Exploring Phytomedicine: Innovations, Efficacy and Future Directions

Notice

This is an unedited manuscript accepted for publication and provided as an Article in Press for early access at the author’s request. The article will undergo copyediting, typesetting, and galley proof review before final publication. Please be aware that errors may be identified during production that could affect the content. All legal disclaimers of the journal apply.

Year : 2025 | Volume : 14 | Issue : 02 | Page : 32 50
    By

    Mohd. Wasiullah,

  • Piyush Yadav,

  • Satish Kumar Yadav,

  • Rehan Ahmed Khan,

  1. Principal, Department of Pharmacy, Prasad Institute of Technology, Jaunpur- 222001, Uttar Pradesh, India
  2. Academic Head, Department of Pharmacy, Prasad Institute of Technology, Jaunpur- 222001, ,
  3. Associate Professor, Department of Pharmacy, Prasad Institute of Technology, Jaunpur- 222001, Uttar Pradesh, India
  4. Associate Professor, Department of Pharmacy, Prasad Institute of Technology, Jaunpur- 222001, Uttar Pradesh, India

Abstract

The use of plant-derived substances for therapeutic purposes has long been a cornerstone of traditional medicine systems worldwide. With increasing interest in natural remedies, the field of phytomedicine is experiencing a revival, marked by innovations in research, formulation, and application. This review article explores recent advancements in phytomedicine, highlighting novel extraction technologies, and the efficacy of plant-based treatments in clinical settings. The review also addresses the challenges faced in phytomedicine research, including issues related to standardization, safety, and regulatory hurdles. Furthermore, we provide a comprehensive overview of current trends and future directions, emphasizing the need for interdisciplinary approaches to integrate phytomedicine into modern healthcare practices. By synthesizing recent findings and identifying gaps in knowledge, this article aims to offer valuable insights and guidance for researchers, practitioners, and policy makers working towards the advancement of phytomedicine.

Keywords: Phytomedicine, phytochemicals, herbal medicines, medicinal plant, nutraceuticals.

[This article belongs to Research & Reviews : Journal of Botany ]

How to cite this article:
Mohd. Wasiullah, Piyush Yadav, Satish Kumar Yadav, Rehan Ahmed Khan. Exploring Phytomedicine: Innovations, Efficacy and Future Directions. Research & Reviews : Journal of Botany. 2025; 14(02):32-50.
How to cite this URL:
Mohd. Wasiullah, Piyush Yadav, Satish Kumar Yadav, Rehan Ahmed Khan. Exploring Phytomedicine: Innovations, Efficacy and Future Directions. Research & Reviews : Journal of Botany. 2025; 14(02):32-50. Available from: https://journals.stmjournals.com/rrjob/article=2025/view=203867


