Lactoferrin: An Overview

Year : 2021 | Volume : | Issue : 2 | Page : 20-

    Daddaladka Krishnayya Samartha

  1. Halugudde Nagaraja Sarjan

  1. Post-graduate Student, Department of Zoology, University of Mysore, Manasagangotri, Mysore, Karnataka, India
  2. Lecturer, Department of Zoology, University of Mysore, Manasagangotri, Mysore, Karnataka, India


Lactoferrin (Lf) is an iron-binding glycoprotein synthesized predominantly in mammary glands of animals. Lf is majorly found in milk and colostrum of livestock and mouse. The presence of Lf in indigenous breeds of cattle has a significant role in exerting immunoprotection. Studies have highlighted the significant activities of Lf viz., anti-parasitic, antioxidant, anti-cancer, anti- inflammatory, antimicrobial, and growth factor activator in cell cultures. The capacity of Lf to bind to different types of cells enhances its ability to prevent free radical-mediated damage or microbial invasion. However, further studies involving Lf-cell interactions will reveal its molecular insights towards antimicrobial, immune-modulatory, and anti-neoplastic properties.

Keywords: Anti-oxidant, bovine, cattle, colostrum, lactoferrin, milk

[This article belongs to Research & Reviews : Journal of Dairy Science & Technology(rrjodst)]

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Regular Issue Open Access Article
Volume 10
Issue 2
Received August 30, 2021
Accepted August 30, 2021
Published September 24, 2021