Vyanga, Present-Day Challenge: Insights from Toxicological Standpoint

Year : 2024 | Volume : 14 | Issue : 01 | Page : 11 16
    By

    Gyanendra Kumar Gupta,

  • Gagan Devi,

Abstract

The condition of Vyanga can have significant repercussions, as facial disfigurement not only impacts an individual’s psychological and social well- being but also hampers their overall contribution to society. This can result in reduced productivity, impaired social functioning, and diminished self-esteem. In classical Ayurvedic texts, Vyanga is categorized under Kshudrarogas, representing minor disorders with straightforward causes and symptoms. However, in certain instances, these conditions can lead to noticeable cosmetic impairments, causing considerable psychological distress. Vyanga presents as a distressing affliction that undermines an individual’s potential, necessitating definitive treatment as a recognized disease. Addressing Vyanga is crucial to alleviate the associated psychological burden and enable affected individuals to lead fulfilling lives with restored confidence and social integration. Consequently, effective interventions aimed at managing Vyanga not only enhance the individual’s quality of life but also contribute to the well-being of society as a whole. Therefore, prioritizing the recognition and treatment of Vyanga as a medically significant condition is imperative to address its multifaceted impacts comprehensively.

Keywords: :Vyanga, Kshudrarogas, Cosmetic, Facial lesions and Psychological.

[This article belongs to Research and Reviews: A Journal of Toxicology ]

How to cite this article:
Gyanendra Kumar Gupta, Gagan Devi. Vyanga, Present-Day Challenge: Insights from Toxicological Standpoint. Research and Reviews: A Journal of Toxicology. 2024; 14(01):11-16.
How to cite this URL:
Gyanendra Kumar Gupta, Gagan Devi. Vyanga, Present-Day Challenge: Insights from Toxicological Standpoint. Research and Reviews: A Journal of Toxicology. 2024; 14(01):11-16. Available from: https://journals.stmjournals.com/rrjot/article=2024/view=137113


References

1. Kauser S, Schallreuter KU, Thody AJ, Gummer C, Tobin DJ. Regulation of human epidermal melanocyte biology by beta-endorphin. J Invest Dermatol. 2003;120:1073–1080. doi: 10.1046/j.1523-1747.2003.12242.x. PubMed: 12787137.

2. Samhita S, Sharangdharacharya P. By Bramhananda Tripathi, Chaukhambha Surbharti Prakashan. Varanasi, India; 2013.

3. Duval C, Chagnoleau C, Pouradier F, Sextius P, Condom E, Bernerd F. Human skin model containing melanocytes: Essential role of keratinocyte growth factor for constitutive pigmentation-functional response to α-melanocyte stimulating hormone and forskolin. Tissue Eng Part C Methods. 2012;18:947–957. doi: 10.1089/ten.TEC.2011.0676. PubMed: 22646688.

4. Bramhananda Tripathi. Sarangdhara Samhita, Pandit Sharangdharacharya. Varanasi, India: Chaukhambha Surbharti Prakashan; 2013.

5. Tang S, Yang L, Kuroda Y, Lai S, Xie S, Zhang H, Katayama I. Herb Sanqi-Derived Compound K Alleviates Oxidative Stress in Cultured Human Melanocytes and Improves Oxidative-Stress-Related Leukoderma in Guinea Pigs. Cells. 2021;10:2057. doi: 10.3390/cells10082057. PubMed: 34440826.

6. Belote RL, Simon SM. Ca2+ transients in melanocyte dendrites and dendritic spine-like structures evoked by cell-to-cell signaling. J Cell Biol. 2020;219:e201902014. doi: 10.1083/jcb.201902014. PubMed: 31821412.

7. Brohem CA, Cardeal LBS, Tiago M, Soengas MS, Barros SBM, Maria-Engler SS. Artificial skin in perspective: Concepts and applications. Pigment Cell Melanoma Res. 2011;24:35–50. doi: 10.1111/j.1755-148X.2010.00786.x. PubMed: 21029393.

8. Qiu W, Yang K, Lei M, Yan H, Tang H, Bai X, Yang G, Lian X, Wu J. SCF/c-kit signaling is required in 12-O-tetradecanoylphorbol-13-acetate-induced migration and differentiation of hair follicle melanocytes for epidermal pigmentation. Cell Tissue Res. 2015;360:333–346. doi: 10.1007/s00441-014-2101-8. PubMed: 25727244.

9. Duval, C., Chagnoleau, C., Pouradier, F., Sextius, P., Condom, E. & Bernerd, F. (2012) Human skin model containing melanocytes: Essential role of keratinocyte growth factor for constitutive pigmentation-functional response to α-melanocyte stimulating hormone and forskolin. Tissue Engineering. Part C, Methods, 18, 947–957. DOI: 10.1089/ten.TEC.2011.0676, PubMed: 22646688.

Regular Issue Subscription Review Article
Volume 14
Issue 01
Received 17/02/2024
Accepted 19/02/2024
Published 30/03/2024
Publication Time 42 Days
366

Login


My IP

PlumX Metrics