Lone Musharaf Manzoor,
- Researcher, Department of Health and Allied Sciences Guru Kashi University Bathinda, Punjab, India
Abstract
AI is changing (and will change) healthcare as we know it, and diagnostics might be the specialty that feels the most discomfort. Artificial intelligence-based analytical systems are facilitating the detection, diagnosis, and treatment of a variety of diseases, with better accuracy, speed, and results. Now, this abstract investigates the role of AI in diagnostics, scouring its elements, landmark techniques, transformative impact and future overview. This article explains AI and discusses its application in different aspects of healthcare with a specific focus on diagnostics. From medical images and laboratory results to genomic data and electronic health records, these algorithms are able to sort through an unprecedented amount of data to assist healthcare professionals in making more accurate and timely diagnostic decisions. By enabling rapid, high-precision analysis and response — whether it`s identifying small differences visible in medical images lumbering to assess the likelihood of pathology and prognosis from genetic maps — AI is expanding human vision & striking even higher diagnostic accuracy. Various AI applications are used in diagnostics across a spectrum of medical specialties. AI-powered algorithms analyze medical images to identify and characterize abnormalities in radiology. In pathology, AI algorithms automate the analysis of tissue samples, aiding pathologists to identify malignant cells. AI simplifies complex genetic data interpretation in genomics, paving the way for personalized medicine. AI also aids in point-of-care diagnostics for fast and accurate testing. AI assistance in diagnostic workflows helps improve the accuracy, decrease the error rates and promote the patient safety. It facilitates the same-day diagnosis, decreases turnaround times, and enhances access to care. AI also frees up healthcare professionals by automating repetitive tasks, leaving them to tend to complex cases and interaction with patients. What’s more, thanks to AI, diseases can be detected earlier on and treated more effectively. The potential is there, but obstacles still exist. The need for generalizability of AI models to other patient populations is paramount. The biggest challenge lies in addressing ethical concerns like data privacy and algorithmic bias. It is essential to build trust between healthcare professionals as well as patients. With the AI landscape in healthcare constantly evolving, clear guidelines are required. Ground-breaking technologies like federated learning and explainable AI are set to provide even greater improvements to AI-powered diagnostic systems. Further studies are necessary to surmount these challenges and realize the full promise of AI in diagnostics. With effective collaboration and evaluation, AI can leverage quality healthcare through smart decision-making and the security of medical investments that leads to better health and well-being.
Keywords: Artificial intelligence, diagnostics, machine learning, radiology, pathology, genomics, point-of-care, accuracy, efficiency, challenges, future prospects
[This article belongs to Research and Reviews: A Journal of Health Professions ]
Lone Musharaf Manzoor. Artificial Intelligence in Diagnostics: Advancements, Challenges, and Future Prospects. Research and Reviews: A Journal of Health Professions. 2025; 15(03):8-17.
Lone Musharaf Manzoor. Artificial Intelligence in Diagnostics: Advancements, Challenges, and Future Prospects. Research and Reviews: A Journal of Health Professions. 2025; 15(03):8-17. Available from: https://journals.stmjournals.com/rrjohp/article=2025/view=230521
References
- Kulkarni S, Seneviratne N, Baig MS, Khan A. Artificial Intelligence in Medicine: Where Are We Now? Acad Radiol. 2019 Oct 19;27(1):62. doi: 10.1016/j.acra.2019.10.001.
- Khan B, et al. Drawbacks of Artificial Intelligence and Their Potential Solutions in the Healthcare Sector. Deleted J. 2023 Feb 8;1(2):731. doi: 10.1007/s44174-023-00063-2.
- Bhandari A. Revolutionizing Radiology With Artificial Intelligence. Cureus. 2024;16(10):e72646. doi: 10.7759/cureus.72646.
- Létourneau‐Guillon L, Camirand D, Guilbert F, Forghani R. Artificial Intelligence Applications for Workflow, Process Optimization and Predictive Analytics. Neuroimaging Clin N Am. 2020 Oct 7;30(4). doi: 10.1016/j.nic.2020.08.008.
- van Hartskamp M, Consoli S, Verhaegh W, Petković M, van de Stolpe A. Artificial Intelligence in Clinical Health Care Applications: Viewpoint. J Med Internet Res. 2019 Jan 31;21(2):e12100. doi: 10.2196/12100.
- Alami H, et al. Artificial Intelligence and Health Technology Assessment: Anticipating a New Level of Complexity. J Med Internet Res. 2020 May 13;22(7):e17707. doi: 10.2196/17707.
- Kelly C, Karthikesalingam A, Suleyman M, Corrado GS, King D. Key challenges for delivering clinical impact with artificial intelligence. BMC Med. 2019 Oct 29;17:195. doi: 10.1186/s12916-019-1426-2.
- Mayo RC, Sen LQC, Leung JWT. Financing Artificial Intelligence in Medical Imaging: Show Me the Money. J Am Coll Radiol. 2020 Jan;17(1 Pt A):65-70. doi: 10.1016/j.jacr.2019.07.004.
- Vilhekar RS, Rawekar A. Artificial Intelligence in Genetics. Cureus. 2024 Jan 10;16(1):e52035. doi: 10.7759/cureus.52035.
- Al-antari MA. Artificial Intelligence for Medical Diagnostics—Existing and Future AI Technology! Diagnostics (Basel). 2023 Feb 12;13(4):688. doi: 10.3390/diagnostics13040688.
