Green Synthesis of Copper Nano Particle for the Treatment of Neurodegenerative Disease

Year : 2024 | Volume :14 | Issue : 01 | Page : 13-24
By

    Gauri Chaturvedi

  1. PG Student, Department of Biotechnology, Amity University, Noida, Uttar Pradesh, India

Abstract

The study of ecologically friendly CuNP synthesis is a growing area with potential applications in biomedical research and environmental remediation, as well as sustainable nanotechnology. Generally, reducing and stabilizing agents such as microbes, plant extracts, or other natural sources are used. The green synthesis methodology guarantees the production of nanoparticles with desired characteristics for biomedical applications while simultaneously mitigating the environmental effect that comes with conventional chemical processes. CuNPs possess natural anti-inflammatory and antioxidant properties, which are crucial for mitigating neuroinflammation and oxidative stress, both prominent symptoms associated with neurodegenerative conditions. Moreover, CuNPs’ small size and large surface area enable targeted distribution to the central nervous system by facilitating their passage through the blood-brain barrier. Once inside the brain, CuNPs can interact with tau protein aggregates and amyloid-beta plaques, two important cellular elements involved in neurodegeneration, to potentially halt the progression of the illness and have neuroprotective benefits. The potential of environmentally friendly synthesized copper nanoparticles (CuNPs) as an innovative therapeutic approach for the treatment of neurodegenerative diseases is promising. Further research is necessary to determine the precise processes by which these nanoparticles function, enhance their efficacy by optimizing their characteristics, and evaluate their safety in preclinical and clinical settings. There is hope that the development of CuNP-based treatments will help alleviate the rising prevalence of neurodegenerative diseases and improve the quality of life for those affected. It is imperative to investigate the pharmacology and biological distribution of copper nanoparticles throughout the body, in addition to the mechanisms that underlie their therapeutic potential in neurodegenerative illnesses. Gaining knowledge on the absorption, distribution, metabolization, and excretion of these nanoparticles will help to understand their safety profile and possible adverse effects.

Keywords: Copper nanoparticles (CuNPs), green synthesis, neurodegenerative diseases, biomedical applications, blood-brain barrier

[This article belongs to Research & Reviews : A Journal of Biotechnology(rrjobt)]

How to cite this article: Gauri Chaturvedi , Green Synthesis of Copper Nano Particle for the Treatment of Neurodegenerative Disease rrjobt 2024; 14:13-24
How to cite this URL: Gauri Chaturvedi , Green Synthesis of Copper Nano Particle for the Treatment of Neurodegenerative Disease rrjobt 2024 {cited 2024 Apr 13};14:13-24. Available from: https://journals.stmjournals.com/rrjobt/article=2024/view=143361


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Regular Issue Subscription Review Article
Volume 14
Issue 01
Received March 2, 2024
Accepted March 27, 2024
Published April 13, 2024
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