Sudipta Roy
- Assistant Professor, Bengal College of Pharmaceutical Technology, West Bengal, India
Abstract
A phytosome is a complex created through the union of a natural compound, typically a plant extract, with a phospholipid. Phospholipids play a crucial role in cell membranes, possessing a structure comprising a hydrophilic (water-attracting) head and hydrophobic (water-repelling) tails. This distinctive structure enables phospholipids to construct lipid bilayers, fundamental elements of cell membranes. Phytosome increases the bioavailability, absorption of active chemical constituents in the extract with the help of hydrophobic tails of the phospholipid interacting with lipids in digestive system enhancing the absorption. Applications of Phytosome are in making the formulation of dietary supplements and herbal extracts, to improve the delivery of bioactive compounds, increasing the absorption of phytochemicals for easy accessibility to the body, in the realms of herbal medicine and nutritional supplements, focusing the significance of optimizing the absorption of bioactive compounds for therapeutic effects. Nevertheless, it is crucial to acknowledge that ongoing research explores the effectiveness and advantages of phytosomes, and individual responses to products containing phytosomes may vary. The primary objective is to enhance the absorption of phytochemicals, making them more easily accessible for utilization by the body. As this field progresses, phytosomes emerge as leaders in innovative strategies to enhance the effectiveness of natural compounds across diverse applications.
Keywords: Azadirachta indica, Aqueous Extract, Phytosome, Novel Drug Delivery System, Formulation, Evaluation, Azadirachta indica phytosome.
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Research & Reviews: A Journal of Pharmacognosy
| Volume | |
| Received | February 27, 2024 |
| Accepted | March 26, 2024 |
| Published | April 8, 2024 |