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Shilpi Islam,
- Professor, Department of Animal Science and Nutrition, Gazipur Agricultural University, Salna, Gazipur-1706, , Bangladesh
Abstract
Advances in gene editing technologies have transformed the landscape of livestock production by enabling precise manipulation of genetic material associated with productivity, health, and environmental adaptability. Tools such as CRISPR Cas9 and emerging next generation editors allow targeted modifications that improve feed efficiency, growth performance, nutrient utilization, and stress tolerance in farm animals. This review highlights the genetic basis of feed efficiency and metabolic regulation, focusing on key genes and pathways involved in digestion, energy balance, protein synthesis, and lipid metabolism. It further explores how gene editing can be applied to improve economically important traits such as feed conversion ratio, residual feed intake, body composition, and nutrient digestibility. Integration of genetic technologies with nutritional strategies, including precision feeding and nutrigenomics, enables optimized expression of desirable traits and improved production efficiency. Species specific applications in cattle, poultry, and swine demonstrate the versatility of gene editing in addressing diverse production challenges. In addition, gene-based improvements contribute significantly to climate resilience by enhancing heat tolerance, metabolic flexibility, and stress adaptation. Despite its potential, the application of gene editing in livestock faces challenges including off target effects, ethical concerns, regulatory variability, and risks to genetic diversity. Public perception and animal welfare considerations also play critical roles in shaping adoption pathways. Future directions emphasize integration of multi omics technologies and artificial intelligence to enhance predictive breeding and precision nutrition systems. Overall, gene editing, when responsibly applied, offers a powerful approach to developing sustainable, efficient, and climate resilient livestock production systems that support global food security under changing environmental conditions.
Keywords: Feed efficiency, gene editing, genomic interventions, livestock, metabolic adaptation, precision breeding, trait improvement
Shilpi Islam. Gene Edited Livestock for Enhanced Feed Efficiency and Metabolic Adaptation Through Precision Genomic Interventions. Research and Reviews : A Journal of Biotechnology. 2026; 16(02):-.
Shilpi Islam. Gene Edited Livestock for Enhanced Feed Efficiency and Metabolic Adaptation Through Precision Genomic Interventions. Research and Reviews : A Journal of Biotechnology. 2026; 16(02):-. Available from: https://journals.stmjournals.com/rrjobt/article=2026/view=246519
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Research and Reviews : A Journal of Biotechnology
| Volume | 16 |
| 02 | |
| Received | 01/05/2026 |
| Accepted | 24/05/2026 |
| Published | 05/06/2026 |
| Publication Time | 35 Days |
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