were studied by several authors, who reported that several monoterpene hydrocarbons, oxygenated monoterpenes, sesquiterpene hydrocarbons, and oxygenated sesquiterpenes were present. The entire plant, its isolated secondary metabolites, and various anatomical parts have been reported to exhibit ovicidal, antifeedant, anthelmintic, antimicrobial, antiviral, macrofilaricidal, larvicidal, analgesic, antipyretic, hepatoprotective, antitussive, wound healing, bronchodilatory, mast cell stabilising activity, anxiolytic, neuroleptic, immunomodulatory, anti-diabetic, antihyperlipidemic and antioxidant, antioxidant, central nervous system depressant, anti-arthritic, nephroprotective, anticonvulsant, and many other activities. Bears the colloquial names Mundi and East Indian globe thistle It is a fragrant herb that spreads. It is native to the Rater area of the Chhindwara District in Madhya Pradesh and may be found in most of the tropical regions of the Garhwal Himalaya that are humid and moist.
Keywords: Sphaeranthus indicus, Aromatic herb, Ovicidal, Antifeedant , Antimicrobial, Immunomodulatory , Antihyperlipidemic , Antioxidant.
[This article belongs to Research & Reviews: A Journal of Pharmacognosy(rrjopc)]
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References
1. Gogate, V.M. (2000) Ayurvedic Pharmacology and Therapeutic Uses of Medicinal Plants (Dravyaganvigyan). Bhartiya Vidya Bhavan, Mumbai.
2. Ramachandran S. Review on Sphaeranthus indicus Linn. (Koṭṭaikkarantai). Pharmacognosy reviews 2013;7(14):157-69.
3. Nadkarni, K. Indian Material Medica (Vol. 1). 3rd edition. Bombay: Popular Prakashan. 2007;1162
4. Hamayun M, Khan SA, Sohn EY, Lee IJ. Folk medicinal knowledge and conservation status of some economically valued medicinal plants of District Swat, Pakistan. Lyonia. 2006 Dec;11(2):101-13.
5. Dhuri, K.D., Vaidya, V.A. and Vaidya, A.D. (2000) Stress and Ayurveda: Selye-Mehata Dialogue in Context of the Current Findings. Journal of the Association of Physicians of India, 48 (4), 428-31.
6. Kirtikar KR, Basu BD. In: Blatter E, Caius JF, Mhaskar KS, editors. Indian Medicinal Plants. 2nd ed., Vol. 2. Allahabad, India: Lalit Mohan Basu; 1981. p. 1346-8.
7. Namrata G. Mahajan*, Manojkumar Z. Chopda, Raghunath T. Mahajan Department of Zoology, KCE’s, Moolji Jaitha College, North Maharashtra University, Jalgaon 425 002, Maharashtra, India, A Review on Sphaeranthus Indicus Linn: Multipotential Medicinal Plant, International Journal of Pharmaceutical Research & Allied Sciences, Volume 4, Issue 3 (2015):48-74
8. Anonymous. The Siddha Formulary of India. Part II. 1st ed. (Tamil version). New Delhi: Department of AYUSH, Ministry of Health and Family Welfare, Government of India; 2011. p. 142-3.
9. Anonymous. The Ayurvedic Pharmacopoeia of India. Part I. Vol. III. New Delhi: Department of ISM and H, Ministry of Health and Family Welfare, Government of India; 2001. p. 127-8.
10. Shakila Ramachandran. Review on Sphaeranthus indicus Linn. (Kot.t.aikkarantai). Pharmacognosy Reviews. 2013, 7(14) PP:157.
11. Galani VJ, Patel BG, Rana DG. Sphaeranthus indicus Linn.: A phytopharmacological review. Int. J Ayurveda Res. 2010; 1(4):247-53.
12. Makhija K, Richard L, Kirti SP, Saleemullah K, Jessy M, Shirwaikar A. Sphaeranthus indicus: A review of its chemical, pharmacological and ethnomedical properties. Int J Pharmacol. 2011; 7(2):171-9.
13. Tiwari BK, Khosa RL. Hepatoprotective and antioxidant effect of Sphaeranthus indicus against acetaminophen induced hepatotoxicity in rats. J Pharm Sci and Res. 2009; 1(2):26-30
14. Galani VJ, Patel BG. Effect of hydroalcoholic extract of Sphaeranthus indicus against experimentally induced anxiety, depression and convulsions in rodents. Int J Ayu Res 2010;1(2):87-92
15. Shirwaikar A, Prabhu KS, Punitha IS. In vitro antioxidant studies of Sphaeranthus indicus (Linn). Indian J Exp Biol 2006;44(12):993-6.
16. Vimalanathan S, Ignacimuthu S, Hudson JB. Medicinal plants of Tamil Nadu (Southern India) are a rich source of antiviral activities. Pharmaceutical Biology, 2009; 47(5):422- 429
17. Nanda BK, Jena J, Rath B, Behera GR. Analgesic and antipyretic activity of whole parts of Sphaeranthus indicus Linn., Journal of Chemical and Pharmaceutical Research. 2009; 1(1): 207-12.
