A Brief Review on Herbal Excipients

Year : 2025 | Volume : 12 | Issue : 02 | Page : 5 14
    By

    Neha S. Patil,

  • Divakar R. Patil,

  • Akash S. Jain,

  • Azam Z. Shaikh,

  • Sameer R. Shaikh,

  • Sunil P. Pawar,

  1. Student, Department of Pharmaceutics, P.S.G.V.P. Mandal’s College of Pharmacy, Shahada, Maharashtra, India
  2. Assistant Professor, Department of Pharmaceutics, P.S.G.V.P. Mandal’s College of Pharmacy, Shahada, Maharashtra, India
  3. Assistant Professor, Department of Quality Assurance, P.S.G.V.P. Mandal’s College of Pharmacy, Shahada, Maharashtra, India
  4. Assistant Professor, Department of Pharmaceutics, P.S.G.V.P. Mandal’s College of Pharmacy, Shahada, Maharashtra, India
  5. Assistant Professor, Department of Pharmaceutics, P.S.G.V.P. Mandal’s College of Pharmacy, Shahada, Maharashtra, India
  6. Principal, P.S.G.V.P. Mandal’s College of pharmacy, Shahada, Maharashtra, India

Abstract

Natural or herbal excipients are significantly more advantageous than their synthetic equivalents because they are readily available, non-toxic, and less expensive. The pharmaceutical industries are becoming more interested in using these herbal excipients – mainly polymers of natural origin – in formulation development because of growing knowledge of them. The purpose of this study is to provide light on the possibility of using natural excipients, which are biocompatible and able to provide additional nutrition to the produced dosage form, as a diluent, binder, disintegrant, and lubricant in various formulation types. An overview of natural excipients used in both novel and conventional drug delivery methods is provided in this article. Medical science is developing at an extremely rapid rate these days. Different kinds of formulations are found to be effective for treating certain diseases. Given that a dosage form is made up of an active pharmaceutical ingredient (API) and an excipient, it follows that an excipient is required for the formulation of all pharmacological dosage forms. Natural excipients derived from plant sources, such as gums, mucilages, starches, and cellulose have demonstrated promising functional properties, including swelling, gel formation, and mucoadhesion, which enhance drug delivery and therapeutic efficacy. Their biodegradability and minimal side effects make them suitable for long-term use and safer for patients with sensitivity to synthetic additives. Moreover, the eco-friendly nature of herbal excipients aligns with the increasing global demand for sustainable pharmaceutical practices. Current research also focuses on modifying natural polymers to improve their physicochemical characteristics, enabling their application in advanced drug delivery systems like nanoparticles, transdermal patches, and controlled-release formulations for enhanced patient compliance.

Keywords: Natural, Herbal, Nanoparticles, Polymer, Pharmaceuticals , Excipients

[This article belongs to Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy ]

How to cite this article:
Neha S. Patil, Divakar R. Patil, Akash S. Jain, Azam Z. Shaikh, Sameer R. Shaikh, Sunil P. Pawar. A Brief Review on Herbal Excipients. Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy. 2025; 12(02):5-14.
How to cite this URL:
Neha S. Patil, Divakar R. Patil, Akash S. Jain, Azam Z. Shaikh, Sameer R. Shaikh, Sunil P. Pawar. A Brief Review on Herbal Excipients. Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy. 2025; 12(02):5-14. Available from: https://journals.stmjournals.com/rrjoasyn/article=2025/view=213354


