A Comprehensive Review on Coumarin Derivatives


Year : 2025 | Volume : 16 | 01 | Page : –
    By

    Sasikumar S,

  • Silambarasan S,

  • Vijaiyalakshmi R,

  • Anbazhagan S,

  1. Student, Department of Pharmacy, Surya College of Pharmacy, Villupuram Dt, Tamil Nadu, India
  2. Student, Department of Pharmacy, Surya College of Pharmacy, Villupuram Dt, Tamil Nadu, India
  3. Assitant Professor, Department of Pharmaceutical Sciences, Surya College of Pharmacy, Villupuram Dt, Tamil Nadu, India
  4. Principal, Department of Pharmaceutical Sciences, Surya College of Pharmacy, Villupuram Dt, Tamil Nadu, India

Abstract

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Coumarins are naturally occurring compounds found in plants, fungi, and microorganisms with diverse bioactivities. They have antithrombotic, anti-inflammatory, antioxidant, antimicrobial, antiviral, anticancer, and neuroprotective properties. Extracting coumarins, using methods like maceration and microwave- assisted extraction, is crucial for their applications. However, safety and toxicology are important, especially in pharmaceuticals, cosmetics, and food additives. Consuming moderate amounts of coumarin-rich foods is generally safe, but excessive intake raises concerns about hepatotoxicity and photosensitivity. Specific coumarin derivatives, like warfarin, require precise dosing and monitoring to prevent bleeding complications. The safety and toxicity profiles of coumarins depend on factors like compound type, dosage, and individual susceptibility.

Keywords: Coumarins, Synthesis, Extraction, Biological Applications, Coumarin around odorata

How to cite this article:
Sasikumar S, Silambarasan S, Vijaiyalakshmi R, Anbazhagan S. A Comprehensive Review on Coumarin Derivatives. Research and Reviews: A Journal of Pharmaceutical Science. 2025; 16(01):-.
How to cite this URL:
Sasikumar S, Silambarasan S, Vijaiyalakshmi R, Anbazhagan S. A Comprehensive Review on Coumarin Derivatives. Research and Reviews: A Journal of Pharmaceutical Science. 2025; 16(01):-. Available from: https://journals.stmjournals.com/rrjops/article=2025/view=0


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Ahead of Print Subscription Review Article
Volume 16
01
Received 13/01/2025
Accepted 05/02/2025
Published 25/02/2025
Publication Time 43 Days
112

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