Mohd. Farhan,
Nalini Kanta Sahoo,
Alex Martin,
Rajesh Nath,
Asad Jamal Ansari,
Ebadurrahman,
Saurabh Kumar Chauhan,
- Researcher, Faculty of Pharmaceutical Sciences, Rama University, Kanpur, Uttar Pradesh, India
- Researcherq, Faculty of Pharmaceutical Sciences, Rama University, Kanpur, Uttar Pradesh, India
- Researcher, Faculty of Pharmaceutical Sciences, Rama University, Kanpur, Uttar Pradesh, India
- Researcher, Faculty of Pharmaceutical Sciences, Rama University, Kanpur, Uttar Pradesh, India
- Researcher, Faculty of Pharmacy, Integral University, Lucknow, Uttar Pradesh, India
- Researcher, Department of Pharmacology, College of Pharmacy, Integral University, Lucknow, Uttar Pradesh, India
- Researcher, Department of Pharmacology, School of Pharmaceutical Education and Research (SPER), Jamia Hamdard, New Delhi, India
Abstract
Background: Endocrine disorders affecting the thyroid gland represent some of the most frequently encountered conditions globally, necessitating prolonged therapeutic intervention and vigilant clinical surveillance. The evaluation of Drug utilization patterns (DUE) serves an essential function in examining prescriptive behaviours and promoting appropriate pharmaceutical management. Objective: To evaluate drug utilization patterns, prescribing trends, and rationality of therapy in patients with hypothyroidism and hyperthyroidism. Methods: A prospective, cross-sectional observational investigation was performed across six months within the ambulatory care division of a tertiary healthcare facility. The study encompassed 200 patients with confirmed thyroid pathology. Data were collected from prescriptions and patient interviews and analysed using WHO prescribing indicators. Results: Among 200 patients, hypothyroidism was more prevalent (70%) than hyperthyroidism (30%), with a higher proportion of females (70%). Levothyroxine was the most commonly prescribed drug in hypothyroid patients, while carbimazole was predominantly used in hyperthyroidism. Co-prescription of calcium and iron supplements was frequent. Mild polypharmacy (25%) and drug–drug interactions, particularly involving levothyroxine, were observed. Prescribing practices were largely consistent with clinical guidelines. Conclusion: The study demonstrates largely rational prescribing patterns in thyroid disorder management. However, improved monitoring and awareness of drug interactions are essential to optimize therapeutic outcomes.
Keywords: Drug utilization, hypothyroidism, hyperthyroidism, levothyroxine, carbimazole, who prescribing indicators
[This article belongs to Research and Reviews: A Journal of Medicine ]
Mohd. Farhan, Nalini Kanta Sahoo, Alex Martin, Rajesh Nath, Asad Jamal Ansari, Ebadurrahman, Saurabh Kumar Chauhan. Evaluation of Drug Utilization Patterns and Prescription Trends in Patients with Hypothyroidism and Hyperthyroidism in a Tertiary Care Hospital. Research and Reviews: A Journal of Medicine. 2026; 16(02):1-5.
Mohd. Farhan, Nalini Kanta Sahoo, Alex Martin, Rajesh Nath, Asad Jamal Ansari, Ebadurrahman, Saurabh Kumar Chauhan. Evaluation of Drug Utilization Patterns and Prescription Trends in Patients with Hypothyroidism and Hyperthyroidism in a Tertiary Care Hospital. Research and Reviews: A Journal of Medicine. 2026; 16(02):1-5. Available from: https://journals.stmjournals.com/rrjom/article=2026/view=249698
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Research and Reviews: A Journal of Medicine
| Volume | 16 |
| Issue | 02 |
| Received | 09/04/2026 |
| Accepted | 14/04/2026 |
| Published | 15/07/2026 |
| Publication Time | 97 Days |
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