A Systematic Review on Coronary Heart Disease: A Transient Ischemic Stroke

Year : 2025 | Volume : 14 | Issue : 03 | Page :
    By

    Manish Sharma,

  • Ashish Kushwaha,

  • Arun Maurya,

  • Lalit Bisht,

  1. Student, Department of Pharmacy, JBIT College of Pharmacy, Shankarpur, Dehradun, Uttarakhand, India
  2. Student, Department of Pharmacy, JBIT College of Pharmacy, Shankarpur, Dehradun, Uttarakhand, India
  3. Student, Department of Pharmacy, JBIT College of Pharmacy, Shankarpur, Dehradun, Uttarakhand, India
  4. Student, Department of Pharmacy, JBIT College of Pharmacy, Shankarpur, Dehradun, Uttarakhand, India

Abstract

Coronary Heart Disease (CHD) and Transient Ischemic Attack (TIA) are significant cardiovascular and cerebrovascular disorders that often share similar risk factors and underlying pathophysiological processes. CHD involves the narrowing or obstruction of the coronary arteries due to atherosclerosis, resulting in diminished blood flow to the heart. A transient ischemic attack (TIA), often called a “mini stroke,” occurs when blood flow to the brain is briefly disrupted, usually due to a clot or embolus. Although TIAs do not result in permanent neurological damage, they serve as significant warning signs of a higher likelihood of future strokes, particularly in individuals with coronary heart disease (CHD). Shared risk factors for both conditions include high blood pressure, diabetes, smoking, obesity, and elevated cholesterol levels. Management strategies for CHD and TIA involve addressing these risk factors through medications like statins and antiplatelet agents, lifestyle changes, and, when necessary, surgical procedures. Early diagnosis, lifestyle adjustments, and proactive treatment are crucial for preventing disease progression and minimizing the risk of serious outcomes such as heart attacks or major strokes. This project focuses on examining the connection between CHD and TIA, their symptoms, diagnostic methods, and approaches to prevention and therapy. Coronary heart disease (CHD) continues to be the leading cause of mortality in Western nations. Identifying the major risk factors associated with the condition is crucial for creating effective strategies for its prevention and management. While nearly 300 variables have been statistically linked to CHD, research indicates that most coronary events can be attributed to a few main factors: high blood pressure, abnormal lipid levels, smoking, and diabetes. Among these, dyslipidemia—particularly elevated low-density lipoprotein (LDL) cholesterol—emerges as a central risk factor. Evidence from laboratory, clinical, and population-based studies suggests that without dyslipidemia, other risk factors have a much smaller impact on overall CHD risk. For instance, countries like China and Japan, which have generally low LDL cholesterol levels, tend to have low rates of CHD, even when smoking and high blood pressure are common.

Keywords: Ischemic Stroke; Atherosclerosis; Coronary Heart Disease; neurological; Management.

[This article belongs to Research and Reviews : Journal of Surgery ]

How to cite this article:
Manish Sharma, Ashish Kushwaha, Arun Maurya, Lalit Bisht. A Systematic Review on Coronary Heart Disease: A Transient Ischemic Stroke. Research and Reviews : Journal of Surgery. 2025; 14(03):-.
How to cite this URL:
Manish Sharma, Ashish Kushwaha, Arun Maurya, Lalit Bisht. A Systematic Review on Coronary Heart Disease: A Transient Ischemic Stroke. Research and Reviews : Journal of Surgery. 2025; 14(03):-. Available from: https://journals.stmjournals.com/rrjos/article=2025/view=233097


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Regular Issue Subscription Review Article
Volume 14
Issue 03
Received 16/05/2025
Accepted 08/09/2025
Published 26/11/2025
Publication Time 194 Days
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