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Shivanand Yadav,
Mohd. Wasiullah,
Piyush Yadav,
Sumit Yadav,
- Assistant Professor, Department of Pharmacy, Prasad Institute of Technology, Jaunpur (222001), Uttar Pradesh, India
- Principle, Department of Pharmacy, Prasad Institute Technology, Jaunpur (222001), Uttar Pradesh, India
- Academic Head, Department of Pharmacy, Prasad Institute of Technology, Jaunpur (222001), Uttar Pradesh, India
- Scholor, Department of Pharmacy, Prasad Institute of Technology, Jaunpur (222001), Uttar Pradesh, India
Abstract document.addEventListener(‘DOMContentLoaded’,function(){frmFrontForm.scrollToID(‘frm_container_abs_130873’);});Edit Abstract & Keyword
Nanotechnology has become a groundbreaking strategy in cancer therapy, especially in drug delivery systems, offering improved treatment effectiveness while minimizing the adverse effects associated with traditional methods. This review presents an in-depth analysis of recent progress in nanotechnology for cancer drug delivery, emphasizing the design, mechanisms, and practical applications of nanoparticle-based systems. Nanoparticles, such as liposomes, dendrimers, and gold nanoparticles, offer unique advantages, including improved drug solubility, targeted delivery to tumor cells, and controlled release of therapeutic agents. These systems can be designed to target cancerous tissues specifically, reducing harm to healthy cells and substantially enhancing the therapeutic index. The review also highlights various strategies for achieving targeted drug delivery, such as passive targeting via the enhanced permeability and retention (EPR) effect, and active targeting using surface modifications like antibodies or ligands that bind specifically to cancer cell receptors. Moreover, incorporating imaging functionalities into nanoparticles enables real-time tracking of treatment progress and evaluation of tumor response. The potential of multifunctional nanoparticles, which can combine drug delivery, imaging, and treatment monitoring, is also explored. Despite the promising benefits, challenges related to nanoparticle stability, scaling up production, and regulatory hurdles remain. This review concludes by discussing future directions for research and development in cancer nanomedicine, emphasizing the need for personalized treatment strategies and the continued evolution of nanotechnology to improve patient outcomes.
Keywords: Nanotechnology, antitumor drug delivery, nanoparticles, controlled release, personalized medicine .
[This article belongs to Nano Trends – A Journal of Nano Technology & Its Applications (nts)]
Shivanand Yadav, Mohd. Wasiullah, Piyush Yadav, Sumit Yadav. A Comprehensive Review: Emerging Nanotechnology in Cancer Drug Delivery. Nano Trends – A Journal of Nano Technology & Its Applications. 2025; 27(01):-.
Shivanand Yadav, Mohd. Wasiullah, Piyush Yadav, Sumit Yadav. A Comprehensive Review: Emerging Nanotechnology in Cancer Drug Delivery. Nano Trends – A Journal of Nano Technology & Its Applications. 2025; 27(01):-. Available from: https://journals.stmjournals.com/nts/article=2025/view=0
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Nano Trends – A Journal of Nano Technology & Its Applications
Volume | 27 |
Issue | 01 |
Received | 14/12/2024 |
Accepted | 30/12/2024 |
Published | 03/01/2025 |