Advancements in Polymer Chemistry for Biomedical Applications: A Focus on Injection Guides

Year : 2025 | Volume : 13 | Special Issue 04 | Page : 129-136
    By

    Rajashri Bhagwat Karale,

  1. Associate Professor, Department of Nursing Sciences, Krishna Vishwa Vidyapeeth (Deemed to be University), Karad, Maharshtra, India

Abstract

document.addEventListener(‘DOMContentLoaded’,function(){frmFrontForm.scrollToID(‘frm_container_abs_197988’);});Edit Abstract & Keyword

Polymers have revolutionized biomedical applications, offering versatility, biocompatibility, and cost-effective manufacturing. This paper explores the role of polymer chemistry in the development of an advanced injection guide for precise drug delivery, aiming to enhance both safety and efficiency in clinical settings. Emphasis is placed on polymer selection, structural design, and functional modifications to improve injection procedures. By leveraging biodegradable and biocompatible polymers, the guide minimizes adverse tissue reactions while ensuring controlled degradation when necessary. By integrating polymer composites, the device optimizes injection angle determination, mechanical stability, and ease of use. Smart polymers with stimuli-responsive properties can further enhance performance by adapting to temperature or pH changes, improving targeted delivery. Furthermore, incorporating nanotechnology and 3D printing techniques allows for customized designs, ensuring precision and adaptability across various medical applications. Injection guides play a crucial role in ensuring accurate and controlled delivery of medications, reducing the risk of complications such as improper dosing, tissue damage, or patient discomfort. This innovative approach to injection guidance has the potential to reduce complications, improve drug bioavailability, and enhance user experience for both healthcare professionals and patients. The continued advancement of polymer science will drive further improvements, paving the way for next-generation biomedical devices with enhanced functionality and patient outcomes.

Keywords: Polymer chemistry, biomedical applications, injection guide, biocompatibility, polymer composites, drug delivery, nanocomposites.

[This article belongs to Special Issue under section in Journal of Polymer and Composites (jopc)]

How to cite this article:
Rajashri Bhagwat Karale. Advancements in Polymer Chemistry for Biomedical Applications: A Focus on Injection Guides. Journal of Polymer and Composites. 2025; 13(04):129-136.
How to cite this URL:
Rajashri Bhagwat Karale. Advancements in Polymer Chemistry for Biomedical Applications: A Focus on Injection Guides. Journal of Polymer and Composites. 2025; 13(04):129-136. Available from: https://journals.stmjournals.com/jopc/article=2025/view=0


document.addEventListener(‘DOMContentLoaded’,function(){frmFrontForm.scrollToID(‘frm_container_ref_197988’);});Edit

