Hydro-alcoholic Extract of Herbal Formulation and Evaluation of Papaya leaf And Orange Peel for treatment of Dengue Fever

Year : 2025 | Volume : | : | Page : –
By
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Puja Kumari,

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Nirmal Dongre,

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Raghvendra Dubey,

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Paridhi Dubey,

  1. Assistant Professor, Department of Pharmaceutics, Institute of Pharmaceutical Sciences, Sage University Indore, Madhya Pradesh, India
  2. Head of Department, Department of Pharmacognosy, Institute of Pharmaceutical Sciences, Sage University Indore, Madhya Pradesh, India
  3. Head of institute, Department of Pharmacognosy, Institute of Pharmaceutical Sciences, Sage University Indore, Madhya Pradesh, India
  4. Student, Department of Pharmaceutics, Institute of Pharmaceutical Sciences, Sage University Indore, Madhya Pradesh, India

Abstract

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The fastest-spreading viral disease in the world is dengue contamination, which is spread by mosquitoes. Carica papaya leaf juice aids in raising the platelet count, and it occurs primarily in tropical and subtropical countries. The primary goal of this study is to inform medical experts about the use of Carica papaya leaf extract formulations (SYRUP) to treat dengue fever, a potentially fatal illness. Approach: To cure this illness, a water extract was prepared using a certain amount of Carica papaya leaf. The numerous pharmacological characteristics of the chemical components found in Carica papaya leaf extract were shown to be stable after treating the elevated dengue fever. This indicates that Carica papaya leaf extracts are a herbal method of treating dengue fever.We came to the conclusion that caricapa payalea extract can be used to treat dengue fever, which can raise the platelets in patients with the illness. It is also one of the simplest and least expensive ways to cure dengue fever, and it helps treat the illness without causing any negative side effects.

Keywords: Carica papaya, extract, dengue, platelets count, novel formulation.

How to cite this article:
Puja Kumari, Nirmal Dongre, Raghvendra Dubey, Paridhi Dubey. Hydro-alcoholic Extract of Herbal Formulation and Evaluation of Papaya leaf And Orange Peel for treatment of Dengue Fever. Research & Reviews: A Journal of Pharmaceutical Science. 2025; ():-.
How to cite this URL:
Puja Kumari, Nirmal Dongre, Raghvendra Dubey, Paridhi Dubey. Hydro-alcoholic Extract of Herbal Formulation and Evaluation of Papaya leaf And Orange Peel for treatment of Dengue Fever. Research & Reviews: A Journal of Pharmaceutical Science. 2025; ():-. Available from: https://journals.stmjournals.com/rrjops/article=2025/view=0

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References

  1. Yunita F, Hanani E, Kristianto J.The effect of Carica papaya L. leaves extract capsules on platelets count and hematocrit level in dengue fever patient. Int J Med Arom at Plants. 2012; 2(4):573-8.
  2. Kala CP.Leaf juice of Carica papaya L.Are medy of dengue fever.Med Aromat Plants. 2012;1-6:
  3. Vuong QV, Hirun S, Roach PD,Bowyer MC,Phillips PA,Scarlett CJ. Effect of extraction Conditions on total phenolic compounds and antioxidant activities of Carica papaya leaf aqueous extracts. Journal of Herbal  Medicine. 2013 Sep 1;3(3):104-11.
  1. Sanjeev Kumar B,Naik S,Jayantee K, Misra U.Acute disseminated encephalomyelit is following dengue virus infection. J Neuro infect Dis. 2014;5(139):2. 5)
  2. Sheikh NA, Younas NE, Akhtar TA. Effect of Carica papaya leaf formulation on hematology and serology of normal rat. Biologia (Pakistan). 2014;60(1):139-42.
  3. Kumar PV. Dengue and draw back so fmarketed Carica papaya leaves supplements. International Journal of Green Pharmacy (IJGP). 2016 Mar 21;10(1).
  4. Ayoola PB, Adeyeye A. Phytochemical and nutrient evaluation of Carica papaya (pawpaw) leaves. Ijrras. 2010 Dec; 5 (3):325-8.
  5. AnjumV, Ansari SH, Naquvi KJ, Arora P, Ahmad A. Development of quality standards of Carica papaya leaves. Sch Res Lib. 2013; 5(2):370-6.
  6. Chandrasekaran R, Gnanasekar S, Seetharaman P, Keppanan R,Arockiaswamy W, Sivaperumal S. FormulationofCaricapapayalatex-functionalizedsilvernanoparticlesforitsimprovedantibacterial and anticancer applications. Journal of Molecular Liquids. 2016 Jul 1; 219: 232-8. https://doi.org/10.1016/j.molliq.2016.03.038
  7. OtsukiN, DangNH, KumagaiE, Kondo A, IwataS, MorimotoC.Aqueous extract of Carica papaya leaves exhibits anti-tumor activity and immunomodulatory effects. Journal of ethnopharmacology. 2010 Feb 17;127(3):760-7 https://doi.org/10.1016/j.jep.2009.11.024
  8. Emeruwa AC. Antibacterial substance from Carica papaya fruit extract. Journal of natural products. 1982 Mar; 45(2):123-7.
  9. `Ahmad N, Fazal H, Ayaz M, Abbasi BH, Mohammad I, Fazal Dengue fever treatment with Carica papaya leaves extracts.   Asian Pacific journal of tropical biomedicine.2011Aug1;1(4) 330-333  https://doi.org/10.1016/S2221-1691(11)60055-5
  1. Dharmarathna SL, Wickramasinghe S, Waduge RN, Rajapakse RP, Kularatne SA. Does Carica papaya leaf-extract increase the platelet count? An experimental study in a murine model. Asian Pacific Journal of Tropical Biomedicine. 2013 Sep 1;3(9):720-4. https://doi.org/10.1016/S2221-1691(13)60145-8
  2. Halim SZ, Abdullah NR, AfzanA, Rashid BA,Jantan I, Ismail Z.Acute toxicity study of Carica papaya leaf extract in Sprague Dawley rats. Journal of Medicinal Plants Research. 2011 May 18;5(10):1867-72.
Ahead of Print Subscription Review Article
Volume
Received 11/11/2024
Accepted 09/01/2025
Published 15/01/2025
255