References

  1. Li M, Luo Q, Tao Y, Sun X, Liu C. Pharmacotherapies for drug-induced liver injury: A current literature review. Frontiers in pharmacology. 2022 Jan 5;12:806249.
  2. Bahadur S, Sahu UK, Sahu D, Sahu G, Roy A. Review on natural gums and mucilage and their application as excipient. J Appl Pharm Res. 2017 Dec 24;5(4):13–21.
  3. Shirwaikar A, Shirwaikar A, Prabu SL, Kumar GA. Herbal excipients in novel drug delivery systems. Indian J Pharm Sci. 2008 Jul;70(4):415.
  4. Pal RS, Pal Y, Wal A, Wal P. Current review on plant based pharmaceutical excipients. Open Med J. 2019 Feb 19;6(1).
  5. Singh P, Mahmood T, Shameem A, Bagga P, Ahmad N. A review on Herbal Excipients and their pharmaceutical applications. Scholars Acad J Pharm. 2016;5(3):53–7.
  6. Poonam V, Sagar G, Abhishek K, Yuvraj S. Remarkable contribution of natural excipients in finished pharmaceutical products (FPPs). Int J Pharm Sci Res. 2018;52(1):7–14.
  7. Jain A, Radiya P, Wadekar R, Limaye S, Pawar C. Natural excipients-an alternative to synthetic excipients: A comprehensive review. Int J Pharm Med Res. 2014 Aug 25;2(4):123–7.
  8. Shinde SA, Sapkal SB, Shrikhande VN. Herbal excipients in novel drug delivery systems. Asian J Pharm Res. 2017;7(2):111–7.
  9. Selvadurai S, Divya S, Geetha A, Rohini K, Anbazhagan S. Herbal Excipients-Significance of Substances of Natural Origin as Excipients.
  10. Shinde VM, Bodas Yadav KS. Herbal Drug Technology, 1st edition, Nirali 2019. IJPRIF. 2020;13(03):242–252,
  11. Jani GK, Shah DP, Prajapati VD, Jain VC. Gums and mucilages: versatile excipients for pharmaceutical formulations. Asian J Pharm Sci. 2009;4(5):309–23.
  12. Gupta N, Gupta A. A review on herbal excipients. Int J Indigenous Herbs and Drugs. 2021 Feb 15:05–8.
  13. Kumar T, Gupta SK, Prajapati MK, Tripathi D. Natural excipients: A review. Asian J Pharm Life Sci. 2012;2231:4423.
  14. Egbuna C, Mishra AP, Goyal MR, editors. Preparation of phytopharmaceuticals for the management of disorders: The development of nutraceuticals and traditional medicine. Academic Press; 2020 Nov 3.
  15. Patil SV, Ghatage SL, Navale SS, Mujawar NK. Natural binders in tablet formulation. Int J PharmTech Res. 2014;6(3):1070–3.
  16. Singh P, Mahmood T, Shameem A, Bagga P, Ahmad N. A review on Herbal Excipients and their pharmaceutical applications. Scholars Acad J Pharm. 2016;5(3):53–7.
  17. Chengaiah B, Rao KM, Kumar KM, Alagusundaram M, Chetty CM. Medicinal importance of natural dyes-a review. Int J PharmTech Res. 2010 Jan;2(1):144–54.
  18. Patil A, Bhide S, Bookwala M, Soneta B, Shankar V, Almotairy A, et al. Stability of organoleptic agents in pharmaceuticals and cosmetics. AAPS pharmscitech. 2018 Jan;19:36–47.
  19. Mam NM, Bias S, Manasi M. Review on herbal excipients. Res J Pharm Phytochem. 2023;15(2):118–24.
  20. Chavhan SA, Shinde SK, Sapkal SB, Shrikhande VN. Herbal excipients in novel drug delivery systems. Int J Res Develop Pharm Life Sci. 2017 May 15;6(3):2597–605.
  21. Alwossabi A, Elamin ES, Ahmed EM, Abdelrahman M. Natural excipients applications in conventional pharmaceutical formulations-Part I. Med Aromat Plants (LosAngeles). 2021;10:397.
  22. Tønnesen HH, Karlsen J. Alginate in drug delivery systems. Drug Develop Indust Pharm. 2002 Jan 1;28(6):621–30
  23. Chaturvedi S, Kulshrestha S, Bhardwaj K, Jangir R. A review on properties and applications of xanthan gum. Microbial Polymers: Applications and Ecological Perspectives. 2021:87–107.
  24. Jain A, Radiya P, Wadekar R, Limaye S, Pawar C. Natural excipients-an alternative to synthetic excipients: a comprehensive review. Int J Pharm Med Res. 2014 Aug 25;2(4):123–7.
  25. Gupta N, Gupta A. A review on herbal excipients. Int J Indigenous Herbs and Drugs. 2021 Feb 15:05–8.
  26. Kumar S, Gupta SK. Natural polymers, gums and mucilages as excipients in drug delivery. Polim. Med. 2012 Jan 1;42(3–4):191–7.
  27. Ogaji IJ, Nep EI, Audu-Peter JD. Advances in natural polymers as pharmaceutical excipients. Pharmaceutica Analytica Acta. 2012 Jan 18;3(1):1–6.
  28. Bhaskar DA, Uttam KJ, Mahendrasingh A, Jayram CM, Bhanudas SR. Plant exudates and mucilage as pharmaceutical excipients. J Adv Pharm Educ Res. 2013;3(4):387–402.
Regular Issue Subscription Review Article
Volume 12
Issue 02
Received 09/04/2025
Accepted 12/05/2025
Published 15/05/2025
Publication Time 36 Days
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