Advancements in Polymeric Capillary Materials for Chromatographic Applications

Year : 2025 | Volume : 13 | Special Issue 04 | Page : 137 144
    By

    Amar Mohite,

  • Jayant Rajaram Pawar,

  • Rohan S. Phatak,

  1. Researcher, Department of Research, Krishna Vishwa Vidyapeeth (Deemed to be University), Karad, Maharshtra, India
  2. Associate Professor, Department of Biotechnology, Krishna Institute of Science and Technology, Krishna Vishwa Vidyapeeth (Deemed to be University), Karad, Maharshtra, India
  3. Assistant Professor, Department of Pharmacognosy, Krishna Institute of Pharmacy, Krishna Vishwa Vidyapeeth (Deemed to be University), Karad, Maharshtra, India

Abstract

Traditionally, glass capillaries have been the material of choice due to their inertness, transparency, and precision in delivering small sample volumes. However, glass capillaries have significant drawbacks, including fragility, limited flexibility, and difficulties in modification for specialized applications. Recent advancements in polymer chemistry have introduced novel polymeric capillary materials that offer several advantages over conventional glass capillaries. Additionally, they exhibit enhanced durability and resistance to a broad range of chemicals, expanding their applicability in complex analytical procedures. These materials can be engineered to possess specific surface properties through polymer modifications and specialized coatings, improving sample adhesion and migration behavior. Such enhancements contribute to more accurate and reproducible chromatographic results, addressing the increasing demand for high-performance analytical tools in modern laboratories. The development of polymeric capillaries also facilitates miniaturization and integration into advanced analytical systems, such as microfluidic devices, where traditional glass materials may be impractical. Moreover, polymeric capillaries can be produced more cost-effectively and in diverse geometries, allowing for tailored solutions to specific analytical challenges. This paper explores the evolution of polymeric capillary materials, their functional advantages over traditional glass capillaries, and their expanding role in analytical chemistry. It also discusses the potential future directions for polymer innovation to meet the growing needs of precise and efficient chromatographic analysis.

Keywords: Polymeric capillaries, chromatography, polydimethylsiloxane, polytetrafluoroethylene, surface modification, analytical chemistry.

[This article belongs to Special Issue under section in Journal of Polymer and Composites (jopc)]

How to cite this article:
Amar Mohite, Jayant Rajaram Pawar, Rohan S. Phatak. Advancements in Polymeric Capillary Materials for Chromatographic Applications. Journal of Polymer and Composites. 2025; 13(04):137-144.
How to cite this URL:
Amar Mohite, Jayant Rajaram Pawar, Rohan S. Phatak. Advancements in Polymeric Capillary Materials for Chromatographic Applications. Journal of Polymer and Composites. 2025; 13(04):137-144. Available from: https://journals.stmjournals.com/jopc/article=2025/view=217913


