Harish Reddy Gantla,
Vadakattu Prabhakar,
Harish Chandra Mohanta,
A. Anandhan,
Parul Goyal,
Radha Seelaboyina,
- Associate Professor, Department of Computer Science & Engineering, Vignan Institute of Technology and Science, Telangana, India
- Assistant Professor, Department of Computer Science & Engineering, Sreenidhi Institute of Science and Technology, Telangana, India
- Professor, Department of Electronics and Communication Engineering, Centurion University of Technology and Management, Odisha, India
- Associate Professor, Department of Chemistry, Erode Sengunthar Engineering College, Thudupathi, Perundurai, Tamil Nadu, India
- Professor, Department of Computer Science & Engineering, M. M. Engineering College, Maharishi Markandeshwar Deemed to be University, Mullana, Ambala, Haryana, India
- Associate Professor, Department of Computer Science and Engineering, Geethanjali College of Engineering and Technology, Hyderabad, Telangana, India
Abstract
Polymer-based flexible biosensors have emerged as a pivotal technology in continuous health monitoring, yet their deployment in real-world settings is often hindered by undetected micro-defects and signal distortion caused during fabrication or usage. Existing diagnostic frameworks typically rely on post-hoc processing or bulky instrumentation, failing to offer scalable, real-time detection during additive manufacturing workflows. This study introduces an end-to-end, thermographic imaging-integrated framework for in-situ defect identification during the additive manufacturing of polymer composites, guided by a lightweight convolutional neural network (CNN) architecture. The system fuses thermal signatures with structural cues to detect anomalies embedded within multilayer flexible substrates. A streamlined fabrication pipeline—including conductive polymer deposition, thermal data capture, and edge-based CNN classification—enables robust, near-instantaneous feedback during biosensor assembly. Experimental evaluations demonstrate that the proposed system achieves a classification accuracy of 96.4% with a latency reduction of 28.3% compared to traditional offline inspection methods. Signal fidelity under deformation stress conditions remains consistently above 92%, even in high-strain regions. This approach not only enhances the reliability and production yield of wearable biosensors but also sets a precedent for embedding explainable AI-driven quality control directly into smart manufacturing cycles—paving the way for self-validating, adaptive biomedical devices suited for the evolving landscape of personalized, IoT-enabled healthcare.
Keywords: Wearable biosensors, thermographic imaging, flexible polymers, deep learning, in-situ defect detection.
[This article belongs to Special Issue under section in Journal of Polymer and Composites (jopc)]
Harish Reddy Gantla, Vadakattu Prabhakar, Harish Chandra Mohanta, A. Anandhan, Parul Goyal, Radha Seelaboyina. ML-Driven Defect Detection in Additive Manufacturing of Polymer Composites Using Thermal Imaging. Journal of Polymer and Composites. 2025; 13(06):201-215.
Harish Reddy Gantla, Vadakattu Prabhakar, Harish Chandra Mohanta, A. Anandhan, Parul Goyal, Radha Seelaboyina. ML-Driven Defect Detection in Additive Manufacturing of Polymer Composites Using Thermal Imaging. Journal of Polymer and Composites. 2025; 13(06):201-215. Available from: https://journals.stmjournals.com/jopc/article=2025/view=228953
References
- Yoon, J., Kwon, N., Lee, Y., Kim, S., Lee, T., and Choi, J.-W., “Nanotechnology-Based Wearable Electrochemical Biosensor for Disease Diagnosis,” ACS Sensors, vol. 10, no. 3, pp. 1675–1689, Mar. 2025, doi: 10.1021/acssensors.4c03371.
- Murugesan Chandran, M., Veerapandian, M., Dhanasekaran, B., Govindaraju, S., and Yun, K., “Advanced nanomaterials for health monitoring and diagnostics in next-generation wearable sensors,” Mater. Sci. Eng. R Rep., vol. 165, p. 101015, 2025, doi: 10.1016/j.mser.2025.101015.
