Preparation and Characterization of Clay-Based Hybrid Membranes for Antibacterial Biodegradable Polymer Wound Dressings

Year : 2026 | Volume : 14 | Special Issue 04 | Page : 13 20
By

Snehal Masurkar,

S. K. Mohite,

Sheeth Toppo,

  1. Associate Professor, Department of Microbiology, Krishna Institute of Science and Technology, Krishna Vishwa Vidyapeeth (Deemed to be University), Karad, Satara, Maharashtra, India
  2. Principal, Department of Pharmaceutical Chemistry, Rajarambapu College of Pharmacy, Kasegaon, Maharashtra, India
  3. Assistant Professor, Department of Home Science, Kolhan University, Chaibasa, Jharkhand, India

Abstract

Recent developments in the field of polymer chemistry have resulted in many new forms of Hybrid polymer. This has further revolutionized the application of polymer chemistry in numerous fields. In this research, we manufactured clay-based hybrid membrane by adding clay to the biodegradable matrix of chitosan polymer. It is widely known that microbial and pathogenic organisms are responsible for wound hampering infections such as impetigo. They can spread in bodily fluids and skin, enter the blood through wounds and slow down the healing and repair of tissues. Clay has long historical use as a therapeutic agent with potential use in biomedical applications. Its safe composition, along with its large surface area, availability, and ability to exchange cations make it attractive. This design increases structural and biocompatibility and wound-healing efficiency. The hybrid membranes are a combination of clays, hydraulic ionizing agents – called Zwitterions, silver and terbinafine hydrochloride (TBH). This combination yields both antibacterial as well as antifungal action. The biodegradable polymer serves as a supporting framework, and the clay helps to control the releasing of antimicrobial agents to prevent the growth of pathogens. We evaluated the antimicrobial efficacy employing a zone of inhibition assay against prevalent skin wound pathogens; these hybrid clay membranes were strongly antimicrobial against Candida albicans, Escherichia coli, and Staphylococcus aureus. Our output suggests that these hybrid clay membranes are affordable, scalable, and suitable for powerful and useful treatment of microbial infections. In wound healing solution these membranes provide an advance point of care solution.

Keywords: Hybrid polymer, polymer characterization, biodegradable polymer, Chitosan polymer.

[This article belongs to Special Issue under section in Journal of Polymer & Composites (jopc)]

How to cite this article: Snehal Masurkar, S. K. Mohite, Sheeth Toppo. Preparation and Characterization of Clay-Based Hybrid Membranes for Antibacterial Biodegradable Polymer Wound Dressings. Journal of Polymer & Composites. 2026; 14(04):13-20.
How to cite this URL: Snehal Masurkar, S. K. Mohite, Sheeth Toppo. Preparation and Characterization of Clay-Based Hybrid Membranes for Antibacterial Biodegradable Polymer Wound Dressings. Journal of Polymer & Composites. 2026; 14(04):13-20. Available from: https://journals.stmjournals.com/jopc/article=2026/view=246223

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Special Issue Subscription Original Research
Volume 14
Special Issue 04
Received 19/05/2026
Accepted 29/05/2026
Published 06/06/2026
Publication Time 18 Days

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