Advances in Biodegradable Polymer-based Drug Delivery Systems

Year : 2025 | Volume : 13 | Special Issue 04 | Page : 326 338
    By

    Jadhav N. R.,

  • Atul Patil,

  • H. U. Karne,

  • Shankar Lal Soni,

  1. Professor and Dean, Department of Pharmaceutics, Krishna Vishwa Vidyapeeth (Deemed to be University), Krishna Institute of Pharmacy, Karad, Maharashtra, India
  2. Professor, Department of Mechanical Engineering, Dr. D.Y. Patil Institute of Technology, Pimpri, Pune, Maharashtra, India
  3. Assistant Professor, Department of Chemical Engineering, Vishwakarma Institute of Technology, Pune, Maharashtra, India
  4. Associate Professor, Department of Pharmacy, Arya College of Pharmacy, Jaipur, Rajasthan, India

Abstract

An intriguing new approach to manage medication release that may assist with issues like making the therapeutic impact last longer, reducing the danger of side effects, and persuading patients to follow through with their treatment programs is biodegradable polymer-based drug delivery systems (DDS). By developing systems that can break down within the body, biodegradable polymers have revolutionised the way medications are administered. They so have less negative effects and do not need to be physically removed. Usually composed of either natural or synthetic ingredients, these polymers may be modified to provide regulated release patterns for a wide range of therapeutic applications including cancer treatment, wound healing, and long-term illness management. The fact that biodegradable polymers in DDS may disintegrate into benign by-products the body can eliminate on its own is their strongest feature. This qualifies them for medicinal usage perfectly. Because they are so flexible, biodegradable polymers provide a great variety of shapes for mixing diverse therapeutic agents including proteins, peptides, small molecules, and nucleic acids hydrogels, implants, nanoparticles, and microparticles. These systems may also be designed to respond to certain body states such pH, temperature, or enzymes. This reduces the adverse effect risk and makes them even more beneficial as medications. Recent advancements in biodegradable polymer-based DDS have concentrated on improving the physical properties of the polymers such that they may be used in certain medical applications.

Keywords: Biodegradable polymers, Drug delivery systems, Controlled release, Nanotechnology, Therapeutic efficacy.

[This article belongs to Special Issue under section in Journal of Polymer and Composites (jopc)]

How to cite this article:
Jadhav N. R., Atul Patil, H. U. Karne, Shankar Lal Soni. Advances in Biodegradable Polymer-based Drug Delivery Systems. Journal of Polymer and Composites. 2025; 13(04):326-338.
How to cite this URL:
Jadhav N. R., Atul Patil, H. U. Karne, Shankar Lal Soni. Advances in Biodegradable Polymer-based Drug Delivery Systems. Journal of Polymer and Composites. 2025; 13(04):326-338. Available from: https://journals.stmjournals.com/jopc/article=2025/view=211743


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Special Issue Subscription Review Article
Volume 13
Special Issue 04
Received 20/03/2025
Accepted 06/05/2025
Published 01/06/2025
Publication Time 73 Days
325


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