A Review on Phytochemical and Pharmacological Properties of Anacyclus Pyrethrum (Akarkara)

Year : 2025 | Volume : 12 | Issue : 01 | Page : 102 110
    By

    Himanshu Rajendra Nikam,

  • Yogesh B. Rokade,

  • Umakant S.Jugtap,

  • Sagar Chavhan,

  • Rohit S. Marathe,

  • Athav Kamble,

  1. Student, Department of Pharmaceuties, P. S. G. V. P. Mandal’s College of Pharmacy, shahada, Maharashtra, India
  2. Student, Department of Pharmaceuties, P. S. G. V. P. Mandal’s College of Pharmacy, shahada, Maharashtra, India
  3. Student, Department of Pharmaceuties, P. S. G. V. P. Mandal’s College of Pharmacy, shahada, Maharashtra, India
  4. Student, Department of Pharmaceuties, P. S. G. V. P. Mandal’s College of Pharmacy, shahada, Maharashtra, India
  5. Student, Department of Pharmaceuties, P. S. G. V. P. Mandal’s College of Pharmacy, shahada, Maharashtra, India
  6. Student, Department of Pharmaceuties, P. S. G. V. P. Mandal’s College of Pharmacy, shahada, Maharashtra, India

Abstract

The wild species Anacyclus pyrethrum, or A. pyrethrum, is a member of the Asteraceae family. It is commonly known as Akarkara. It originated in Spain, Morocco, and Algeria, and has since spread to Sri Lanka, India, Ukraine, Germany, Myanmar, France, and Poland. It is the benefits of bioactive compounds of plant found the chemical makeup, analgesic, anti-inflammatory, and wound-healing effects of hydroalcoholic extracts of A. pyrethrum’s roots, seeds, leaves, and capitula. It is mainly used in Traditional Ayurvedic Medicine. The number of chemical compounds has been reported from A. Pyrethrum including steroids, tri-terpenoids, reducing sugar, phenol, alcohol, flavonoids, saponin, tannin, anthroquinone amino acids and catechins. This collection will assist in developing new active principles and nutraceuticals for treating drug resistance and chronic disease vectors. The plant has a variety of uses, including sex stimulation, antidiabetic, antioxidant, and treatment of various ailments, such as asthama, cardiac diseases, and throat problems. It can also alleviate laziness, nerve weakness, stomach problems, arthritis, sciatica, diuretic, tooth and gum problems, aphrodisiacs, hiccoughs, epilepsy, headaches, pains, muscle relaxants, worm infestation, anti-rheumatism, anticonvulsant, brain tonic, common cold, and other human-related disorders. This work will be useful for future bioactivity and phytochemical studies on this plant species.

Keywords: Anacyclus Pyrethrum, chemical makeup, analgesic, anti-inflammatory, anti microbial activity.

[This article belongs to Research & Reviews: A Journal of Pharmacognosy ]

How to cite this article:
Himanshu Rajendra Nikam, Yogesh B. Rokade, Umakant S.Jugtap, Sagar Chavhan, Rohit S. Marathe, Athav Kamble. A Review on Phytochemical and Pharmacological Properties of Anacyclus Pyrethrum (Akarkara). Research & Reviews: A Journal of Pharmacognosy. 2025; 12(01):102-110.
How to cite this URL:
Himanshu Rajendra Nikam, Yogesh B. Rokade, Umakant S.Jugtap, Sagar Chavhan, Rohit S. Marathe, Athav Kamble. A Review on Phytochemical and Pharmacological Properties of Anacyclus Pyrethrum (Akarkara). Research & Reviews: A Journal of Pharmacognosy. 2025; 12(01):102-110. Available from: https://journals.stmjournals.com/rrjopc/article=2025/view=208597


