Evaluation and Fabrication of 3D-Printed Bioactive β-TCP/PCL Scaffolds for Bone Tissue Engineering

Year : 2026 | Volume : 14 | Special Issue 04 | Page : 1 6
By

Rahul Sonavale,

Shubhangi A. Patil,

Puja Malhotra,

Prashant G. Tandale,

  1. Assistant Professor, Department of Biotechnology, Krishna Institute of Science and Technology, Krishna Vishwa Vidyapeeth “Deemed to be University”, Karad, Maharashtra, India
  2. Principal, Department of Pharmaceutical Sciences, KCT’s Krishna College of Pharmacy, Karad, Maharashtra, India
  3. Professor, Department of Prosthodontics, Faculty of Dental Sciences, SGT University, Gurugram, Haryana, India
  4. Assistant Professor, Department of Management Studies, Bharati Vidyapeeth (Deemed to be University), Pune, Maharashtra, India

Abstract

Bone is one of the tissue types that is transplanted the most worldwide. Each year, there are over four million procedures that incorporate the use of bone grafts or substitutes to help heal bone deficiencies. These treatments are still limited greatly, and there is always a demand for help because of trauma, cancer, infection, and arthritis. Because of this, researchers are targeting improvement in developing bioactive three-dimensional (3D) scaffolds that favor the process of bone regeneration. Natural bone is a complex and well-designed natural material, and a successful bone substitute material has two challenges to meet, being both biocompatible and bioactive to allow the growth and differentiation of cells and having adequate mechanical stability after implantation. A hybrid PCL/β-TCP scaffold has been developed to meet these demands. The blended PCL enhances mechanical properties and biocompatibility of the scaffold compared to the scaffold made of PCL alone. In addition, the incorporated β-TCP fortifies the scaffold and can boost the osteogenic potential while the polymer elaborates the mechanical stability of the ceramic scaffolds. We investigated Polycaprolactone (PCL)/beta-tricalcium phosphate (β-TCP) composites based on application mechanical stimulus, as a support framework for engineered bone tissue. 3D structures based on PCL by solvent free 3D printing technique.

Keywords: Bioactive scaffolds, composite biomaterials, 3D scaffold, 3D printing, PCL, TCP, bone tissue.

[This article belongs to Special Issue under section in Journal of Polymer & Composites (jopc)]

How to cite this article: Rahul Sonavale, Shubhangi A. Patil, Puja Malhotra, Prashant G. Tandale. Evaluation and Fabrication of 3D-Printed Bioactive β-TCP/PCL Scaffolds for Bone Tissue Engineering. Journal of Polymer & Composites. 2026; 14(04):1-6.
How to cite this URL: Rahul Sonavale, Shubhangi A. Patil, Puja Malhotra, Prashant G. Tandale. Evaluation and Fabrication of 3D-Printed Bioactive β-TCP/PCL Scaffolds for Bone Tissue Engineering. Journal of Polymer & Composites. 2026; 14(04):1-6. Available from: https://journals.stmjournals.com/jopc/article=2026/view=247494

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Special Issue Subscription Original Research
Volume 14
Special Issue 04
Received 01/06/2026
Accepted 19/06/2026
Published 24/06/2026
Publication Time 23 Days

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