Gazal Rani,
- Research Scholar, Department of Engineering and Technology, Chitkara University, Rajpura, Punjab, India
Abstract
Parkinson’s disease (PD) is a long-term, progressive neurodegenerative disorder that mainly occurs in people older than 60 years, affecting nearly 1% of this population. It is chiefly marked by the loss of dopaminergic neurons in the substantia nigra, a crucial brain region responsible for controlling motor functions. The resultant dopamine deficiency significantly disrupts motor control, manifesting in clinical symptoms such as tremors, bradykinesia, muscle rigidity, and postural instability. While PD severely impacts patients’ quality of life, early detection and appropriate management strategies can lead to significantly improved outcomes. Despite considerable scientific and technological progress, a definitive cure for Parkinson’s disease has not yet been found. Nevertheless, the progressive course of PD highlights the critical need for early diagnosis and prompts therapeutic interventions to slow symptom advancement and enhance quality of life. In recent years, artificial intelligence (AI) has gained prominence as a powerful tool in various domains, including healthcare, where it holds significant promise for improving the diagnosis, treatment, and overall management of PD. This paper presents an in-depth exploration of the various ways AI can be applied in the diagnosis, therapeutic planning, and clinical management of Parkinson’s disease. AI-powered wearable devices, smartphone applications, machine learning (ML) algorithms, and natural language processing (NLP) technologies have demonstrated remarkable potential in facilitating early detection and real-time symptom monitoring in PD patients. Additionally, the integration of AI in PD management raises challenges, such as data privacy concerns and the need for extensive databases, to enhance diagnostic accuracy and treatment efficacy. This paper also explores these challenges, emphasizing the need for robust data security protocols and the development of large, reliable datasets to optimize AI applications in PD care.
Keywords: Parkinson’s disease (PD), neurodegenerative disorder, dopaminergic neurons, substantia nigra, motor symptoms, early diagnosis, therapeutic intervention, quality of life, artificial intelligence (AI)
[This article belongs to Research and Reviews: A Journal of Neuroscience ]
Gazal Rani. A Review on Applications of Artificial Intelligence (AI) in Parkinsons’s Disease Diagnosis and Treatment and Its Future Challenges. Research and Reviews: A Journal of Neuroscience. 2025; 15(03):1-15.
Gazal Rani. A Review on Applications of Artificial Intelligence (AI) in Parkinsons’s Disease Diagnosis and Treatment and Its Future Challenges. Research and Reviews: A Journal of Neuroscience. 2025; 15(03):1-15. Available from: https://journals.stmjournals.com/rrjons/article=2025/view=233472
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Research and Reviews: A Journal of Neuroscience
| Volume | 15 |
| Issue | 03 |
| Received | 27/05/2025 |
| Accepted | 02/07/2025 |
| Published | 05/12/2025 |
| Publication Time | 192 Days |
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