Excoecaria Agallocha Extract from Leaves Encounters Antifungal, Antibacterial, and Cytotoxic Activity – In Vitro Studies.

Year : 2025 | Volume : 15 | Issue : 02 | Page : 1-8
    By

    P. Kumar,

  • K. Karthikeyan,

  1. Assistant Professor, Department of Food Science and Nutrition, Periyar University, Salem, Tamil Nadu, India
  2. Guest Faculty, Department of Enviromental Science and Management , Bharthidasan University, Tiruchirappalli, Tamil Nadu, India

Abstract

Mangroves contain a wide range of bioactive substances, certain of and these have been used as solutions for a variation of conditions for thousands of years. Excoecaria agallocha leaf application components have been extracted in the presence of organic solvents along with water-based with a Soxhlet apparatus and antibacterial research properties employing diffusion agar well assays towards nine different kinds of culture infectious agents, six clinical trials isolated compounds, as well as two pathogenic fungal organisms. The extracts were subsequently evaluated for brine-shrimp the cytotoxicity employing Artemia salina. Thin-layer chromatography, or TLC, as well as infrared spectroscopy with a Fourier transform (FT-IR) have been utilised for investigating the chemical elements. The antimicrobial property of ethyl acetate extract became extremely various. The isolates of Staphylococcus aureus have been shown to have been especially susceptible within clinical appointments as well as type-culture combinations, alongside zones of resistance observing 17.31.1 and 23.51.3 mm in diameter, correspondingly. Candida albicans and Candida tropicalis, on the contrary, possessed lesser anticandidal action (10.30.6 and 11.90.85 mm diameter, respectively). The limit of detection (LD50) for cytotoxic activity was 521 g/mL. Bioassay-guided (antibacterial) TLC demonstrated that there was an abundance of an essential energetic component F2, which are combinations which are combinations with an Rf of 1.21, as well as FT-IR measurements on this portion of the solution indicated it was squalene, which might play an essential function in the chemical security mechanism.

Keywords: This compound, mangrove forests, extracted from plants, and antibacterial abilities are all mentioned. Bioactive substance, cytotoxicity.

[This article belongs to Research and Reviews: A Journal of Microbiology and Virology ]

How to cite this article:
P. Kumar, K. Karthikeyan. Excoecaria Agallocha Extract from Leaves Encounters Antifungal, Antibacterial, and Cytotoxic Activity – In Vitro Studies.. Research and Reviews: A Journal of Microbiology and Virology. 2025; 15(02):1-8.
How to cite this URL:
P. Kumar, K. Karthikeyan. Excoecaria Agallocha Extract from Leaves Encounters Antifungal, Antibacterial, and Cytotoxic Activity – In Vitro Studies.. Research and Reviews: A Journal of Microbiology and Virology. 2025; 15(02):1-8. Available from: https://journals.stmjournals.com/rrjomv/article=2025/view=202416


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Regular Issue Subscription Original Research
Volume 15
Issue 02
Received 04/01/2025
Accepted 17/01/2025
Published 04/02/2025
Publication Time 31 Days
Total Visits: 146


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