Swarnima Pandey,
Shivam Pathak,
Ankit Verma,
Sanjog Pal Singh,
- Principal, Apex College of Pharmacy, Rampur, Uttar Pradesh, India
- Student, Department of Pharmacy, Apex College of Pharmacy, Rampur, Uttar Pradesh,
- Student, Department of Pharmacy, Apex College of Pharmacy, Rampur, Uttar Pradesh, India
- Student, Department of Pharmacy, Apex College of Pharmacy, Rampur, Uttar Pradesh, India
Abstract
Adverse drug reaction (ADR) is an unfavorable event with a causal connection to the medication. It is an undesirable event occurred by a pharmacological substance. They are a major cause of Mortality all over, they are classified into augmented, chronic, bizarre, Delayed based on the severity of the damage they caused The primary causes of adverse drug reactions (ADRs) are drug overdose, drug– drug interactions, genetic variations, and individual characteristics such as age, sex, and the presence of disease. Pharmacovigilance plays a key role in determination and prevention of ADRs. ADR monitoring and reporting is crucial because of the increasing number of ADR cases in our country. Timely reporting of ADR to regulatory authorities is important for drug monitoring, patient safety, and to identify the therapeutic range of medicines. In this review authors have covered different aspects of ADRs.
Keywords: Bizarre reactions, Drug- Drug Interactions, Primary care, Patient monitoring
[This article belongs to Research and Reviews: A Journal of Pharmacology ]
References
1. Jeffrey KA, Robin EF. Clarification of terminology in drug safety. Drug Safe. 2005; 28:851-70.
2. U.S. FDA, Guidance for Industry Good Pharmacovigilance Practices and Pharmacoepidemiologic Assessment, Center for Drug Evaluation and Research and Center for Biologics Evaluation and Research, Rockville, MD, March 2005.
3. AbubakarAR, SimbakNB, Haque M. Adverse Drug Reactions: predisposing factors, modern classifications and causality assessment. Research J. Pharm. 2014; 7(9):1091-1098.
4. EdwardsIR, Jeffrey KA. Adverse drug reactions: definitions, diagnosis, and management. The Lancet. 2000; 255-59.
5. Dhikav V, SinghS, Anand KS. Adverse Drug Reaction Monitoring In India. JIACM 2004;
6(1): 27-33.5.PallaschTJ. Principles of Pharmacotherapy V. Toxicology and Adverse Drug Reactions. Anesth Prog. 1989;36:41-45.
7. Phillips KA, Veenstra DL, Oren E, Potential role of pharmacogenomics in reducing adverse drug reactions: A systematic review, JAMA, 2001, 4:2270-2279.
8.LavanAH, Gallagher P. Predicting risk of adverse drug reactions in older adults. Ther Adv Drug Saf.2016;7(1):11
9. Tripathi K. Text book of Pharmacology. Jaypee Brothers Medical publishers Pvt. Ltd.2013: 218-222
10. W Roger, Whittle C. Clinical pharmacy and Therapeutics. Churchill Livingstone Elsevier; 2007: 51-60.
11. Ragoonanan D.KhazalS. J.Abdel-AzimH.McCallD.Cuglievan B. TambaroF. P.et al (2021). Diagnosis, grading and management of toxicities from immunotherapies in children, adolescents and young adults with cancer. Nat. Rev. Clin. Oncol.18 (7), 435–453. 10.1038/s41571-021-00474-4
12. PittsP. J.LouetH. L.MorideY.ContiR. M. (2016). 21st century pharmacovigilance: efforts, roles, and responsibilities. Lancet Oncol.17 (11), e486–e492. 10.1016/S1470-2045(16)30312-6
Research and Reviews: A Journal of Pharmacology
| Volume | 16 | |
| Issue | 02 | |
| Received | 28/03/2026 | |
| Accepted | 02/04/2026 | |
| Published | 24/04/2026 | |
| Publication Time | 27 Days |