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Special Issue
Topic

Liposome-based methods are used to create polymersomes

Guest Editor:

        • Abstract Submission Deadline : 30/11/2023

        Manuscript Submission Deadline : 25/12/2023

        [This article belongs to Special Issue Liposome-based methods are used to create polymersomes under section ijpse, ijpse in (ijpse, ijpse)]

        Special Issue Description

        Hollow shell nanoparticles (NPs) called polymersomes can be used to distribute medications. It has been demonstrated that biodegradable polymersomes may load, distribute, and absorb drug combinations in the cytosol by taking advantage of the block copolymer vesicles’ thick membrane, aqueous lumen, and pH-triggered release within endolysosomes. Polymersomes that are biodegradable and particular for a given target deliver their medications into tumor cell endosomes when they degrade in an acidic environment. A polymersome is made of two layers of synthetic polymers, which are much larger than individual phospholipids but share many of the same chemical properties. This is in contrast to cell membranes and liposomes, which are made of a double layer of phospholipids. The methods used to create liposomes are also employed to create polymersomes. The most popular technique is thin-film hydration, which involves first suspending diblock copolymers in a volatile organic solvent and drying them onto a glass or Teflon surface. The dried thin film is then hydrated in an aqueous solution that contains the chemical moieties that will be contained within the polymersomes, sonicated, and extruded to the required size. Since lengthy circulation periods and improved tumor accumulation are important for imaging applications, most polymersomes are shrunk to less than 150 nm in diameter. However, due to the high membrane durability, polymersomes with a diameter of tens of microns can also be created.

        Editor Keywords

        Thin film, Copolymers, Microfluidic, Liposomes, Synthetic Polymers, Phospholipids, Tumor Regression

        Manuscript Submission information

        Manuscripts should be submitted online by registering and logging in to this link. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed.
        Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent on email address:[email protected] for announcement on this website.

        Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page.

        Participating journals:

        Journal Name

        International Journal of Polymer Science & Engineering, International Journal of Polymer Science & Engineering

        Abbrivation

        ijpse, ijpse

        ISSN

        2455-8745, 2455-8745

        Since

        2015

        APC

        950  $