- Abhinav, V., Basu, P., Verma, S. S., Verma, J., Das, A., Kumari, S., Yadav, P. R., and Kumar, V., “Advancements in Wearable and Implantable BioMEMS Devices: Transforming Healthcare Through Technology,” Micromachines, vol. 16, no. 5, p. 522, 2025, doi: 10.3390/mi16050522.
- Pereira, C. R., Pereira, A. M., Teixeira, J. S., Sousa, A. R., Queirós, G. P., Costa, R. S., and Nunes, M. S., “Advanced energy storage systems as power sources for biosensing technologies,” 2025, doi: 10.1016/bs.pmbts.2025.05.012.
- Cha, S., Choi, M. Y., Kim, M. J., Sim, S. B., Haizan, I., and Choi, J.-H., “Electrochemical Microneedles for Real-Time Monitoring in Interstitial Fluid: Emerging Technologies and Future Directions,” Biosensors, vol. 15, no. 6, p. 380, 2025, doi: 10.3390/bios15060380.
- Mu, G., et al., “Recent advancements in wearable sensors: integration with machine learning for human–machine interaction,” RSC Adv., vol. 15, pp. 7844–7854, Mar. 2025, doi: 10.1039/D5RA00167F.
- Duan, H., Peng, S., He, S., Tang, S.-Y., Wang, C. H., and Li, M., “Wearable Electrochemical Biosensors for Advanced Healthcare Monitoring,” Adv. Sci., vol. 12, no. 2, p. 2411433, Nov. 2024, doi: 10.1002/advs.202411433.
- Jiao, Y., and Yu, X., “Recent advances in wearable electrochemical sensors for in situ detection of biochemical markers,” Sci. China Mater., vol. 68, pp. 755–774, Feb. 2025, doi: 10.1007/s40843-024-2960-1.
- Dervisevic, M., Esser, L., Chen, Y., Alba, M., Prieto-Simon, B., and Voelcker, N. H., “High-density microneedle array-based wearable electrochemical biosensor for detection of insulin in interstitial fluid,” Biosens. Bioelectron., p. 116995, 2024, doi: 10.1016/j.bios.2024.116995.
- Flynn, C. D., Chang, D., Mahmud, A., Yousefi, H., Das, J., Riordan, K. T., Sargent, E. H., and Kelley, S. O., “Nanobiosensors for precision medicine,” Nat. Rev. Bioeng., vol. 1, pp. 560–577, 2023.
- Wu, J., Liu, H., Chen, W., Ma, B., and Ju, H., “Next-generation biosensing technologies,” Nat. Rev. Bioeng., vol. 1, pp. 346–361, 2023.
- Saha, T., Del Caño, R., Mahato, K., De la Paz, E., Chen, C., Ding, S., Yin, L., and Wang, J., “Advances in wearable biosensor interfaces,” Chem. Rev., vol. 123, pp. 7854–7876, 2023.
- Li, S., Zhang, H., Zhu, M., Kuang, Z., Li, X., Miao, S., Zhang, Z., Lou, X., Li, H., and Xia, F., “Functional nanomaterials for wearable biosensors,” Chem. Rev., vol. 123, pp. 7953–7982, 2023.
- Dezhakam, E., Khalilzadeh, B., Mahdipour, M., Isildak, I., Yousefi, H., Ahmadi, M., Naseri, A., and Rahbarghazi, R., “Wearable biosensors for continuous health monitoring,” Biosens. Bioelectron., vol. 222, p. 114980, 2023.
- Ye, C., Lukas, H., Wang, M., Lee, Y., and Gao, W., “Molecularly imprinted polymer-based wearable biosensors,” Chem. Soc. Rev., vol. 53, pp. 7960–7982, 2024.
