Development and Evaluation of Medicated Mouth Wash

Year : 2026 | Volume : 15 | Issue : 01 | Page : 21 30
    By

    Sandeep Gadhwe,

  • Gautam Palshikar,

  1. Assistant Professor, Department of Pharmaceutical Chemistry, Sinhgad College of Pharmacy, Pune, Maharashtra, India
  2. Assistant Professor, Department of Pharmacognosy, Genba Sopanrao Moze College of Pharmacy, Pune, Maharashtra, India

Abstract

The present invention is to formulate and evaluate a novel medicated mouth rinse using Achyranthes aspera extract in an oil-based formulation. The herb Achyranthes aspera, which has long been used for medicinal purposes, was chosen because of its purported anti-inflammatory and antibacterial qualities. This study aimed to create a safe, effective, and pleasant-tasting mouth rinse to maintain oral hygiene and address common oral health issues. Achyranthes aspera’s bioactive components were extracted and added to an oil-based carrier solution during the formulation process. To increase therapeutic potential while ensuring user acceptance, this novel mouthwash was enhanced with complementing natural essential oils. The evaluation study is based on Thin Layer Chromatography, pH, Gram staining, the determination of acid value and specific gravity. Additionally, research has found significant antimicrobial properties leading to their usefulness in treating common oral issues. This study advances the creation of a novel mouthwash that could be therapeutic by utilizing the oil-based medicinal properties of Achyranthes aspera. It is a plant species that is classified as a weed or wildflower. This plant can grow in tropical climates without needing to be started from seed. This plant is a weed, but it offers many, immediate, and unexpected health benefits. Eating Achyranthes seeds can aid in weight loss since they contain substances that help your body burn fat. This herb can also be very helpful for digestion. The formulation is bacteriostatic in nature which shows that it prohibits the growth of bacteria. It was made using Achyranthes aspera, which has capacity to reduce or prohibit dental caries. It is mainly based on an ancient method which is oil pulling. An alternative medicinal procedure called “oil pulling” involves swishing edible oil about the mouth for a while before spitting it out, much like mouthwash.

Keywords: Achyranthes aspera, anti-inflammatory, mouth rinse, natural, oral issues

[This article belongs to Research & Reviews : Journal of Herbal Science ]

How to cite this article:
Sandeep Gadhwe, Gautam Palshikar. Development and Evaluation of Medicated Mouth Wash. Research & Reviews : Journal of Herbal Science. 2025; 15(01):21-30.
How to cite this URL:
Sandeep Gadhwe, Gautam Palshikar. Development and Evaluation of Medicated Mouth Wash. Research & Reviews : Journal of Herbal Science. 2025; 15(01):21-30. Available from: https://journals.stmjournals.com/rrjohs/article=2025/view=241029


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Regular Issue Subscription Original Research
Volume 15
Issue 01
Received 12/09/2025
Accepted 03/12/2025
Published 05/12/2025
Publication Time 84 Days
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