Characterization and Antimicrobial Investigations of Isomeric Pr(III) Juglonates

Year : 2025 | Volume : 13 | Special Issue 06 | Page : 545 552
    By

    Mrudula P. Wadekar,

  • Abhaysinh Kadam,

  • Vishwambhar Shinde,

  • Shrikant More,

  1. Assistant Professor, Department of Chemistry, Bharati Vidyapeeth (Deemed to be University), Yashwantrao Mohite College of Arts, Science and Commerce, Erandawane, Pune, Maharashtra, India
  2. Assistant Professor, Department of Chemistry, Bharati Vidyapeeth (Deemed to be University), Yashwantrao Mohite College of Arts, Science and Commerce, Erandawane, Pune, Maharashtra, India
  3. Assistant Professor, Department of Chemistry, Bharati Vidyapeeth (Deemed to be University), Yashwantrao Mohite College of Arts, Science and Commerce, Erandawane, Pune, Maharshtra, India
  4. Research Scholar, Department of Chemistry, Bharati Vidyapeeth (Deemed to be University), Yashwantrao Mohite College of Arts, Science and Commerce, Erandawane, Pune, Maharshtra, India

Abstract

Hydroxy napthoquinone derivatives constitute an interesting group of ligands which is recognized as ‘Juglones’. Isomeric Lawsone-Juglone and Phthiocol-Plumbagin are the most important members of the Juglone series and are biologically active, having natural origin. They form isomeric pairs of ligands resulting into isomeric pairs of metal chelates. The isomerism is occurring due to formation of either five or six membered rings in the metal chelates. In the present work Prasodymium chelates of some isomeric Juglones, namely Pr(III)lawsonate and Pr(III)juglonate, Pr(III)phthiocolate and Pr(III)plumbaginate are synthesized and studied using elemental analysis, UV IR spectroscopy, TGA, XRD and SEM. Antimicrobial activity of the Pr(III) chelates are studied against four bacterial strains. The data and results are employed for investigating structural and antimicrobial properties with particular emphasis on the ‘effect of chelation’ and ‘effect of ring size’ on the properties of the chelates. All Pr(III) juglonates are eight coordination chelates. The chelation is through six oxygen from the juglones and through two oxygen from two water molecules. The IR study reveals that, six membered juglone and plumbagin chelates seems to be more stable than five membered lawsone and phthiocol chelates. Effect of ring isomerism is reflected on the antibacterial activity of isomeric chelates showing greater activity in six members juglonate and less activity in plumbaginate for selected bacterial strains. Amoung all chelates Pr(III) plumbaginate exbits highest activity against s.aureius.

Keywords: Hydroxynapthoquinones, Juglones, Pr(III) chelates, IR, Antimicrobial activity.

[This article belongs to Special Issue under section in Journal of Polymer and Composites (jopc)]

How to cite this article:
Mrudula P. Wadekar, Abhaysinh Kadam, Vishwambhar Shinde, Shrikant More. Characterization and Antimicrobial Investigations of Isomeric Pr(III) Juglonates. Journal of Polymer and Composites. 2025; 13(06):545-552.
How to cite this URL:
Mrudula P. Wadekar, Abhaysinh Kadam, Vishwambhar Shinde, Shrikant More. Characterization and Antimicrobial Investigations of Isomeric Pr(III) Juglonates. Journal of Polymer and Composites. 2025; 13(06):545-552. Available from: https://journals.stmjournals.com/jopc/article=2025/view=232516


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Special Issue Subscription Original Research
Volume 13
Special Issue 06
Received 09/06/2025
Accepted 19/07/2025
Published 13/09/2025
Publication Time 96 Days
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