References

  1. Pandey Mukeshwar, Mousumi, Gupta Shobit and K.C.Surender (2011). Phytomedicine: An ancient approach turning into future potential source of therapeutics. Journal of Pharmacognosy and Phytotherapy Vol. 3(3) pp. 27-37.
  2. Malone, M.H., 1977. Pharmacological approaches to natural product screening and evaluation. In New Natural Products and Plant Drugs with Pharmacological, Biological or Therapeutical Activity: Proceedings of the First International Congress on Medicinal Plant Research, Section A, held at the University of Munich, Germany, September 6–10, 1976(pp. 23-53). Berlin, Heidelberg: Springer Berlin Heidelberg.
  3. Leslie TN. Plant based drugs and medicines. Raintree nutrition. 2000;4(1):340-50.
  4. Farnsworth, N.R., Bingel, A.S., Problems and prospects of discovery new drugs from higher plants by pharmacological screening. In: Wagner, H., Wolff, P. (Eds.) New Natural Products and Plant Drugs with Pharmacological, Biological and therapeutical activity. Springer Verlag, Berlin, pp. 1-22.
  5. Hasan, S. Zeeshan, Vedant Misra Vedant Misra, Swati Singh Swati Singh, Garvita Arora Garvita Arora, Sunita Sharma Sunita Sharma, and Sarika Sharma Sarika Sharma. “Current status of herbal drugs and their future perspectives.” (2009): 12-17.
  6. Vickers A, Zollman C. Corrections-ABC of complementary medicine: Herbal medicine. BMJ-British Medical Journal-International Edition. 1999;319(7222):1422-1422.
  7. Moteriya, P., Satasiya, R., Chanda, S., 2015. Screening of phytochemical constituents in some ornamental flowers of Saurashtra J. Pharmacog. Phytochem. 3 (5), 112_120.
  8. Aggarwal, B. B., & Harikumar, K. B. (2009). Potential therapeutic effects of curcumin, the anti-inflammatory agent, against cancer. Anticancer Research, 29(9), 3635-3648.
  9. Hewlings, S. J., & Kalman, D. S. (2017). Curcumin: A review of its effects on human health. Foods, 6(10), 92.
  10. Reay, J. L., Kennedy, D. O., & Scholey, A. B. (2006). Single doses of Panax ginseng (G115) reduce blood glucose levels and improve cognitive performance during sustained mental activity. Journal of Psychopharmacology, 20(6), 771-781
  11. Attele, A. S., Wu, J. A., & Yuan, C. S. (1999). Ginseng pharmacology: Multiple constituents and multiple actions. Biochemical Pharmacology, 58(11), 1685-1693.
  12. Abenavoli, L., et al. (2018). Milk thistle (Silybum marianum): A concise overview on its chemistry, pharmacological, and nutraceutical uses in liver diseases. Current Bioactive Compounds, 14(4), 388-400.
  13. Loguercio, C., & Festi, D. (2011). Silybin and the liver: From basic research to clinical practice. World Journal of Gastroenterology, 17(18), 2288.
  14. Barrett, B. (2003). Medicinal properties of Echinacea: A critical review. Phytomedicine, 10(1), 66-86. Snitz, E., et al. (2009). Ginkgo biloba for preventing cognitive decline in older adults. JAMA, 302(24), 2663-2670.Vogler, B. K., & Ernst, E. (1999). Aloe vera: A systematic review of its clinical effectiveness. British Journal of General Practice, 49(447), 823-828.
  15. Banerjee, S. K., & Maulik, S. K. (2002). Effect of garlic on cardiovascular disorders: A review. Nutrition Journal, 1(1), 1-14.
  16. Singh, N., Bhalla, M., de Jager, P., & Gilca, M. (2011). An overview on ashwagandha: A Rasayana (rejuvenator) of Ayurveda. African Journal of Traditional, Complementary, and Alternative Medicines, 8(5S).
  17. Grigoleit, G., & Grigoleit, P. (2005). Peppermint oil in irritable bowel syndrome. Phytomedicine, 12(8), 601-606.
  18. Linde, K., & Mulrow, C. D. (2000). St John’s wort for depression. Cochrane Database of Systematic Reviews, (2).
  19. Wang, H., & Prosky, L. (1997). Effects of green tea and other tea polyphenols on cancer prevention and treatment. Journal of the American College of Nutrition, 16(5), 373-374.
  20. Borrelli, F., Capasso, R., & Izzo, A. A. (2004). The advantages of being a ginger: Multiple effects of Zingiber officinale. British Journal of Pharmacology, 141(8), 1391-
  21. Bent, S., et al. (2006). Saw palmetto for benign prostatic hyperplasia. The New England Journal of Medicine, 354(6), 557-566.
  22. Bent, S., et al. (2006). Valerian root for anxiety disorders. The American Journal of Medicine, 119(12), 1001.e1-1001.e8.
  23. Howell, A. B. (2002). Cranberry proanthocyanidins and the maintenance of urinary tract health. Critical Reviews in Food Science and Nutrition, 42(3), 273-278
  24. Fiore, , et al. (2005). The potential of licorice in medicinal and cosmetic applications.Phytotherapy Research, 19(10), 863-868.
  25. Pittler, M. H., & Ernst, E. (2002). Hawthorn extract for treating chronic heart failure: Meta-analysis of randomized trials. The American Journal of Medicine, 113(6), 462-468.
  26. Kaur Navneet et al.(2019). Phytomedicine: history, scope and future prospects. https://doi.org/10.1515/9783110563337-006.
  27. Calixto J.B.(2000). Efficacy, safety, quality control, marketing and regulatory guidelines for herbal medicine (phytotherapeutic agents). Brazilian journal of medical and biological research 33: 179-189.
  28. Bhusnure et al.(2019). Phytopharmaceuticals: An emerging platform for innovation and development of new drugs from botanicals. Journal of Drug Delivery & Therapeutics. 2019; 9(3-s):1046-1057.
Regular Issue Subscription Review Article
Volume 14
Issue 02
Received 14/12/2024
Accepted 07/01/2025
Published 10/01/2025
Publication Time 27 Days
173

Login


My IP

PlumX Metrics