Synthetic and Natural Polymer Composites in Wound Healing and Drug Delivery

Year : 2025 | Volume : 13 | Special Issue 04 | Page : 466 478
    By

    Dol H. S.,

  • Vaishali Patil,

  • Prasanna Kattimani,

  • Mahesh Sharma,

  1. Assistant Professor, Department of Pharmaceutics, Krishna Vishwa Vidyapeeth (Deemed to be University), Krishna Institute of Pharmacy, Karad, Maharashtra, India
  2. Professor, Department of Engineering Science and Humanities, Vishwakarma Institute of Technology, Pune, Maharashtra, India
  3. Assistant Professor, Department of Mechanical Engineering, Dr. D.Y. Patil Institute of Technology, Pimpri, Pune, Maharashtra, India
  4. Professor, Department of Pharmacy, Arya College of Pharmacy, Jaipur, Rajasthan, India

Abstract

Both man-made and natural polymer mixtures have become important materials in wound repair and medicine delivery because they can be used in many ways and work well with living things. The benefits of both man-made and natural polymers are combined in these composites. They have a wide range of mechanical, chemical, and biological qualities that make them useful for many medical uses. In wound healing, polymer mixtures help tissues grow back faster and lower the risk of infection by creating a shield that protects the area and encourages cell growth. Natural polymers like collagen, chitosan, and hyaluronic acid are very bioactive and help wounds heal by acting like the extracellular matrix. However, man-made polymers such as poly(lactic acid) (PLA) and polycaprolactone (PCL) can be easily changed in terms of how quickly they break down and how strong they are, both of which are important for managing the mending process. Polymer mixtures help with controlled, long-lasting, and localised drug release, which lowers the risk of systemic side effects and raises the effectiveness of therapy. You can make these combinations react to certain things, like pH, temperature, or enzyme activity. This makes sure that healing drugs get to the right place to work. Adding nanoparticles or bioactive agents to polymer frameworks also improves the drugs’ absorption and release profile, which opens up new ways to make medicine more personalised. When manufactured and natural polymers are mixed, they help make wound bandages, drug carriers, and tissue scaffolding that work better in special ways.

Keywords: Polymer composites, wound healing, drug delivery, biocompatibility, controlled release.

[This article belongs to Special Issue under section in Journal of Polymer and Composites (jopc)]

How to cite this article:
Dol H. S., Vaishali Patil, Prasanna Kattimani, Mahesh Sharma. Synthetic and Natural Polymer Composites in Wound Healing and Drug Delivery. Journal of Polymer and Composites. 2025; 13(04):466-478.
How to cite this URL:
Dol H. S., Vaishali Patil, Prasanna Kattimani, Mahesh Sharma. Synthetic and Natural Polymer Composites in Wound Healing and Drug Delivery. Journal of Polymer and Composites. 2025; 13(04):466-478. Available from: https://journals.stmjournals.com/jopc/article=2025/view=211732


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Special Issue Subscription Review Article
Volume 13
Special Issue 04
Received 20/03/2025
Accepted 06/05/2025
Published 01/06/2025
Publication Time 73 Days
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