Decoding Innate Immunity: Mechanisms, Components, and Clinical Implication

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Year : 2025 | Volume : 15 | Issue : 02 | Page :
    By

    V Hans,

  1. Research Professor, Department of Management and Commerce, Srinivas University, Mangalore, Karnataka, India

Abstract

Innate immunology represents the body’s first line of defense against pathogens, acting as a rapid, non-specific response to a wide array of microbial invaders. This part of the immune system depends on pattern recognition receptors (PRRs) to identify pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs), leading to the activation of immune cells such as macrophages, dendritic cells, and neutrophils. The innate immune system also plays a crucial role in bridging the gap to adaptive immunity, facilitating the development of a more specific and long-term immune response. Additionally, recent studies have illuminated the complexity of innate immune regulation, uncovering its involvement in inflammatory diseases, tissue homeostasis, and even the modulation of cancer progression. This article reviews the key components and mechanisms of innate immunity, highlighting the importance of early immune responses, their contribution to disease, and the ongoing research into therapeutic interventions targeting innate immune pathways for improved health outcomes.

Keywords: Innate immune regulation, immune pathways, recognition receptor, antigen presentation

[This article belongs to Research and Reviews : A Journal of Immunology ]

How to cite this article:
V Hans. Decoding Innate Immunity: Mechanisms, Components, and Clinical Implication. Research and Reviews : A Journal of Immunology. 2025; 15(02):-.
How to cite this URL:
V Hans. Decoding Innate Immunity: Mechanisms, Components, and Clinical Implication. Research and Reviews : A Journal of Immunology. 2025; 15(02):-. Available from: https://journals.stmjournals.com/rrjoi/article=2025/view=211481


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Regular Issue Subscription Review Article
Volume 15
Issue 02
Received 06/04/2025
Accepted 07/04/2025
Published 27/05/2025
Publication Time 51 Days
234

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