Role Of Autologous Platelet-Rich Plasma (APRP) In Take of Graft


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Year : 2025 | Volume : 14 | Issue : 01 | Page : –
    By

    Mohd Sharib Wahaj,

  • Prof Dr Ravi Kumar Chittoria,

  • Rashmi V Kumar,

  • Padmalakshmi Bharathi Mohan,

  1. Junior Resident, Department of Surgery, Jawaharlal Institute of Post graduate Medical Education and Research (JIPMER), Pondicherry, India
  2. Professor & Registrar (Academic) Head of IT Wing and Telemedicine, Department of Plastic Surgery & Telemedicine Jawaharlal Institute of Post graduate Medical Education and Research (JIPMER), Pondicherry, India
  3. Senior Resident, Department of Plastic Surgery Jawaharlal Institute of Post graduate Medical Education and Research (JIPMER), Pondicherry, India
  4. Assistant Professor, Department of Plastic Surgery Jawaharlal Institute of Post graduate Medical Education and Research (JIPMER), Pondicherry, India

Abstract

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Autologous platelet-rich plasma (APRP) has gained attention as a promising adjunct in skin grafting procedures, particularly in enhancing the take and healing of grafts in burn patients. This study focuses on the application of APRP to improve the adherence of split-thickness skin grafts (STSG) in a paediatric patient with scald burns. APRP is prepared by concentrating the patient’s platelets from a small volume of blood, which is rich in growth factors essential for tissue repair and regeneration. The study describes the preparation process of APRP and its application before STSG to promote graft take. Results showed that the use of APRP significantly improved graft adherence, reduced pain, accelerated healing, and minimized scarring. APRP’s role in wound healing is attributed to the release of growth factors such as PDGF, TGF-β1, and VEGF, which contribute to faster epithelialization and angiogenesis. Furthermore, studies have demonstrated that PRP accelerates wound healing, with superior outcomes compared to traditional methods like sutures or staples. The findings suggest that APRP is a safe, effective, and cost-efficient method for enhancing graft take, offering the additional benefits of a shorter hospital stay and reduced morbidity.

Keywords: APRP, Autologous platelet-rich plasma, Skin graft, Take, Platelets

[This article belongs to Research and Reviews : Journal of Surgery (rrjos)]

How to cite this article:
Mohd Sharib Wahaj, Prof Dr Ravi Kumar Chittoria, Rashmi V Kumar, Padmalakshmi Bharathi Mohan. Role Of Autologous Platelet-Rich Plasma (APRP) In Take of Graft. Research and Reviews : Journal of Surgery. 2025; 14(01):-.
How to cite this URL:
Mohd Sharib Wahaj, Prof Dr Ravi Kumar Chittoria, Rashmi V Kumar, Padmalakshmi Bharathi Mohan. Role Of Autologous Platelet-Rich Plasma (APRP) In Take of Graft. Research and Reviews : Journal of Surgery. 2025; 14(01):-. Available from: https://journals.stmjournals.com/rrjos/article=2025/view=0


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Regular Issue Subscription Original Research
Volume 14
Issue 01
Received 02/12/2024
Accepted 01/01/2025
Published 11/02/2025
46