References

  1. Holiman A. Plants in Medicine. Chelsea Physic Garden. The Chelsea Physic Garden Co Ltd; 1989.
  2. Palthur MP, Palthur SS, Chitta SK. Nutraceuticals: Concept and regulatory scenario. Int J Pharm Pharm Sci. 2010;2(2):14–20.
  3. Duraipandiyan V, Ayyanar M, Ignacimuthu S. Antimicrobial activity of some ethnomedicinal plants used by Paliyar tribe from Tamil Nadu, India. BMC Complement Altern Med. 2006;6:35. doi:10.1186/1472-6882-6–35
  4. Abraham Z. Glimpses of Indian Ethnobotany. Oxford & IBH Publishing Co.; 1981. p. 315.
  5. Kishor K, Lalitha KG. Pharmacognostical studies on the root of Anacyclus pyrethrum DC. Indian J Nat Prod Resour. 2012;3(4):518–26.
  6. Puri HS. Rasayana: Ayurvedic Herbs for Longevity & Rejuvenation. Taylor & Francis; 2003. p. 71–3.
  7. Kumar VK, Lalitha KG. Pharmacognostical studies on the root of Anacyclus pyrethrum DC. Indian J Nat Prod Resour. 2012;3:518–26.
  8. Kushwaha MN, Jatav VS, Pandey S. Plant Anacyclus pyrethrum – A review. Res J Pharmacogn Phytochem. 2012;4(3):164–70.
  9. Tyagi S, Ashim MM, Narendra KS, Manoj KS, Bhardwaj P, Singh RK. Antidiabetic effect of Anacyclus pyrethrum DC in alloxan induced diabetic rats. Eur J Biol Sci. 2011;3(4):117–20.
  10. El Oualidi J, Khamar H, Fennane M, Ibn Tattou M, Chauvet S, Taleb MS. Checklist des endémiques et spécimens types de la flore vasculaire de l’Afrique du Nord. Doc Inst Sci. 2012;25:1–89.
  11. Sharma V, Thakur M, Chauhan NS, Dixit VK. Effects of petroleum extract of Anacyclus pyrethrum DC on sexual behavior in male rats. J Chin Integr Med. 2010;8(8):767–73. doi:10.3736/jcim20100807
  12. Greger H. Comparative phytochemistry and systematics of Anacyclus. Biochem Syst Ecol. 1978;6(1):11–7. doi:10.1016/0305-1978(78)90019-4
  13. Batanouny K. Guide to Medicinal Plants in North Africa. IUCN; 2005:35–7.
  14. Kumar V, Choudhary AK. Akarkara: A Versatile Medicinal Plant – A Review. J Ayurveda Holist Med. 2016;4:1–14.
  15. Ministry of Agriculture and Rural Development of Kenya. Kenya’s Pyrethrum Industry; 2005. pp. 1–10.
  16. Rankou H, Ouhammou A, Taleb M, Manzanilla V, Martin G. Anacyclus pyrethrum. The IUCN Red List of Threatened Species 2017: e.T202924A209509689. https://dx.doi.org/10.2305/IUCN.UK.2017-3.RLTS.T202924A209509689.en. Accessed 2025 Mar 24.
  17. Elazzouzi H, Soro A, Elhilali F, Bentayeb A, El Belghiti MA, Zair T. Phytochemical study of Anacyclus pyrethrum and in vitro antibacterial activity. Adv Nat Appl Sci. 2014;8(8):131–41.
  18. Selles C. Valorisation d’une plante médicinale à activité antidiabétique: Anacyclus pyrethrum. Université Abou Bekr Belkaid, Tlemcen; 2012 Jun 30:30.
  19. Canli K, Yetgin A, Akata I, Altuner EM. Antimicrobial activity and chemical composition screening of Anacyclus pyrethrum root. Indian J Pharm Educ Res. 2017;51(3) Suppl:S244–8.
  20. Koperuncholan M, John SA. Antimicrobial and phytochemical screening in Myristica dactyloides. J Pharm Res. 2011;4(2):398–400.
  21. John SA, Koperuncholan M. Antibacterial activities of various solvent extracts from Impatiens balsamina. Int J Pharm Bio Sci. 2012;3(2):401–6.