References

  1. RANJAN S, Chaitali RO, SINHA SK. Gas chromatography–mass spectrometry (GC-MS): a comprehensive review of synergistic combinations and their applications in the past two decades. Journal of Analytical Sciences and Applied Biotechnology. 2023 Dec 30;5(2):5-2.
  2. Li Y, Miao S, Tan J, Zhang Q, Chen DD. Capillary Electrophoresis: A three-year literature review. Analytical Chemistry. 2024 Apr 10;96(20):7799-816.
  3. Svec F, Lv Y. Advances and recent trends in the field of monolithic columns for chromatography. Analytical chemistry. 2015 Jan 6;87(1):250-73.
  4. Vuckovic D. Current trends and challenges in sample preparation for global metabolomics using liquid chromatography–mass spectrometry. Analytical and bioanalytical chemistry. 2012 Jun;403(6):1523-48.
  5. De Vos J, Broeckhoven K, Eeltink S. Advances in ultrahigh-pressure liquid chromatography technology and system design. Analytical chemistry. 2016 Jan 5;88(1):262-78.
  6. Zhang J, Chen J, Peng S, Peng S, Zhang Z, Tong Y, Miller PW, Yan XP. Emerging porous materials in confined spaces: from chromatographic applications to flow chemistry. Chemical Society Reviews. 2019;48(9):2566-95.
  7. Ramos‐Payán M, Ocaña‐Gonzalez JA, Fernández‐Torres RM, Llobera A, Bello‐López MÁ. Recent trends in capillary electrophoresis for complex samples analysis: a review. Electrophoresis. 2018 Jan;39(1):111-25.
  8. Fallahi H, Zhang J, Phan HP, Nguyen NT. Flexible microfluidics: Fundamentals, recent developments, and applications. Micromachines. 2019 Nov 29;10(12):830.
  9. Dong J, Fu Q, Li H, Xiao J, Yang B, Zhang B, Bai Y, Song T, Zhang R, Gao L, Cai J. Reaction-induced strong metal–support interactions between metals and inert boron nitride nanosheets. Journal of the American Chemical Society. 2020 Sep 14;142(40):17167-74.
  10. Siraj N, Hashmi SA, Verma S. State‐of‐the‐art review on the high‐performance poly (ether ether ketone) composites for mechanical, tribological and bioactive characteristics. Polymers for Advanced Technologies. 2022 Oct;33(10):3049-77.
  11. Nemani SK, Annavarapu RK, Mohammadian B, Raiyan A, Heil J, Haque MA, Abdelaal A, Sojoudi H. Surface modification of polymers: methods and applications. Advanced Materials Interfaces. 2018 Dec;5(24):1801247.
  12. Miller JM, Astles R, Baszler T, Chapin K, Carey R, Garcia L, Gray L, Larone D, Pentella M, Pollock A, Shapiro DS. Guidelines for safe work practices in human and animal medical diagnostic laboratories. MMWR Surveill Summ. 2012;6(61):1-02.
  13. Yang DY, Bambach M, Cao J, Duflou JR, Groche P, Kuboki T, Sterzing A, Tekkaya AE, Lee CW. Flexibility in metal forming. Cirp Annals. 2018 Jan 1;67(2):743-65.
  14. Xu X, He L, Zhu B, Li J, Li J. Advances in polymeric materials for dental applications. Polymer Chemistry. 2017;8(5):807-23.
  15. Desmet G, de Beeck JO, Van Raemdonck G, Van Mol K, Claerebout B, Van Landuyt N, Jacobs P. Separation efficiency kinetics of capillary flow micro-pillar array columns for liquid chromatography. Journal of Chromatography A. 2020 Aug 30;1626:461279.
  16. Berlanda SF, Breitfeld M, Dietsche CL, Dittrich PS. Recent advances in microfluidic technology for bioanalysis and diagnostics. Analytical chemistry. 2020 Nov 10;93(1):311-31.
  17. Seeley JV, Seeley SK. Multidimensional gas chromatography: fundamental advances and new applications. Analytical Chemistry. 2013 Jan 15;85(2):557-78.
  18. Gimondi S, Ferreira H, Reis RL, Neves NM. Microfluidic devices: a tool for nanoparticle synthesis and performance evaluation. ACS nano. 2023 Jul 27;17(15):14205-28.
  19. Zhai L, Narkar A, Ahn K. Self-healing polymers with nanomaterials and nanostructures. Nano Today. 2020 Feb 1;30:100826.
  20. Wang M, Gong Q, Liu W, Tan S, Xiao J, Chen C. Applications of capillary electrophoresis in the fields of environmental, pharmaceutical, clinical, and food analysis (2019–2021). Journal of Separation Science. 2022 Jun;45(11):1918-41.
  21. Omkar Sakpal, Shivsagar Tewary, Shubha Joshi, Ajay Gaikwad, Abhijeet Kore. Development of Novel Polymeric Articulating Papers for Enhanced Occlusal Contact Assessment in Dentistry. Journal of Polymer and Composites. 2024; 13(01):1004-1011.
  22. Deirram N, Zhang C, Kermaniyan SS, Johnston AP, Such GK. pH‐responsive polymer nanoparticles for drug delivery. Macromolecular rapid communications. 2019 May;40(10):1800917.
  23. Nasiri R, Shamloo A, Ahadian S, Amirifar L, Akbari J, Goudie MJ, Lee K, Ashammakhi N, Dokmeci MR, Di Carlo D, Khademhosseini A. Microfluidic‐based approaches in targeted cell/particle separation based on physical properties: fundamentals and applications. Small. 2020 Jul;16(29):2000171.
  24. Anagha A. Raut, G.R. Pathade. Development of Polymer-based Mulch Films for Disease Suppression. Journal of Polymer and Composites. 2024; 13(01):856-863.
  25. Khan I, Saeed K, Khan I. Nanoparticles: Properties, applications and toxicities. Arabian journal of chemistry. 2019 Nov 1;12(7):908-31.
Special Issue Subscription Review Article
Volume 13
Special Issue 04
Received 12/03/2025
Accepted 01/04/2025
Published 26/05/2025
Publication Time 75 Days
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