- Bai, J., Liu, D., Tian, X., Wang, Y., Cui, B., Yang, Y., Dai, S., Lin, W., Zhu, J., Wang, J., Xu, A., Gu, Z., and Zhang, S., “Wearable biosensors based on fiber-integrated electrodes for multiplexed sweat analysis,” Sci. Adv., vol. 10, p. eadl1856, 2024.
- Wang, X., Zhou, J., and Wang, H., “Flexible Electrochemical Biosensors for In Vivo Real-Time Monitoring,” Cell Rep. Phys. Sci., vol. 5, p. 101801, 2024.
- Wang, Y., Duan, H., Yalikun, Y., Cheng, S., and Li, M., “Smart wearable platforms for noninvasive health monitoring,” Talanta, vol. 266, p. 125026, 2024.
- Duan, H., Tang, S.-Y., Goda, K., and Li, M., “Electrochemical sensing technologies for wearable biosensor systems,” Biosens. Bioelectron., vol. 246, p. 115918, 2024.
- A. I. Azizan, S. Taufik, M. N. Norizan, and J. I. A. Rashid, “Flexible and transparent wearable electrochemical sensors,” Biosens. Bioelectron.: X, vol. 13, p. 100291, 2023.
- Liu, Z. Cai, Y. Ye, M. Zhou, H. Liao, and Y. Yi, “An overview of flexible sensors: Development, application, and challenges,” Sensors, vol. 23, p. 817, 2023, doi: 10.3390/s23020817.
- Hu, Z. Ma, F. Zhao, and S. Guo, “Recent advances in self-powered wearable flexible sensors for human gaits analysis,” Nanomaterials, vol. 14, p. 1173, 2024, doi: 10.3390/nano14071173.
- Gao, Z. Yang, J. Choi, C. Wang, G. Dai, and J. Yang, “Triboelectric nanogenerators for preventive health monitoring,” Nanomaterials, vol. 14, p. 336, 2024, doi: 10.3390/nano14020336.
- Chen, K. Lv, R. Zhao, Y. Lu, and P. Chen, “Flexible and stable GaN piezoelectric sensor for motion monitoring and fall warning,” Nanomaterials, vol. 14, p. 2044, 2024, doi: 10.3390/nano14092044.
- Duan, Y. Zhang, Y. Zhang, P. Zhu, and Y. Mao, “Recent advances of stretchable nanomaterial-based hydrogels for wearable sensors and electrophysiological signals monitoring,” Nanomaterials, vol. 14, p. 1398, 2024, doi: 10.3390/nano14071398.
- Qu et al., “Electric resistance of elastic strain sensors—Fundamental mechanisms and experimental validation,” Nanomaterials, vol. 13, p. 1813, 2023, doi: 10.3390/nano13101813.
- Tajitsu et al., “Application of braided piezoelectric poly-L-lactic acid cord sensor to sleep bruxism detection system with less physical or mental stress,” Micromachines, vol. 15, p. 86, 2023, doi: 10.3390/mi15010086.
- Zou et al., “Hybrid pressure sensor based on carbon nano-onions and hierarchical microstructures with synergistic enhancement mechanism for multi-parameter sleep monitoring,” Nanomaterials, vol. 13, p. 2692, 2023, doi: 10.3390/nano13152692.
- Cao et al., “Self-healable PEDOT:PSS-PVA nanocomposite hydrogel strain sensor for human motion monitoring,” Nanomaterials, vol. 13, p. 2465, 2023, doi: 10.3390/nano13132465.
- Z. Cao, X. Xu, C. He, and Z. Peng, “Electrospun nanofibers hybrid wrinkled micropyramidal architectures for elastic self-powered tactile and motion sensors,” Nanomaterials, vol. 13, p. 1181, 2023, doi: 10.3390/nano13071181.

Journal of Polymer & Composites
| Volume | 13 |
| Special Issue | 06 |
| Received | 13/07/2025 |
| Accepted | 01/08/2025 |
| Published | 14/08/2025 |
| Publication Time | 32 Days |
Login
PlumX Metrics