Noor M. Hasnawi,
Zahraa Hussein Abdulateef Ali,
- Lecturer, Department of Forensic Techniques, Al-Furat Al-Awsat Technical University, Najaf, Najaf Governorate, , Iraq
- Assistant Lecturer, Department of Dental Industry, Al-Furat Al-Awsat Technical University, Najaf, Najaf Governorate, , Iraq
Abstract
This revision considers the belongings of Tartrazine and black seed nanoparticles on body mass and cardiac histology in male albino mice. Group of male mice were separated into 4 clusters: a regulator cluster getting physiological saline, other cluster preserved with Tartrazine (20 mg/kg), another cluster getting equally Tartrazine with N. sativa nanoparticles (100 mg/kg), while last cluster preserved solely besides to N. sativa nanoparticles (100 mg/kg). The assumptions confirmed an important escalation in body mass in the Tartrazine cluster associated with the regulator, portentous that Tartrazine could inspire metabolic lanes. Co-administration of N. sativa nanoparticles with Tartrazine occasioned in a straight more proliferation in body mass, representing a potential synergistic consequence. However, N. sativa nanoparticles on their own showed no notable effect on body weight. Histological analysis of cardiac tissues revealed no structural alterations across all treatment groups, suggesting that the administered doses did not cause cardiotoxic effects. These fallouts propose that although Tartrazine significantly disturbs body mass, it does not alter cardiac histology below the disorders calculated., The revision targeted to reveal the bearing of lately synthesized nanoparticles on hemolytic anemia finished the behind specific intentions: Synthesis of iron nanoparticles., Planning of N. sativa quotation nanoparticles at capricious meditations., Analysis of the possessions of N. sativa seed nanoparticles on minor intestine healthiness.
Keywords: Hemolytic, anemia, cardiac, Investigation, nanoparticles
[This article belongs to Nano Trends – A Journal of Nano Technology & Its Applications ]
Noor M. Hasnawi, Zahraa Hussein Abdulateef Ali. Histological Effects of Nano-Synthesized Particles of Nagilla Sativa Seeds Extract on Digestive System of Male Albino Mice. Nano Trends – A Journal of Nano Technology & Its Applications. 2025; 27(01):1-6.
Noor M. Hasnawi, Zahraa Hussein Abdulateef Ali. Histological Effects of Nano-Synthesized Particles of Nagilla Sativa Seeds Extract on Digestive System of Male Albino Mice. Nano Trends – A Journal of Nano Technology & Its Applications. 2025; 27(01):1-6. Available from: https://journals.stmjournals.com/nts/article=2025/view=187463
Browse Figures
References
- Kumar R, DuMond JF, Khan SH, Thompson EB, He Y, Burg MB, et al. NFAT5, which protects against hypertonicity, is activated by that stress via structuring of its intrinsically disordered domain. Proc Natl Acad Sci USA. 2020;117(33):20292–20297. doi: 10.1073/pnas.1911680117.
- Essawy A, Matar S, Mohamed N, Abdel-Wahab W, Abdou H. Ginkgo biloba extract protects against tartrazine-induced testicular toxicity in rats: Involvement of antioxidant, anti-inflammatory, and anti-apoptotic mechanisms. Environ Sci Pollut Res Int. 2024;31(10):15065–15077. doi: 10.1007/s11356-024-32047-0.
- Al Asoom L. Is Nigella sativa an effective bodyweight lowering agent and a mitigator of obesity risk? A literature review. Vasc Health Risk Manag. 2022;18:495–505. doi: 10.2147/VHRM.S373702.
- Kabir Y, Akasaka-Hashimoto Y, Kubota K, Komai M. Volatile compounds of black cumin (Nigella sativa) seeds cultivated in Bangladesh and India. Heliyon. 2020;6(10):e05343. doi: 10.1016/j.
- Al Ardhil JAM, Aziz Alshemkhi MA. The histological structure of thyroid gland and the relationship between the hyperthyroidism and total protein, albumin, globulin, liver enzymes and some minerals deficiency. Int J Pharmtech Res. 2016;9(8):189–196.
- Sensoy I. A review on the food digestion in the digestive tract and the used in vitro models. Curr Res Food Sci. 2021;4:308–319. doi: 10.1016/j.crfs.2021.04.004.
