Controlled Release Drug Delivery Using 3D Printing Techniques: A Current Scenario In Personalized Medicine

Year : 2025 | Volume : 12 | Issue : 03 | Page : 28 43
    By

    Sudhamani T,

  • Mani Priya P,

  • Dhanasekar J,

  • Selvakumar M,

  • Nandhakumaran S,

  • Lathamani L,

  • Thirumurthy R,

  1. Professor &Head, Department of Pharmaceutics, Chemistry, Vivekanandha Pharmacy College for Women, Sankari, Tamil Nadu, India
  2. Student, Department of Pharmaceutics, Vivekanandha Pharmacy College for Women, Sankari, Tamil Nadu, India
  3. Associate Professor, Department of Pharmaceutics, Vivekanandha Pharmacy College for Women, Sankari, Tamil Nadu, India
  4. Associate Professor, Department of Pharmaceutics, Vivekanandha Pharmacy College for Women, Sankari, Tamil Nadu, India
  5. Associate Professor, Department of Pharmaceutics, Vivekanandha Pharmacy College for Women, Sankari, Tamil Nadu, India
  6. Associate Professor, Department of Pharmaceutics, Vivekanandha Pharmacy College for Women, Sankari, Tamil Nadu, India
  7. Professor & Head, Department of Pharmaceutical Chemistry, Vivekanandha Pharmacy College for Women, Sankari, Tamil Nadu, India

Abstract

Three-dimensional (3D) printing is particularly influencing the pharmaceutical manufacturing sector in the creation of controlled release drug delivery systems. This technology enables the precise fabrication of personalized medicines with tailored drug release profiles, dosages, and geometries, marking a significant advancement over traditional mass production methods. An array of 3D printing techniques, including extrusion-based, powder-based, and others, can be used to build complex dosage forms that regulate drug release through processes like dissolution, diffusion, osmosis, and erosion. By adjusting the composition and size of these shells, drug release rates can be finely tuned, supporting the goals of personalized medicine and improved patient compliance. While 3D printing offers significant advantages-including on-demand manufacturing, dose personalization, and the ability to create multidrug or multi-compartment dosage forms—it also faces challenges related to material selection, production capacity, regulatory standards, and quality control. On-going advancements in materials science, process optimization, and regulatory frameworks are expected to further expand the clinical applications and market growth of 3D printed controlled release pharmaceuticals in the coming years. This current review describes briefly the materials and methods, design strategy and applications of 3D printing technique for controlled release drug delivery.

Keywords: 3D printing techniques, Personalized Medicine, extrusion-based printing, drug delivery, liquid – based and Powder-based system.

[This article belongs to Trends in Drug Delivery ]

How to cite this article:
Sudhamani T, Mani Priya P, Dhanasekar J, Selvakumar M, Nandhakumaran S, Lathamani L, Thirumurthy R. Controlled Release Drug Delivery Using 3D Printing Techniques: A Current Scenario In Personalized Medicine. Trends in Drug Delivery. 2025; 12(03):28-43.
How to cite this URL:
Sudhamani T, Mani Priya P, Dhanasekar J, Selvakumar M, Nandhakumaran S, Lathamani L, Thirumurthy R. Controlled Release Drug Delivery Using 3D Printing Techniques: A Current Scenario In Personalized Medicine. Trends in Drug Delivery. 2025; 12(03):28-43. Available from: https://journals.stmjournals.com/tdd/article=2025/view=224793


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Regular Issue Subscription Review Article
Volume 12
Issue 03
Received 02/08/2025
Accepted 13/08/2025
Published 23/08/2025
Publication Time 21 Days
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