Intermittent Fasting: Exploring the Benefits and Risks of Intermittent Fasting for Weight Loss and Overall Health

Year : 2025 | Volume : 14 | Issue : 03 | Page : 24 29
    By

    J. Samuel Kamanda,

  • Atul Khajuria,

  • Eric Kwasi Elliason,

  • Stephen Monday,

  1. Teaching Assistant, Faculty of Allied Health Sciences, Desh Bhagat University, Mandi Gobindgarh, Punjab, India
  2. Director, Faculty of Allied Health Sciences, Desh Bhagat University, Mandi Gobindgarh, Punjab, India
  3. Teaching Assistant, Faculty of Allied Health Sciences, Desh Bhagat University, Mandi Gobindgarh, Punjab, India
  4. Teaching Assistant, Faculty of Allied Health Sciences, Desh Bhagat University, Mandi Gobindgarh, Punjab, India

Abstract

Perception in Intermittent Fasting: One novel approach for managing weight is intermittent fasting (IF) which is gaining more popularity in recent days. This research investigates advantages and disadvantages of IF with an emphasis on its impact on metabolic processes, cardiovascular health, cognitive abilities, and changes in hormone levels. Methods: A literature review comprising randomized clinical trials, cohort studies, and meta-analyses of peer-reviewed publications was performed. A resolution was obtained by utilizing studies complying with institutional and international norms. Comparisons of effect sizes, confidence intervals (CIs), and P values for evaluating the efficacy and risks associated with alternating IF regimens (for instance, 16/8 and 5:2) were undertaken through statistical analysis. Results: Our analysis shows IF leads to better metabolic adaptation with significantly higher insulin sensitivity (OR = 1.45, 95% CI 1.30–1.61, P < .001) and cardiovascular health (lowered LDL cholesterol, OR=1.32, 95% CI 1.18–1.47, P < .001). Autophagy along with decreased inflammation enhanced IF and longevity. Enhanced mental clarity, lowered neurodegenerative diseases (OR = 1.28, 95% CI 1.14–1.43, P < .001) were also noted as cognitive benefits. On the other hand, prolonged fasting periods posed risks, such as nutritional deficiency, hormonal imbalance, and other unexplored consequences. Conclusions: As an effective method of dietary practice, Intermittent Fasting (IF) shows promise in promoting health and improving weight; however, tailored approaches are critical to avoid negative outcomes. More research is needed to provide tailored approaches to intermittent fasting to ensure sustained safety and encounter minimal risks over time. Take-Home Message: Intermittent fasting has potential benefits beyond aiding calorie restriction as it may aid in weight management, enhance metabolic function, and improve cognitive abilities. However, IF variations need to be made for each person to lessen the chance of harm, including hormonal disruption, nutritional scarcity, or undernourishment. More tailored studies are urgently needed to adjust IF for sustained health.

Keywords: Autophagy, cardiovascular health, cognitive function, dietary interventions, fasting methods, insulin sensitivity, intermittent fasting, metabolic health, nutritional deficiencies, weight loss

[This article belongs to Research & Reviews : Journal of Herbal Science ]

How to cite this article:
J. Samuel Kamanda, Atul Khajuria, Eric Kwasi Elliason, Stephen Monday. Intermittent Fasting: Exploring the Benefits and Risks of Intermittent Fasting for Weight Loss and Overall Health. Research & Reviews : Journal of Herbal Science. 2025; 14(03):24-29.
How to cite this URL:
J. Samuel Kamanda, Atul Khajuria, Eric Kwasi Elliason, Stephen Monday. Intermittent Fasting: Exploring the Benefits and Risks of Intermittent Fasting for Weight Loss and Overall Health. Research & Reviews : Journal of Herbal Science. 2025; 14(03):24-29. Available from: https://journals.stmjournals.com/rrjohs/article=2025/view=229517


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Regular Issue Subscription Original Research
Volume 14
Issue 03
Received 02/04/2025
Accepted 19/07/2025
Published 22/07/2025
Publication Time 111 Days
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