Effect of Snehpana (Lipid Based Drug Delivery System) with Shatpala Ghrit in Non-Alcholic Fatty Liver Diseases

Year : 2024 | Volume : 12 | Issue : 01 | Page : 1-11
    By

    Anshul,

  • Ashish Mehta,

  1. Assistant Professor, Department of Panchkarma, Gaur Brahman Ayurvedic College, Brahmanwas, Rohtak, Haryana, India
  2. Professor and HOD, Department of Panchkarma, Shri Krishna AYUSH University, Haryana, India

Abstract

Among all the Drug Delivery Systems, Snehpana (~Lipid Based Drug Delivery System) is being widely used because this facilitates uniform distribution and absorption of fat and water-soluble chemical constituents. Due to their effective size-dependent properties and challenges related to the solubility and bioavailability of water-soluble drugs, this system holds a significant advantage. Numerous studies have highlighted the potential of lipid-based formulations in managing chronic and life-threatening diseases. Shatpala ghrit (SG) shows promise for use in clinical applications. Previously no clinical and animal studies data report evidence showcased till date on SG. SG references from ancient ayurvedic writings, such as Charak Samhita, Sushrut Samhita, Astang Hridyam, among others, have been gathered. The many techniques of preparing same medication are examined critically. Probable mode of action of SG in non-alcoholic fatty liver understood after critical analysis of various studies (clinical and experimental). Ketone formation occurs during Snehpana, which inhibits de novo lipogenesis and promotes fatty acid oxidation, resulting in weight loss and decreased hepatic fat content. Evidence indicates that ketones play a protective role in the pathogenesis of non-alcoholic fatty liver disease (NAFLD). It can be concluded that Snehpana with Shatpala ghrit can be beneficial in reversing the stages of NAFLD.

Keywords: Shatpala ghrita, Snehpana, Lipid Based Drug Delivery System, NAFLD

[This article belongs to Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy ]

How to cite this article:
Anshul, Ashish Mehta. Effect of Snehpana (Lipid Based Drug Delivery System) with Shatpala Ghrit in Non-Alcholic Fatty Liver Diseases. Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy. 2025; 12(01):1-11.
How to cite this URL:
Anshul, Ashish Mehta. Effect of Snehpana (Lipid Based Drug Delivery System) with Shatpala Ghrit in Non-Alcholic Fatty Liver Diseases. Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy. 2025; 12(01):1-11. Available from: https://journals.stmjournals.com/rrjoasyn/article=2025/view=194418



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Regular Issue Subscription Original Research
Volume 12
Issue 01
Received 28/11/2024
Accepted 24/12/2024
Published 16/01/2025
Publication Time 49 Days
Total Visits: 72


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