Clinical Trial to Find the (Asbab) Aetiology and (Ilaj) Treatment of (Marz-e-Akyās Khusyat-ur-Rahim) Polycystic Ovarian Syndrome (PCOS)

Year : 2025 | Volume : 12 | Issue : 03 | Page : 30 37
    By

    Ruqaya Qayoom,

  • Mohammed Sheeraz Mushtaque Ahmed,

  • Shameem Ahmed Rather,

  • Naquibul Islam,

  1. Assistant Professor, Department of Moalajat, Regional Research Institute of Unani Medicine, University of Kashmir, Srinagar, Jammu & Kashmir, India
  2. Associate Professor, Department of Moalajat, Regional Research Institute of Unani Medicine, University of Kashmir, Srinagar, Jammu & Kashmir, India
  3. Professor, Department of Moalajat, Regional Research Institute of Unani Medicine, University of Kashmir, Srinagar, Jammu & Kashmir, India
  4. MD Coordinator, Regional Research Institute of Unani Medicine, University of Kashmir, Srinagar, Jammu & Kashmir, India

Abstract

Introduction: Polycystic Ovarian Syndrome (PCOS) is common endocrine disorder. It is clinically defined as the syndrome characterized by amenorrhoea, hirsutism and obesity associated with polycystic ovaries. Diagnosis is made on the Rotterdam criteria, established in 2003. The criteria require the presence of 2 of the following 3 criteria: 1. Oligo-ovulation or an ovulation. 2. Hyperandrogenism. 3. Polycystic ovaries through ultrasound evaluation. Methods: Diagnosed patients were enrolled in the trial into two groups: Test group (A) and Control group (B) after obtaining voluntary informed consent. The study was conducted at RRIUM, Naseem Bagh Campus, University of Kashmir from Dec 2018 to Aug 2019 after ethical approval. Total 89 patients were screened, 77 enrolled for the trial, 66 patients completed the study, 10 were drop out due to their personal reasons, 1 had adverse effect of menorrhagia after taking test medicine. The medicine is immediately stopped and patient recovers. The adverse effect of drug was sent to Pharmacovigilance unit. 66 diagnosed patients of PCOS were randomly divided into test group and control group, 33 patients in each group. Test drug (Safoof Kalawnji 2.25 g b.d with water) were given to group A and control drug Tab Metformin 500 mg b.d were given to group B for 2 months. Clinical assessment, biochemical tests and USG–pelvis were done for pre- and post-analysis. Result: The observations were clinically and statistically significant in both the groups. There are many aetiologies of PCOS, mentioned in our classical literature, one of the causes is ghalba bhalghm. There are many ways of alternative treatment, like Ilaj bil ghiza (Dietotherapy), Ilaj bil dawa (pharmacotherapy), Ilaj bit-Tadbeer (Regimenal Therapy). Conclusion: In this research, the pharmacotherapy was tested. The medicine used in this trial was powder of single herbal medicine, Nigella sativa Linn. This cause and effect of this clinical trial can be explained by Ilaj bil Zid and Mudirr properties of Showneez (Nigilla Sativa Linn), mentioned by Zakariya Razi.

Keywords: PCOS, Rotterdam, amenorrhoea, hirsutism, obesity

[This article belongs to Research & Reviews : A Journal of Unani, Siddha and Homeopathy ]

How to cite this article:
Ruqaya Qayoom, Mohammed Sheeraz Mushtaque Ahmed, Shameem Ahmed Rather, Naquibul Islam. Clinical Trial to Find the (Asbab) Aetiology and (Ilaj) Treatment of (Marz-e-Akyās Khusyat-ur-Rahim) Polycystic Ovarian Syndrome (PCOS). Research & Reviews : A Journal of Unani, Siddha and Homeopathy. 2025; 12(03):30-37.
How to cite this URL:
Ruqaya Qayoom, Mohammed Sheeraz Mushtaque Ahmed, Shameem Ahmed Rather, Naquibul Islam. Clinical Trial to Find the (Asbab) Aetiology and (Ilaj) Treatment of (Marz-e-Akyās Khusyat-ur-Rahim) Polycystic Ovarian Syndrome (PCOS). Research & Reviews : A Journal of Unani, Siddha and Homeopathy. 2025; 12(03):30-37. Available from: https://journals.stmjournals.com/rrjoush/article=2025/view=230962


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Regular Issue Subscription Original Research
Volume 12
Issue 03
Received 07/05/2025
Accepted 21/08/2025
Published 22/08/2025
Publication Time 107 Days
150

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