- Rawan Hasan Abdul Aal, Siham Jasem Alkaabi. Inhibition activity of silver nanoparticles (AgNPs) biosynthesized by Ziziphus spina-christi leaf extract against local pathogenic bacterial isolates. Al-Harf Journal. 2024;22.
- Gieryńska M, Szulc-Dąbrowska L, Struzik J, Mielcarska MB, Gregorczyk-Zboroch KP. Integrity of the intestinal barrier: The involvement of epithelial cells and microbiota—a mutual relationship. Animals. 2022;12(2):145.
- Kastl Jr AJ, Terry NA, Wu GD, Albenberg LG. The structure and function of the human small intestinal microbiota: Current understanding and future directions. Cell Mol Gastroenterol Hepatol. 2020;9(1):33–45. doi: 10.1016/j.jcmgh.2019.07.006.
- Bernal A, Zafra MA, Simón MJ, Mahía J. Sodium homeostasis, a balance necessary for life. Nutrients. 2023;15(2):395. doi: 10.3390/nu15020395.
- Madhavan Unny N, Zarina A, Beena V. Fluid and Electrolyte Balance. In: Textbook of Veterinary Physiology. Singapore: Springer Nature Singapore; 2023. pp. 193–211.
- Mushattat SJ, Alaridi JA. Effect addition of the extract Nigella sativa on the histological and physiological changes of the domestic chicken experimental infected with Eimeria maxima. J Pharm Sci Res. 2018;10(8):1934–1938.
- Bankir L, Crambert G, Vargas-Poussou R. The SLC6A18 transporter is most likely a na-dependent glycine/urea antiporter responsible for urea secretion in the proximal straight tubule: Influence of this urea secretion on glomerular filtration rate. Nephron. 2024:1–27. doi: 10.1159/000539602.
- Abbood D, Mohammed Z, عنوز دصباح عباس. Silver biosynthesis, characterization, antioxidant, and antihemolysis activity of nanoparticles (AgNPs) produced using Cynophyta alga extract (Spirulina platensis). Al-Harf Journal. 2023;19.
- Amchova P, Siska F, Ruda-Kucerova J. Safety of tartrazine in the food industry and potential protective factors. Heliyon. 2024;10(18):e38111. doi: 10.1016/j.heliyon.2024.e38111
- Ravichandran G, Lakshmanan DK, Arunachalam A, Thilagar S. Food obesogens as emerging metabolic disruptors; A toxicological insight. J Steroid Biochem Mol Biol. 2022;217:106042. doi: 10.1016/j.jsbmb.2021.106042.
- Ethaeb AM, Al-Shaeli SJJ, Ahmed TH. Histopathological and hormonal evaluation of interaction effects of ethidium bromide, Nigella sativa, and silver nanoparticle on male rat fertility. Res J Pharm Technol. 2021;14(6):3184–3190. doi: 10.52711/0974-360X.2021.00555.
- Liu H, Dong X, Tan B, Du T, Zhang S, Yang Y, et al. Effects of fish meal replacement by low‐gossypol cottonseed meal on growth performance, digestive enzyme activity, intestine histology and inflammatory gene expression of silver sillago (Sillago sihama Forsskál)(1775). Aquac Nutr. 2020;26(5):1724–1735. doi: 10.1111/anu.13123.
- Wu L, Lv X, Zhang Y, Xin Q, Zou Y, Li X. Tartrazine exposure results in histological damage, oxidative stress, immune disorders and gut microbiota dysbiosis in juvenile crucian carp (Carassius carassius). Aquat Toxicol. 2021;241:105998. doi: 10.1016/j.aquatox.2021.105998.
- Elekima, Ibioku, et al. Assessment of ovarian integrity, reproductive hormones, and oxidative stress in Albino rats exposed to tartrazine azo dye. Asian J Biochem Genet Mol Biol. 2020;5(4):9–19. doi: 10.9734/ajbgmb/2020/v5i430136

Nano Trends – A Journal of Nano Technology & Its Applications
| Volume | 27 |
| Issue | 01 |
| Received | 05/11/2024 |
| Accepted | 11/11/2024 |
| Published | 02/01/2025 |
Login
PlumX Metrics
