4D Printing in Drug Delivery: Application of Shape- Morphing Materials in Controlled Drug Release

Year : 2025 | Volume : 12 | Issue : 03 | Page : 08 16
    By

    Kulpesh Kumar Dubey,

  • Akanksha Dwivedi,

  • G.N. Darwhekar,

  1. Student, Department of Pharmaceutics, Acropolis Institute of Pharmaceutical Education and Research, Indore, Madhya Pradesh, India
  2. Associate Professor, Department of Pharmaceutics, Acropolis Institute of Pharmaceutical Education and Research, Indore, Madhya Pradesh, India
  3. Principal, Department of Pharmacy, Acropolis Institute of Pharmaceutical Education and Research, Indore, Madhya Pradesh, India

Abstract

Four-dimensional printing technology has transformed the pharmaceutical landscape, offering unprecedented opportunities for innovation in drug development and delivery. This emerging technology enables the creation of complex geometries and customized structures, facilitating the design of personalized medications tailored to individual patient needs. Personalized dosing and drug release profiles, customized pill shapes and sizes for improved swallowability. Enhanced drug solubility and bioavailability, rapid prototyping and testing of pharmaceutical products. Development of complex drug delivery systems such as implants and microneedles. Improved patient compliance through customized medication regimens, reduced production costs, and increased efficiency. Enhanced drug stability and self-life, potential for localized and targeted drug delivery. This study explores the current state of four-dimensional printing in pharmaceuticals, highlighting its benefits, challenges, and future directions. The integration of four-dimensional printing technology has the potential to revolutionize the pharmaceutical industry, transforming the way drugs are designed, manufactured, and delivered. Development of four-dimensional printing polymeric materials and technology.

Keywords: 4D printing, pharmaceuticals, personalized medicine, drug development, drug delivery, smart materials, shape memory polymer

[This article belongs to Trends in Drug Delivery ]

How to cite this article:
Kulpesh Kumar Dubey, Akanksha Dwivedi, G.N. Darwhekar. 4D Printing in Drug Delivery: Application of Shape- Morphing Materials in Controlled Drug Release. Trends in Drug Delivery. 2025; 12(03):08-16.
How to cite this URL:
Kulpesh Kumar Dubey, Akanksha Dwivedi, G.N. Darwhekar. 4D Printing in Drug Delivery: Application of Shape- Morphing Materials in Controlled Drug Release. Trends in Drug Delivery. 2025; 12(03):08-16. Available from: https://journals.stmjournals.com/tdd/article=2025/view=236151


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Regular Issue Subscription Review Article
Volume 12
Issue 03
Received 18/06/2025
Accepted 07/07/2025
Published 01/08/2025
Publication Time 44 Days
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