References

  1. Frid AH, Kreugel G, Grassi G, Halimi S, Hicks D, Hirsch LJ, Smith MJ, Wellhoener R, Bode BW, Hirsch IB, Kalra S. New insulin delivery recommendations. InMayo Clinic Proceedings 2016 Sep 1 (Vol. 91, No. 9, pp. 1231-1255). Elsevier.
  2. Gaspar R, Duncan R. Polymeric carriers: preclinical safety and the regulatory implications for design and development of polymer therapeutics. Advanced drug delivery reviews. 2009 Nov 12;61(13):1220-31.
  3. Kyriakides TR, Raj A, Tseng TH, Xiao H, Nguyen R, Mohammed FS, Halder S, Xu M, Wu MJ, Bao S, Sheu WC. Biocompatibility of nanomaterials and their immunological properties. Biomedical Materials. 2021 Mar 11;16(4):042005.
  4. Graziano A, Jaffer S, Sain M. Review on modification strategies of polyethylene/polypropylene immiscible thermoplastic polymer blends for enhancing their mechanical behavior. Journal of elastomers & plastics. 2019 Jun;51(4):291-336.
  5. Javaid M, Haleem A, Singh RP, Suman R. 3D printing applications for healthcare research and development. Global Health Journal. 2022 Dec 1;6(4):217-26.
  6. Yang S, Song Z, He Z, Ye X, Li J, Wang W, Zhang D, Li Y. A review of chitosan-based shape memory materials: Stimuli-responsiveness, multifunctionalities and applications. Carbohydrate Polymers. 2024 Jan 1;323:121411.
  7. Kempe S, Mäder K. In situ forming implants—an attractive formulation principle for parenteral depot formulations. Journal of controlled release. 2012 Jul 20;161(2):668-79.
  8. Darie-Niță RN, Râpă M, Frąckowiak S. Special features of polyester-based materials for medical applications. Polymers. 2022 Feb 27;14(5):951.
  9. Amran M, Lee YH, Fediuk R, Murali G, Mosaberpanah MA, Ozbakkaloglu T, Yong Lee Y, Vatin N, Klyuev S, Karelia M. Palm oil fuel ash-based eco-friendly concrete composite: A critical review of the long-term properties. Materials. 2021 Nov 22;14(22):7074.
  10. Mallineni SK, Nuvvula S, Matinlinna JP, Yiu CK, King NM. Biocompatibility of various dental materials in contemporary dentistry: a narrative insight. Journal of investigative and clinical dentistry. 2013 Feb;4(1):9-19.
  11. Saini RS, Mosaddad SA, Heboyan A. Application of density functional theory for evaluating the mechanical properties and structural stability of dental implant materials. BMC Oral Health. 2023 Dec 1;23(1):958.
  12. Singh AB, Khandelwal C, Dangayach GS. Advancements in healthcare materials: unraveling the impact of processing techniques on biocompatibility and performance. Polymer-Plastics Technology and Materials. 2024 May 13:1-37.
  13. Sampath V, Rabinowitz G, Shah M, Jain S, Diamant Z, Jesenak M, Rabin R, Vieths S, Agache I, Akdis M, Barber D. Vaccines and allergic reactions: The past, the current COVID‐19 pandemic, and future perspectives. Allergy. 2021 Jun;76(6):1640-60.
  14. Ali R. Advanced Electrohydrodynamic Atomisation Engineered Microneedle Coatings (Doctoral dissertation, De Montfort University).
  15. Zhai W, Bai L, Zhou R, Fan X, Kang G, Liu Y, Zhou K. Recent progress on wear‐resistant materials: designs, properties, and applications. Advanced Science. 2021 Jun;8(11):2003739.
  16. Kohn WG, Collins AS, Cleveland JL, Harte JA, Eklund KJ, Malvitz DM. Guidelines for infection control in dental health-care settings-2003. MMWR Recomm Rep. 2003 Dec 19;52(17):1-61.
  17. Zarrintaj P, Saeb MR, Jafari SH, Mozafari M. Application of compatibilized polymer blends in biomedical fields. InCompatibilization of polymer blends 2020 Jan 1 (pp. 511-537). Elsevier.
  18. Sola A, Bellucci D, Cannillo V. Functionally graded materials for orthopedic applications–an update on design and manufacturing. Biotechnology advances. 2016 Sep 1;34(5):504-31.
  19. Melo GB, da Cruz NF, Emerson GG, Rezende FA, Meyer CH, Uchiyama S, Carpenter J, Shiroma HF, Farah ME, Maia M, Rodrigues EB. Critical analysis of techniques and materials used in devices, syringes, and needles used for intravitreal injections. Progress in Retinal and Eye Research. 2021 Jan 1;80:100862.
  20. Bharadwaaj SK, Jaudan M, Kushwaha P, Saxena A, Saha B. Exploring cutting-edge approaches in plastic recycling for a greener future. Results in Engineering. 2024 Aug 13:102704.
  21. Harun-Ur-Rashid M, Imran AB. Emerging Trends in Engineering Polymers: A Paradigm Shift in Material Engineering. Recent Progress in Materials. 2024 Sep;6(3):1-37.
  22. Fischer D, Li Y, Ahlemeyer B, Krieglstein J, Kissel T. In vitro cytotoxicity testing of polycations: influence of polymer structure on cell viability and hemolysis. Biomaterials. 2003 Mar 1;24(7):1121-31.
  23. Xin Y, Hu T, Chu PK. In vitro studies of biomedical magnesium alloys in a simulated physiological environment: a review. Acta biomaterialia. 2011 Apr 1;7(4):1452-9.
  24. Wu SJ, Zhao X. Bioadhesive technology platforms. Chemical Reviews. 2023 Nov 16;123(24):14084-118.
  25. Masato D, Piccolo L, Lucchetta G, Sorgato M. Texturing Technologies for Plastics Injection Molding: A Review. Micromachines. 2022 Jul 29;13(8):1211.
  26. Schmalz G, Galler KM. Biocompatibility of biomaterials–Lessons learned and considerations for the design of novel materials. Dental Materials. 2017 Apr 1;33(4):382-93.
  27. Shivani S. kadam, Randhir B. Lad, Shilpa S. Ruikar, Girish R. Pathade. Evaluation of Bio-Based Polymer Composites Containing Guava Leaf Extract for Antimicrobial Functionality. Journal of Polymer and Composites. 2024; 13(01):875-880.
  28. Pradnya Chaudhari, Dr. Shashikiran N.D, Dr. Sachin gugawad, Dr. Namrata Gaonkar, Dr. Swapnil Taur, Dr. Savita Hadakar. Comparative Assessment of Antibacterial Effectiveness, Bioactivity, Fluoride Release, and Microleakage of Various Bioactive Smart Composites: An In Vitro Investigation.. Journal of Polymer and Composites. 2024; 12(03):76-86.
  29. Santulli C, Palanisamy S, Kalimuthu M. Pineapple fibers, their composites and applications. Plant Fibers, their Composites, and Applications. 2022;323–46.
  30. Palanisamy S, Kalimuthu M, Santulli C, Palaniappan M, Nagarajan R, Fragassa C. Tailoring Epoxy Composites with Acacia caesia Bark Fibers: Evaluating the Effects of Fiber Amount and Length on Material Characteristics. Fibers. 2023 Jul 17;11(7):63.
  31. Karthik A, Bhuvaneshwaran M, Senthil Kumar MS, Palanisamy S, Palaniappan M, Ayrilmis N. A Review on Surface Modification of Plant Fibers for Enhancing Properties of Biocomposites. Chemistry Select. 2024 Jun 3;9(21).
  32. Palaniappan M, Palanisamy S, Khan R, H.Alrasheedi N, Tadepalli S, Murugesan T mani, et al. Synthesis and suitability characterization of microcrystalline cellulose from Citrus x sinensis sweet orange peel fruit waste-based biomass for polymer composite applications. Journal of Polymer Research. 2024 Mar 19;31(4). Available from: http://dx.doi.org/10.1007/s10965-024-03946-0
  33. Palanisamy S, Kalimuthu M, Palaniappan M, Alavudeen A, Rajini N, Santulli C, et al. Characterization of Acacia caesia Bark Fibers (ACBFs). Journal of Natural Fibers. 2021 Nov 1;19(15):10241–52.
Special Issue Subscription Review Article
Volume 13
Special Issue 04
Received 28/02/2025
Accepted 08/04/2025
Published 24/05/2025
Publication Time 85 Days
109

[first_name] [last_name]

My IP

PlumX Metrics