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Mohd. Wasiullah,
Piyush Yadav,
Ajay Kumar Yadav,
- Principle, Department of Pharmacy, Prasad Institute of Technology,Jaunpur (222001), Uttar Pradesh, India
- Academic Head, Department of Pharmacy, Prasad Institute Technology, Jaunpur (222001), Uttar Pradesh, India
- Scholor, Department of Pharmacy, Prasad Institute of Technology, Jaunpur (222001), Uttar Pradesh, India
Abstract document.addEventListener(‘DOMContentLoaded’,function(){frmFrontForm.scrollToID(‘frm_container_abs_130898’);});Edit Abstract & Keyword
This review provides an in-depth exploration of the evolution of ointment formulations, particularly in light of the increasing prevalence of fungal infections and the growing demand for effective antifungal treatments. Traditional ointment formulations, while useful, often face significant challenges such as inadequate penetration into the skin, poor bioavailability, and undesirable textures that limit their efficacy. As a result, there has been a shift towards more advanced, innovative formulations that aim to address these shortcomings. Nanomedicine and nanotechnology have played a pivotal role in this transition, leading to the development of novel drug delivery systems such as nanoemulsions, liposomes, solid lipid nanoparticles, and nanostructured lipid carriers. These systems enhance the stability, bioavailability, and targeted delivery of antifungal agents, thereby improving treatment outcomes.
The review also highlights the use of both natural and synthetic polymers in the development of wound and burn dressings, underscoring their biocompatibility, biodegradability, and potential for tissue regeneration. Hydrogels, in particular, are noted for their promising applications in transdermal drug delivery systems due to their ability to provide sustained release and enhance skin permeability. Furthermore, the review discusses the importance of safety and efficacy evaluations through various methods, including in vitro and in vivo studies, clinical trials, and regulatory standards like Good Manufacturing Practices and pharmacovigilance, ensuring that these formulations meet safety and performance criteria.
Keywords: Na noemulsion, Solid Lipid Nanoparticles, Hydrogels, Invivo, Liposomes
[This article belongs to Nano Trends – A Journal of Nano Technology & Its Applications (nts)]
Mohd. Wasiullah, Piyush Yadav, Ajay Kumar Yadav. Advanced Ointment Formulation: An Insightful Review of Innovation and Efficacy. Nano Trends – A Journal of Nano Technology & Its Applications. 2025; 27(01):-.
Mohd. Wasiullah, Piyush Yadav, Ajay Kumar Yadav. Advanced Ointment Formulation: An Insightful Review of Innovation and Efficacy. Nano Trends – A Journal of Nano Technology & Its Applications. 2025; 27(01):-. Available from: https://journals.stmjournals.com/nts/article=2025/view=0
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