Hearing, Speech, and Language Characteristics in a Case with Hemoglobinopathy Secondary to Beta Thalassemia Intermedia

Year : 2025 | Volume : 14 | Issue : 01 | Page : 1 5
    By

    Pavan Katti,

  • Sabarish A,

  • Varun S B,

  • Sejal Mahajan,

  1. Assistant Professor, Department of Audiology, JSS Institute of Speech and Hearing, Nehru Nagar, Dharwad, Karnataka, India
  2. Assistant Professor, Department of Audiology, JSS Institute of Speech and Hearing, Nehru Nagar, Dharwad, Karnataka, India
  3. Internship Students, Department of Audiology, JSS Institute of Speech and Hearing, Nehru Nagar, Dharwad, Karnataka, India
  4. Internship Students, Department of Audiology, JSS Institute of Speech and Hearing, Nehru Nagar, Dharwad, Karnataka, India

Abstract

Background: Thalassemia is an inherited disorder characterized by a reduced amount or absence of hemoglobin, the oxygen-carrying protein inside the red blood cell. Thalassemia has its types called alpha and beta-thalassemia. Beta thalassemia is a condition in which there is a reduction or deficit in the synthesis of the beta-globin chain of hemoglobin molecules caused by a mutation in chromosome eleven. Beta thalassemia can be broadly categorized into three main categories: beta thalassemia minor, intermedia, and major. Hearing loss is a predominant trait in cases with beta-thalassemia intermedia and major. Understanding the pathophysiology of thalassemia is important for the management of these individuals. Hence there is a strong need for audiological and speech-language evaluation in them. Thus, this case report highlights the audiological, speech, and language findings in beta thalassemia intermedia. Case Description: Routine audiological and speech and language evaluation was carried out. Pure Tone Audiometry showed moderate mixed hearing loss in the right and severe sensorineural hearing loss in the left ear. Speech and language evaluation revealed delayed receptive and expressive abilities due to Hearing impairment. Conclusion: The present case report highlights the effect of Non-Transfusion Dependent treatment received by beta thalassemia intermedia patients on speech, language, and hearing abilities. The present case report also suggests that ongoing treatment of thalassemia may be a cause of hearing loss progression. Hence, periodic monitoring of hearing, speech and language skills is essential in individuals with thalassemia.

Keywords: Beta-thalassemia, hemoglobinopathy, hearing loss, thalassemia intermedia, non-transfusion dependent treatment

[This article belongs to Research and Reviews : A Journal of Medical Science and Technology ]

How to cite this article:
Pavan Katti, Sabarish A, Varun S B, Sejal Mahajan. Hearing, Speech, and Language Characteristics in a Case with Hemoglobinopathy Secondary to Beta Thalassemia Intermedia. Research and Reviews : A Journal of Medical Science and Technology. 2025; 14(01):1-5.
How to cite this URL:
Pavan Katti, Sabarish A, Varun S B, Sejal Mahajan. Hearing, Speech, and Language Characteristics in a Case with Hemoglobinopathy Secondary to Beta Thalassemia Intermedia. Research and Reviews : A Journal of Medical Science and Technology. 2025; 14(01):1-5. Available from: https://journals.stmjournals.com/rrjomst/article=2025/view=197018


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Regular Issue Subscription Case Study
Volume 14
Issue 01
Received 06/12/2024
Accepted 18/12/2024
Published 05/02/2025
Publication Time 61 Days
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