Advancing Climate-Resilient Agriculture: Integrative Biotechnological Approaches for Sustainable Crop Production

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This is an unedited manuscript accepted for publication and provided as an Article in Press for early access at the author’s request. The article will undergo copyediting, typesetting, and galley proof review before final publication. Please be aware that errors may be identified during production that could affect the content. All legal disclaimers of the journal apply.

Year : 2026 | Volume : 16 | 02 | Page :
By

Anuj Yadav,

Rahul Sharma,

Shubhi Tripathi,

Shreya Gupta,

  1. Assistant professor, Department of Biotechnology, Bansal Institute of Engineering and Technology, Lucknow, U.P, 226201, Uttar Pradesh, India
  2. Student, Department of Biotechnology, Bansal Institute of Engineering and Technology, Lucknow, U.P, 226201, Uttar Pradesh, India
  3. Student, Department of Biotechnology, Bansal Institute of Engineering and Technology, Lucknow, U.P, 226201, Uttar Pradesh, India
  4. Student, Department of Biotechnology, Bansal Institute of Engineering and Technology, Lucknow, U.P, 226201, Uttar Pradesh, India

Abstract

Climate change presents a major challenge to global agriculture by increasing the occurrence and severity of both non-living and living stress factors, such as drought, high temperatures, salt buildup, waterlogging, and new pests and diseases. These stressors interfere with the normal functioning of plants at the physical, chemical, and genetic levels, which in turn results in lower crop yields and poorer quality. While traditional methods of plant breeding played a key role during the Green Revolution, they are typically slow and not enough to improve complex traits related to stress resistance, which are influenced by many genes. Modern plant biotechnology offers more accurate and effective ways to improve the ability of crops to withstand stress. Methods like genetic modification, genome editing (such as CRISPR-Cas9, TALENs, and ZFNs), and omics technologies (including genomics, transcriptomics, proteomics, and metabolomics), along with tissue culture techniques, help in creating crop varieties that can endure harsh conditions. The use of microbial biotechnology, such as beneficial bacteria in the root zone and mycorrhizal fungi, also supports better nutrient absorption, improved stress resistance, and more environmentally friendly farming. Examples like drought-resistant maize, salt-tolerant rice, and heat-resistant wheat show how these technologies can be applied effectively. Newer approaches like artificial intelligence, synthetic biology, high-speed plant trait analysis, and climate-aware agriculture are likely to speed up the creation of crops that can thrive under changing conditions. In summary, combining biotechnological advances with sustainable farming methods is crucial for ensuring global food supply and building agriculture that can withstand climate changes.

Keywords: Climate-resilient crops, Genetic engineering, Genome editing, Multi-omics, Microbial biotechnology, Abiotic stress tolerance, Sustainable agriculture, High-throughput phenotyping, Synthetic biology, Climate-smart agriculture

How to cite this article: Anuj Yadav, Rahul Sharma, Shubhi Tripathi, Shreya Gupta. Advancing Climate-Resilient Agriculture: Integrative Biotechnological Approaches for Sustainable Crop Production. Research and Reviews : A Journal of Biotechnology. 2026; 16(02):-.
How to cite this URL: Anuj Yadav, Rahul Sharma, Shubhi Tripathi, Shreya Gupta. Advancing Climate-Resilient Agriculture: Integrative Biotechnological Approaches for Sustainable Crop Production. Research and Reviews : A Journal of Biotechnology. 2026; 16(02):-. Available from: https://journals.stmjournals.com/rrjobt/article=2026/view=258363

References

1. Janni M, Maestri E, Gullì M, Marmiroli M, Marmiroli N. Plant responses to climate change, how global warming may impact on food security: a critical review. Frontiers in plant science. 2024 Jan 5;14:1297569.

2. Saleem A, Anwar S, Nawaz T, Fahad S, Saud S, Ur Rahman T, Khan MN, Nawaz T. Securing a sustainable future: the climate change threat to agriculture, food security, and sustainable development goals. Journal of Umm Al-Qura University for Applied Sciences. 2025 Sep;11(3):595-611.

3. Janni M, Maestri E, Gullì M, Marmiroli M, Marmiroli N. Plant responses to climate change, how global warming may impact on food security: a critical review. Frontiers in plant science. 2024 Jan 5;14:1297569.

4. Thingujam D, Gouli S, Cooray SP, Chandran KB, Givens SB, Gandhimeyyan RV, Tan Z, Wang Y, Patam K, Greer SA, Acharya R. Climate-resilient crops: integrating AI, multi-omics, and advanced phenotyping to address global agricultural and societal challenges. Plants. 2025 Aug 29;14(17):2699.

5. Krishna TP, Veeramuthu D, Maharajan T, Soosaimanickam M. The era of plant breeding: Conventional breeding to genomics-assisted breeding for crop improvement. Current genomics. 2023 Jan 1;24(1):24-35.

6. Sun L, Lai M, Ghouri F, Nawaz MA, Ali F, Baloch FS, Nadeem MA, Aasim M, Shahid MQ. Modern plant breeding techniques in crop improvement and genetic diversity: From molecular markers and gene editing to artificial intelligence—A critical review. Plants. 2024 Sep 24;13(19):2676.

7. Ansori AN, Antonius Y, Susilo RJ, Hayaza S, Kharisma VD, Parikesit AA, Zainul R, Jakhmola V, Saklani T, Rebezov M, Ullah ME. Application of CRISPR-Cas9 genome editing technology in various fields: A review. Narra J. 2023 Aug 27;3(2):e184.

8. Chen F, Chen L, Yan Z, Xu J, Feng L, He N, Guo M, Zhao J, Chen Z, Chen H, Yao G. Recent advances of CRISPR-based genome editing for enhancing staple crops. Frontiers in plant science. 2024 Sep 23;15:1478398.

9 Jain A, Sarsaiya S, Singh R, Gong Q, Wu Q, Shi J. Omics approaches in understanding the benefits of plant-microbe interactions. Frontiers in Microbiology. 2024 May 27;15:1391059.

10. Kazemi Oskuei B, Masi A, Kosmala A, Mahna N. Plant stress and proteomics in medicinal plants. Frontiers in Plant Science. 2025 Sep 30;16:1656247.

11. Wijerathna-Yapa A, Hiti-Bandaralage J. Tissue culture—a sustainable approach to explore plant stresses. Life. 2023 Mar 14;13(3):780.

12. Arabzai MG, Huang D, Mohammadi NK, Gao J, Wang X, Zheng P, Qin Y, Wang L. Techniques and advantages of microspore culture for crop improvement. Plant Growth Regulation. 2025 Aug;105(4):903-18.

13. Guru GR, Ramteke PW, Veres C, Vágvölgyi C. Recent advances in the use of plant growth promoting microorganisms for enhancing micropropagation efficiency. Frontiers in Plant Science. 2026 Jan 27;16:1699873.

14. Abdul Aziz M, Brini F, Rouached H, Masmoudi K. Genetically engineered crops for sustainably enhanced food production systems. Frontiers in plant science. 2022 Nov 8;13:1027828.

15. Kim KH, Park D, Lee BM. Biotechnological strategies to enhance maize resilience under climate change. Biology. 2026 Jan 16;15(2):161.

16. Wagh SG, Patil AM, Patil GB, Bhor SA, Pawar KR, Shinde H. Programmable plant immunity: synthetic biology for climate-resilient agriculture. SynBio. 2026 Jan 4;4(1):1.


Ahead of Print Subscription Review Article
Volume 16
02
Received 10/09/2026
Accepted 15/09/2026
Published 25/09/2026
Publication Time 15 Days


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