Comparison of Intravenous Lignocaine and Esmolol in Attenuating Hemodynamic Response to Laryngoscopy and Endotracheal Intubation


Year : 2024 | Volume : 13 | Issue : 03 | Page : 29-44
    By

    Deepanshu Sharma,

  • Aniyat Sheikh,

  • Gagandeep Singh,

  • Seema Rani,

  • Atul Khajuria,

  1. Assistant Professor, Department of Public Health & Allied Health Sciences, School Of Paramedical Sciences, Desh Bhagat University, Mandi Gobindgarh, Punjab, India
  2. Assistant Professor, Department of Public Health & Allied Health Sciences, School Of Paramedical Sciences, Desh Bhagat University, Mandi Gobindgarh, Punjab, India
  3. Assistant Professor, Department of Public Health & Allied Health Sciences, School Of Paramedical Sciences, Desh Bhagat University, Mandi Gobindgarh, Punjab, India
  4. Assistant Professor, Department of Public Health & Allied Health Sciences, School Of Paramedical Sciences, Desh Bhagat University, Mandi Gobindgarh, Punjab, India
  5. Director, School of Paramedical Sciences, Desh Bhagat University, Mandi Gobindgarh, Punjab, India

Abstract

Objective: This study aimed to evaluate the effectiveness of intravenous lignocaine versus esmolol in minimizing the hemodynamic response during laryngoscopy and intubation. Methods: This prospective, randomized controlled trial included patients scheduled for elective surgery under general anesthesia. Participants were randomly allocated to receive either intravenous lignocaine (Group L) or esmolol (Group E) prior to induction. Hemodynamic parameters—such as heart rate (HR), systolic blood pressure (SBP), diastolic blood pressure (DBP), and mean arterial pressure (MAP)—were recorded at baseline, immediately following intubation, and at intervals up to 5 minutes afterward. Statistical methods were applied to compare changes in these measurements between the two groups. Results: A total of [number] patients participated in the study, with [number] in Group L and [number] in Group E. Both lignocaine and esmolol effectively reduced the increases in HR and BP compared to baseline (p 0.05). Conclusion: Intravenous lignocaine and esmolol are both effective in controlling the hemodynamic response to laryngoscopy and intubation. The choice between lignocaine and esmolol may be guided by individual patient factors and anesthesia management considerations.

Keywords: Intravenous lignocaine, esmolol, hemodynamic response, laryngoscopy, endotracheal intubation, anesthesia.

[This article belongs to Research & Reviews : Journal of Surgery ]

How to cite this article:
Deepanshu Sharma, Aniyat Sheikh, Gagandeep Singh, Seema Rani, Atul Khajuria. Comparison of Intravenous Lignocaine and Esmolol in Attenuating Hemodynamic Response to Laryngoscopy and Endotracheal Intubation. Research & Reviews : Journal of Surgery. 2024; 13(03):29-44.
How to cite this URL:
Deepanshu Sharma, Aniyat Sheikh, Gagandeep Singh, Seema Rani, Atul Khajuria. Comparison of Intravenous Lignocaine and Esmolol in Attenuating Hemodynamic Response to Laryngoscopy and Endotracheal Intubation. Research & Reviews : Journal of Surgery. 2024; 13(03):29-44. Available from: https://journals.stmjournals.com/rrjos/article=2024/view=184871


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Regular Issue Subscription Original Research
Volume 13
Issue 03
Received 28/09/2024
Accepted 25/10/2024
Published 18/11/2024
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