The Effect of the Treatment by Combining Hyaluronic Acid (HA) Filler and Botulinum Toxin A (BTX-A) on the Upper Face

Open Access

Year : 2022 | Volume : | Issue : 1 | Page : 34-40
By

    Gang-Ho Jong

  1. Hak-Bom Han

  2. Hui-Chol Kang

  1. Researcher, Department of Medicine, Pyongyang Medical University, Pyongyang, Democratic People’s Republic of Korea
  2. Researcher, Department of Medicine, Pyongyang Medical University, Pyongyang, Democratic People’s Republic of Korea
  3. Researcher, Department of Medicine, Pyongyang Medical University, Pyongyang, Democratic People’s Republic of Korea

Abstract

Recently, more people have better aesthetic satisfactions with the application of various treatment methods. Especially, development of botulinum toxins and facial fillers provide patients having folds with new hopes. Aims: We studied to clarify the aesthetic effect of the treatment by combining the injectable hyaluronic acid (HA) and botulinum toxin A (BTX-A). Setting and designs: 115 patients complaining about folds in foreheads, glabellars, and lateral periorbital regions were selected. We made two groups; control group was treated only with injectable HA filler and experimental group by combining HA and BTX-A. Both groups were followed for 8 months after injection. Material and methods: HA (Restylane) and BTX-A were together applied to the upper face folds including forehead, glabellar and crow’s feet that were represented by mimetic muscles. We evaluated the correction and the maintenance effects in control and experimental groups at 0 and 8 months after treatments. Statistical analysis used: All the experimental values were analyzed statistically with Student’s t-test of Microsoft Excel 2013. Results: All the patients in both groups had efficient fold corrections, but there was no significant difference of the rate of maintenance between 2 groups. Conclusion: On the upper face, combined treatments with the injectable HA and BTX-A were intended to have better early effects than with only a filler, and the combined procedure didn’t have a significant difference in fold correction maintenance effects after 8 months.

Keywords: Facial filler, Hyaluronic acid, Facial fold, Botulinum toxin, HA and BTX-A

[This article belongs to Research & Reviews : Journal of Surgery(rrjos)]

How to cite this article: Gang-Ho Jong, Hak-Bom Han, Hui-Chol Kang The Effect of the Treatment by Combining Hyaluronic Acid (HA) Filler and Botulinum Toxin A (BTX-A) on the Upper Face rrjos 2022; 11:34-40
How to cite this URL: Gang-Ho Jong, Hak-Bom Han, Hui-Chol Kang The Effect of the Treatment by Combining Hyaluronic Acid (HA) Filler and Botulinum Toxin A (BTX-A) on the Upper Face rrjos 2022 {cited 2022 Feb 21};11:34-40. Available from: https://journals.stmjournals.com/rrjos/article=2022/view=91765

Full Text PDF Download

Browse Figures

References

1. Rzany B. Injectable Fillers in Aesthetic Medicine. Springer-Verlag Berlin Heidelberg 2006 Printed in Germany; 23–82pp.
2. Costa C. R, et al. Advances and Refinement in Hyaluronic Acid Facial Fillers, Plast Reconstr Surg. 2016; 138 (2); 233e-6.
3. Fabrizio Duranti, Giovanni Salti, Bruno Bovani, Mario Calandra, Maria Laura Rosati. Injectable Hyaluronic Acid Gel for Soft Tissue Augmentation. Inc Dermatol Surg. 1998; 24 (12); 1317–25.
4. Frampton JE. Botulinum Toxin A(Botox Cosmetic): A Review of its use in the Treatment of Glabellar Frown Lines. Am J Clin Dermatol. 2003; 4 (10): 709–25
5. Seth L. Matarasso, Jean D. Carruthers, Mark L. Jewell. Consesus Recommendation for Soft Tissue Augmentation With Stabilized Hyaluronic Acid (Restylane). Plast Reconstr Surg. 2006 Mar; 117 (3 Suppl): 3S–34S.
6. Sundaram H, Liew S, Signorini M, Vieira Braz A, Fagien S, Swift A et al. Global Aesthetics Consensus Hyaluronic Acid Fillers and Botulinum Toxin Type A-Recommendations for Combined Treatment and Optimizing Outcomes in Diverse Patient Populations. Plast Reconstr Surg. 2016; 137 (5); 1410–1423.
7. Wu WT, Liew S, Chan HH, Ho WW, Supapannachart N, Lee HK, et al. Consensus on Current Injectable Treatment Strategies in the Asian Face. Asian Facial Aesthetics Expert Consensus Group.
Aesthetic Plast Surg. 2016; 40 (2); 202–14.


Regular Issue Open Access Article
Volume 11
Issue 1
Received September 27, 2021
Accepted February 14, 2021
Published February 21, 2022