Role of Nasya in Pakshaghata: An Evidence-Based Review Study on Its Anatomical Pathway and Therapeutic Action

Year : 2025 | Volume : 14 | Issue : 02 | Page : 1 8
    By

    Anmol Mahajan,

  • Kalpana Raje,

  • Syamlal S.,

  • Dharmendra Mishra,

  • Nikita Bankoti,

  1. Scholar, Department of Rachana Sharir, Institute of Teaching and Research in Ayurveda (INI), Jamnagar, Gujarat, India
  2. Professor & HOD, Department of Rachana Sharir, Institute of Teaching and Research in Ayurveda (INI), Jamnagar, Gujarat, India
  3. Lecturer, Department of Rachana Sharir, Institute of Teaching and Research in Ayurveda (INI), Jamnagar, Gujarat, India
  4. Assistant Professor, Institute of Teaching and Research in Ayurveda (INI), Jamnagar, Gujarat, India
  5. Assistant Professor, Department of Rachana Sharir, Gangasheel Ayurvedic Medical College and Hospital, Bareilly, Uttar Pradesh, India

Abstract

Introduction: Intranasal administration (Nasya), a time-honoured Ayurvedic procedure, offers a unique advantage in treating pathology of neurological and systemic diseases due to its targeted and non-invasive nature. Pakshaghata, a neurological disorder characterized by hemiplegia in ancient Ayurvedic literature, where it is classified as a Vatavyadhi. Methods: By going through all the available literatures and information, this review study explores the concept of Nasya in the context of Pakshaghata management, investigating the macro and micro channels involved in its potential mechanism of action and the interfacial linkage between the nasal cavity and the brain is elucidated. Results: The intranasal administration of indicated medicine ingredients permeate the channels up to the cavernous sinus, disseminating throughout the cranial cavity and brain. This targeted approach allows for the exertion of systemic effects, acting upon key centres governing neurological, endocrine, and circulatory functions. Discussion: Nasya therapy offers a potential adjuvant and main therapeutic modality for Pakshaghata. The avoidance of first-pass metabolism and the blood-brain barrier enables higher bioavailability of drugs administered through Nasya. Conclusion: The medicine used in Nasya reaches to the targeted structure through two ways, one is the nasal mucosa containing enormous blood vessels and the other is through fine pores in cribriform plate, the absorbed medication can rapidly reach the brain, influencing various neurological, endocrine, and circulatory functions. The brain’s intricate network of neurons and blood vessels allows the absorbed Nasya dravya to act on specific centres and highlight its mechanism and advantages.

Keywords: Anatomical pathway, Hemiplegia, Intranasal administration, Nasya, Pakshaghata

[This article belongs to Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy ]

How to cite this article:
Anmol Mahajan, Kalpana Raje, Syamlal S., Dharmendra Mishra, Nikita Bankoti. Role of Nasya in Pakshaghata: An Evidence-Based Review Study on Its Anatomical Pathway and Therapeutic Action. Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy. 2025; 14(02):1-8.
How to cite this URL:
Anmol Mahajan, Kalpana Raje, Syamlal S., Dharmendra Mishra, Nikita Bankoti. Role of Nasya in Pakshaghata: An Evidence-Based Review Study on Its Anatomical Pathway and Therapeutic Action. Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy. 2025; 14(02):1-8. Available from: https://journals.stmjournals.com/joayush/article=2025/view=217168


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Regular Issue Subscription Review Article
Volume 14
Issue 02
Received 24/04/2025
Accepted 09/05/2025
Published 15/05/2025
Publication Time 21 Days
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