A Research on Formulation and Evaluation of Clove Gel for Treatment of Scabies

Year : 2024 | Volume :11 | Issue : 03 | Page : 24-33
By
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Bhagyashri N. Patil,

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Bhupendra A. Patil,

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Bhagvati V. Patil,

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Atharv K. Patil,

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Amruta N. Patil,

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Sunil P. Pawar,

  1. Research Scholar, Department of Pharmaceutics, Poojya Sane Guruji Vidya Prasarak Mandal’s College of Pharmacy, Shahada, Maharashtra, India
  2. Research Scholar, Department of Pharmaceutics, Poojya Sane Guruji Vidya Prasarak Mandal’s College of Pharmacy, Shahada, Maharashtra, India
  3. Research Scholar, Department of Pharmaceutics, Poojya Sane Guruji Vidya Prasarak Mandal’s College of Pharmacy, Shahada, Maharashtra, India
  4. Research Scholar, Department of Pharmaceutics, Poojya Sane Guruji Vidya Prasarak Mandal’s College of Pharmacy, Shahada, Maharashtra, India
  5. Associate Professor, Department of Pharmaceutical Chemistry, Poojya Sane Guruji Vidya Prasarak Mandal’s College of Pharmacy, Shahada, Maharashtra, India
  6. Principal, Poojya Sane Guruji Vidya Prasarak Mandal’s College of Pharmacy, Maharashtra, India

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Scabies remains a pervasive global health issue, with a need for more effective topical treatments. This research focuses on the formulation and evaluation of a clove oil-based gel containing eugenol, the primary bioactive component, for the treatment of scabies. Eugenol’s well-documented antimicrobial, anti-inflammatory, and ant parasitic activities make it an ideal candidate for targeting Sarcoptes scabiei, the mite responsible for scabies. The formulation was prepared by incorporating clove oil and eugenol into a gel base with suitable excipients such as gelling agents, preservatives, and stabilizers. Key parameters like physical appearance, pH, homogeneity, spread ability, and extrudability were systematically evaluated to optimize the gel’s therapeutic properties and user acceptability. Eugenol, as the active pharmaceutical ingredient, was used to ensure targeted therapeutic efficacy, while excipients were selected to enhance the gel’s stability and application.

Keywords: Scabies, eugenol, clove, scabies treatment, sarcoptes scabies

[This article belongs to Research & Reviews: A Journal of Drug Formulation, Development and Production (rrjodfdp)]

How to cite this article:
Bhagyashri N. Patil, Bhupendra A. Patil, Bhagvati V. Patil, Atharv K. Patil, Amruta N. Patil, Sunil P. Pawar. A Research on Formulation and Evaluation of Clove Gel for Treatment of Scabies. Research & Reviews: A Journal of Drug Formulation, Development and Production. 2024; 11(03):24-33.
How to cite this URL:
Bhagyashri N. Patil, Bhupendra A. Patil, Bhagvati V. Patil, Atharv K. Patil, Amruta N. Patil, Sunil P. Pawar. A Research on Formulation and Evaluation of Clove Gel for Treatment of Scabies. Research & Reviews: A Journal of Drug Formulation, Development and Production. 2024; 11(03):24-33. Available from: https://journals.stmjournals.com/rrjodfdp/article=2024/view=0

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Regular Issue Subscription Original Research
Volume 11
Issue 03
Received 01/09/2024
Accepted 10/10/2024
Published 28/10/2024
157

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