18. Shekhani MS, Shah PM, Yasmin A, Siddiqui R, Perveen S, Khan KM. et al. An immunostimulant sesquiterpene glycoside from Sphaeranthus indicus. Phytochemistry (Oxford). 1990; 29(8):2573-2576.
19. Tiwari A, Saxena RC. Repellent and feeding deterrent activity of Sphaeranthus indicus against Tribolium castaneum (Herbst). Bio Sci Res Bull. 1993; 9(1-2):57- 59
20. Tenpe CR, Upaganlawar AB, Nayak SH, Yeole PG. Effect of Sphaeranthus indicus Linn. on lipid profile in dexamethasone induced rats. Biomed 2008;2(4):400-3
21. Nanda BK, Jena J, Rath B, Behera B. Anti-inflammatory activity of whole parts of S. indicus. Der Pharmacia Lettre. 2010; 2(1):181-88.
22. Srinivasan VM, Jessy KK, Alex AE. Effect of Sphaeranthus indicus Linn. On gentamicin induced acute renal failure in rats. Indian J Pharmacology 2008;40 :71-72.
23. Badgujar LB, Ghosh P, Gaur V, Bodhankar SL. Effect of petroleum ether extract of Sphaeranthus indicus Linn. on complete freunds adjuvant induced arthritis in laboratory rats. Pharmacologyonline 2009;2:281-91.
24. Sharma S, Jalalpure SS, Semwal B, Tandon S, Agarwal N. Anthelmintic activity of the whole plant of Sphaeranthus indius Linn. Int J Ayur Herb Med 2011,4(11);4254-55.
25. Lalla PM, Deshpande AR, Musaddip M, Shahare NH, Ukesh CS. Antimicrobial activity of medicinal plant Sphaeranthus indicus. In: International Conference on Modern Trends in Plant Sciences with Special Reference to the Role of Biodiversity in Conservation, Maharashtra, Amravati. 2005, 96.
26. Singh SK, Saroj K, Tripathi VJ, Singh AK, Singh RH. An antimicrobial principle from sphaeranthus-indicus, Family compositae. Inter J Crude Drug Res. 1988; 26:235-239.
27. Shirode DS, Jain BB, Mahendra CB. Efficacy of Sphaeranthus indicus in the treatment of rifampicin induced hepatotoxicity in rats. Biosci Biotechnol Res Asia 2015;12(2):1487-93.
28. Shirode DS, Jain BB, Mahendra CB. Antiulcer activity of Sphaeranthus indicus against indomethacin, ethanol and six-hour pylorus ligation induced ulcer in rats. Int J Res Ayurvedic Pharma 2015;6 (6):781-2
29. Ayyanara M, Ignacimuthu S. Ethnobotanical survey of medicinal plants commonly used by Kani tribals in Tirunelveli hills of Western Ghats, India, J. Ethnopharmacology. 2011(12); 134(3):851-864.
30. Kirtikar KR, Basu BD. Indian medicinal plant,Vol- II. Allahabad: Lalit Mohan Basu Publication. 1935, 1347-48.
31. Nayak SS, Maity TK, Maiti BC. Antitussive and synergistic effects of sleeping time induced by standard sedatives of Sphaeranthus indicus plant extracts. J Adv Pharm Res. 2010; 1:123-132.
32. Kovendan K, Arivoli S, Maheshwaran R, Baskar K, Vincent S. Larvicidal efficacy of Sphaeranthus indicus, Cleistanthus collinus and Murraya koenigii leaf extracts against filarial vector, Culex quinquefasciatus Say (Diptera: Culicidae). Parasitology Research. 2012; 111(3):1025.
33. Sen SK, Pradhan NB, Behera LM. Ethnomedical plants used against dysuria at Bargarh district in Orissa. Ad Plant Sci. 2001; 14:459-462.
34. Galani VJ, Patel BG. Effect of hydroalcoholic extract of Sphaeranthus indicus against experimentally induced anxiety, depression and convulsions in rodents. Int J Ayurveda Res. 2010; 1:87-92.
35. Sharma S. Sphaeranthus indicus (East Indian globe thistle)-A promising natural remedy for psoriasis. J Am Acad Dermato. 2010; 62(3):131.
36. Aravind KS, Mukund H, Mamathadevi DS. Appraisal of scopolamine-induced antiamnesic effect of Sphaeranthus indicus in mice. Pharmacology online. 2010; 1:443-452.
37. Srinivasan VM, Jessy KK, Alex AE. Effect of Sphaeranthus indicus Linn. On gentamicin induced acute renal failure in rats. Indian J Pharmacol. 2008; 40:71-72.
38. Dhar ML, Dhar MM, Dhawan BN, Mehrotra BN, Ray C. Screening of Indian plants for biological activity: I. Indian J Exp Biol. 1968; 6:232-247.
39. Indian Pharmacopeia (1985) 3(II), Government of India, Ministry of Health, Controller of Publications. New Delhi, India.
40. https://drwakde.com/in/gorakhmundi-capsules-sphaeranthus-indicus.html
41. https://www.exportersindia.com/product-detail/tinefcon-tablets-1866974722.htm
Research & Reviews: A Journal of Pharmacognosy
| Volume | 11 |
| Issue | 01 |
| Received | January 29, 2024 |
| Accepted | March 12, 2024 |
| Published | March 27, 2024 |