- Aftab MN, et al. AI in Oncology: Transforming Cancer Detection through Machine Learning and Deep Learning Applications. arXiv [Preprint]. 2025 Jan 26. doi: 10.48550/arxiv.2501.15489.
- Verma V, et al. A novel hybrid model integrating MFCC and acoustic parameters for voice disorder detection. Sci Rep. 2023 Dec 20;13:49869. doi: 10.1038/s41598-023-49869-6.
- Leiner T, Bennink E, Mol CP, Kuijf HJ, Veldhuis WB. Bringing AI to the clinic: blueprint for a vendor-neutral AI deployment infrastructure. Insights Imaging. 2021 Feb 2;12(1):19. doi: 10.1186/s13244-020-00931-1.
- Rahman, Islam MS, Moon MJ, Tasnim T, Siddique N, Ahmed S. A Qualitative Survey on Deep Learning Based Deep Fake Video Creation and Detection Method. Am J Eng IT. 2022 Feb 2;2:13-26. doi: 10.34104/ajeit.022.013026.
- Eisemann N, et al. Nationwide real-world implementation of AI for cancer detection in population-based mammography screening. Nat Med. 2025 Jan 7. doi: 10.1038/s41591-024-03408-6.
- Killock D. AI outperforms radiologists in mammographic screening. Nat Rev Clin Oncol. 2020 Jan 21;17(3):134. doi: 10.1038/s41571-020-0329-7.
- Kapoor N, Lacson R, Khorasani R. Workflow Applications of Artificial Intelligence in Radiology and an Overview of Available Tools. J Am Coll Radiol. 2020 Nov;17(11S):S5-S11. doi: 10.1016/j.jacr.2020.08.016.
- Hirsch L, et al. Predicting breast cancer with AI for individual risk-adjusted MRI screening and early detection. arXiv [Preprint]. 2023 Jan 1. doi: 10.48550/arXiv.2312.
- Kim S, et al. Deep learning-based computer-aided diagnosis in screening breast ultrasound to reduce false-positive diagnoses. Sci Rep. 2021 Jan 11;11:102. doi: 10.1038/s41598-020-79880-0.
- Shen Y, et al. Artificial intelligence system reduces false-positive findings in the interpretation of breast ultrasound exams. Nat Commun. 2021 Sep 24;12(1):5645. doi: 10.1038/s41467-021-26023-2.
- Dias R, Torkamani A. Artificial intelligence in clinical and genomic diagnostics. Genome Med. 2019 Nov 19;11(1):40. doi: 10.1186/s13073-019-0689-8.
- Dankwa‐Mullan I, Weeraratne D. Artificial Intelligence and Machine Learning Technologies in Cancer Care: Addressing Disparities, Bias, and Data Diversity. Cancer Discov. 2022 Jun 2;12(6):1312-1315. doi: 10.1158/2159-8290.CD-22-0373.
- Schork NJ. Artificial Intelligence and Personalized Medicine. In: Cancer Treatment and Research. Cham: Springer; 2019. p. 265-283. doi: 10.1007/978-3-030-16391-4_11.
- Bailey M. His Apple Watch warned of an irregular heart rate. Turns out he was having a heart attack. Global News. 2024 Jun [cited 2025 Feb 11]. Available from: https://globalnews.ca/news/10567186/apple-watch-notifys-man-having-heart-attack/
- Hall Z. Couple credits Apple Watch for detecting silent heart condition requiring medical intervention. 9to5Mac. 2024 Feb [cited 2025 Feb 11]. Available from: https://9to5mac.com/2024/02/12/couple-credits-apple-watch-for-detecting-silent-heart-condition-requiring-medical-intervention/
- Undiagnosed heart blockage detected thanks to Apple Watch. AppleInsider. 2023 Jan [cited 2025 Feb 11]. Available from: https://appleinsider.com/articles/23/01/16/undiagnosed-heart-blockage-detected-thanks-to-apple-watch
- Tran VT, Riveros C, Ravaud P. Patients’ views of wearable devices and AI in healthcare: findings from the ComPaRe e-cohort. npj Digit Med. 2019 Jun 14;2:53. doi: 10.1038/s41746-019-0132-y.
- Mohammadi FG, Shenavarmasouleh F, Arabnia HR. Applications of Machine Learning in Healthcare and Internet of Things (IoT): A Comprehensive Review. arXiv [Preprint]. 2022 Feb 6. doi: 10.48550/arxiv.2202.02868.
- Gruson D, Bernardini S, Dabla PK, Gouget B, Stanković S. Collaborative AI and Laboratory Medicine integration in precision cardiovascular medicine. Clin Chim Acta. 2020 Jun 4;510:160-166. doi: 10.1016/j.cca.2020.06.001.
- Lambert SI, et al. An integrative review on the acceptance of artificial intelligence among healthcare professionals in hospitals. npj Digit Med. 2023 Jun 10;6(1):98. doi: 10.1038/s41746-023-00852-5.
- Varnosfaderani SM, Forouzanfar M. The Role of AI in Hospitals and Clinics: Transforming Healthcare in the 21st Century. Bioengineering. 2024 Mar 29;11(4):337. doi: 10.3390/bioengineering11040337.

Research and Reviews: A Journal of Health Professions
| Volume | 15 |
| Issue | 03 |
| Received | 27/05/2025 |
| Accepted | 20/06/2025 |
| Published | 04/11/2025 |
| Publication Time | 161 Days |
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