  22. Boonen J, Sharma V, Dixit VK, Burvenich C, De Spiegeleer B. LC-MS N-alkylamide profiling of an ethanolic Anacyclus pyrethrum root extract. Planta Med. 2012;78(16):1787–95.
  23. Bourkhiss M, Hnach M, Lakhlifi T, Boughdad A, Farah A, Satrani B. Composition of essential oils of Thuya de Berbere. Technol Lab. 2011;6:64–8.
  24. Subasri G, John AS. Phytochemical compounds, trace metals and antimicrobial activity of Anacyclus pyrethrum. Int J Adv Sci Res. 2016;2(1):32–7.
  25. Mokhtari KE, Kouali ME, Talbi M, Hajji L, Brouzi AE. Insecticidal activity of Anacyclus pyrethrum essential oil. Mediterr J Chem. 2020;10(1).
  26. Francois-Xavier G. Le materiel vegetal et les huiles essentielles. Corporation LASEVE-UQAC, Chicoutimi (Quebec); 2001.
  27. Ghanmi M, Satrani B, Aafi A, et al. Harvest time effects on essential oils of Artemisia herba-alba. Phytotherapie. 2010;8(5):295–301.
  28. Pandey S, Shukla A, Pandey S, Pandey A. Overview of herb Sanjeevani (Selaginella bryopteris). Pharma Innov. 2017;6:11–4.
  29. Vignesh G, Arunachalam S, Vignesh S, Arthur James R. BSA binding and antimicrobial studies of PEI–copper complexes. Spectrochim Acta A Mol Biomol Spectrosc. 2012;96:108–16.
  30. Pahuja M, Mehla J, Reeta KH, Joshi S, Gupta YK. Anacyclus pyrethrum root extract ameliorates seizures and oxidative stress. Epilepsy Res. 2012;98(2–3):157–65.
  31. Usmani A, Khushtar M, Arif M, et al. Pharmacognostic and phytopharmacology study of Anacyclus pyrethrum. J Appl Pharm Sci. 2016;6:144–50.
  32. Bouhafsoun A, Yilmaz MA, Boukeloua A, et al. Quantification of phenolics in Chamaerops humilis L. Food Sci Technol. 2018;38(Suppl 1):242–7. doi:10.1590/fst.19917
  33. Verpoorte R. La pharmacognosie du nouveau millénaire. In: Fleurentin J, Mazars G, Pelt JM, editors. Des Sources du Savoir aux Médicaments du Futur. Marseille: IRD Éditions; 2014. p. 263–74.
  34. Ekor M. Herbal medicine use: adverse reactions and safety monitoring. Front Pharmacol. 2014;4:177.
  35. Annalakshmi R, Uma RG, Chandran S, Muneeswaran A. Anacyclus pyrethrum: A review. Indian J Drugs Dis. 2012;3:9.
  36. Gui RK, Mamyrbékova-Békro JA, Pirat JL, et al. Identification de composés phénoliques extraits. J Soc Ouest-Afr Chim. 2014;8:57–63.
  37. Amresh G, Reddy G, Rao C, Singh P. Anti-inflammatory activity of Cissampelos pareira root. J Ethnopharmacol. 2007;110:526–31.
  38. Liu HL, Jiang WB, Xie MX. Flavonoids: Recent advances as anticancer drugs. Recent Pat Anticancer Drug Discov. 2010;5:152–64.
  39. Tsai HY, Lin YT, Tsai CH, Chen YF. Paeoniflorin and nociceptive behaviour. J Ethnopharmacol. 2001;75:267–71. doi:10.1016/S0378-8741(00)00403-7
  40. Gupta M, Mazumder UK, Kumar RS, et al. Methanol extract from Bauhinia racemosa stem bark. J Ethnopharmacol. 2005;98:267–73. doi:10.1016/j.jep.2005.01.018
  41. Sujith K, Darwin CR, Suba V. Antioxidant activity of ethanolic root extract of Anacyclus pyrethrum. Int Res J Pharm. 2011;2:222–6.

Regular Issue Subscription Review Article
Volume 12
Issue 01
Received 24/02/2025
Accepted 24/03/2025
Published 23/04/2025
Publication Time 58 Days


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